Zobrazeno 1 - 10
of 616
pro vyhledávání: '"Ian Judson"'
Autor:
Jessica Burns, Christopher P. Wilding, Lukas Krasny, Xixuan Zhu, Madhumeeta Chadha, Yuen Bun Tam, Hari PS, Aswanth H. Mahalingam, Alexander T. J. Lee, Amani Arthur, Nafia Guljar, Emma Perkins, Valeriya Pankova, Andrew Jenks, Vanessa Djabatey, Cornelia Szecsei, Frank McCarthy, Chanthirika Ragulan, Martina Milighetti, Theodoros I. Roumeliotis, Stephen Crosier, Martina Finetti, Jyoti S. Choudhary, Ian Judson, Cyril Fisher, Eugene F. Schuster, Anguraj Sadanandam, Tom W. Chen, Daniel Williamson, Khin Thway, Robin L. Jones, Maggie C. U. Cheang, Paul H. Huang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Soft tissue sarcomas (STS) are rare and diverse mesenchymal cancers with limited treatment options. Here we undertake comprehensive proteomic profiling of tumour specimens from 321 STS patients representing 11 histological subtypes. Within l
Externí odkaz:
https://doaj.org/article/9d213184d1a64b60a226a35cf5a6990a
Autor:
Georgios Kantidakis, Saskia Litière, Hans Gelderblom, Marta Fiocco, Ian Judson, Winette T.A. van der Graaf, Antoine Italiano, Sandrine Marréaud, Stefan Sleijfer, Gunhild Mechtersheimer, Christina Messiou, Bernd Kasper
Publikováno v:
Sarcoma, Vol 2022 (2022)
Background. Soft-tissue sarcomas (STS) constitute a rare group of heterogeneous mesenchymal tumours containing more than 100 histologic subtypes. Here, we investigate whether, and if so, to what extent, skeletal metastases affect the outcome of patie
Externí odkaz:
https://doaj.org/article/25ec7fab08104814b3d6fdf06f2f5c0a
Autor:
Axel Le Cesne, Sebastian Bauer, George D. Demetri, Guangyang Han, Luca Dezzani, Qasim Ahmad, Jean-Yves Blay, Ian Judson, Patrick Schöffski, Massimo Aglietta, Peter Hohenberger, Hans Gelderblom
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background PALETTE is a phase 3 trial that demonstrated single-agent activity of pazopanib in advanced soft tissue sarcomas (aSTS). We performed retrospective subgroup analyses to explore potential relationships between patient characteristi
Externí odkaz:
https://doaj.org/article/e7be3d15549546a4b191211c85af8d93
Autor:
Ian Judson, Christina Messiou
Publikováno v:
Gynecologic Oncology Reports, Vol 35, Iss , Pp 100681- (2021)
This is a case of recurrent intravascular leiomyomatosis in a pre-menopausal woman of African-Caribbean heritage. She presented in 2006 with multiple uterine leiomyomata, tumour invading the inferior vena cava (IVC) extending into the right atrium, a
Externí odkaz:
https://doaj.org/article/fc063ba1d3c041b7a04c21e5dc5bfac1
Autor:
Christian Rothermundt, Dimosthenis Andreou, Jean-Yves Blay, Thomas Brodowicz, Ingrid M.E. Desar, Palma Dileo, Hans Gelderblom, Rick Haas, Jens Jakob, Robin L. Jones, Ian Judson, Wolfgang G. Kunz, Berndadette Liegl-Atzwanger, Lars H. Lindner, Christina Messiou, Aisha B. Miah, Peter Reichardt, Joanna Szkandera, Winette T.A. van der Graaf, Winan J. van Houdt, Eva Wardelmann, Silvia Hofer, Thomas Barth, Sebastian Bauer, Veronika Blum, Beata Bode, Sylvie Bonvalot, Judith Bovee, Petra Braam, Jean Martin Broto, Angelo Dei Tos, Dominik Denschlag, Ingrid Desar, Antonia Digklia, Uta Dirksen, Thomas Douchy, Florence Duffaud, Mikael Eriksson, Stefan Fröhling, Alessandro Gronchi, Jenrik Hardes, Wolfgang Hartmann, Peter Hohenberger, Daphne Hompes, Paul Huang, Antoine Italiano, Robin Jones, Günter Köhler, Attila Kollàr, Fatime Krasniqi, Stijn Krol, Wolfgang Kunz, Franel Le Grange, Cécile Le Pechoux, Alexandre LeCesne, Andreas Leithner, Bernadette Liegl-Atzwanger, Lars Lindner, Gunhild Mechtersheimer, Aisha Miah, Daniel Pink, Cleo Romagosa, Piotr Rutkowski, Akmel Safwat, Claudia Sangalli, Khin Thway, Per-Ulf Tunn, Winette Van der Graaf, Winan Van Houdt, Ralph Zachariah, Sander Botter, Thomas Cerny
Publikováno v:
European Journal of Cancer, 180, pp. 158-179
European Journal of Cancer, 180, 158-179
European Journal of Cancer, 180, 158-179
Owing to the rarity and heterogeneity in biology and presentation, there are multiple areas in the diagnosis, treatment and follow-up of soft tissue sarcoma (STS), with no, low-level or conflicting evidence.During the first Consensus Conference on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d0b8b1904e1ba3e1ddb27cdb7906ae
https://hdl.handle.net/2066/290083
https://hdl.handle.net/2066/290083
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0210731 (2019)
OBJECTIVE:Soft tissue sarcoma (STS) is a rare cancer type that when locally advanced or metastatic, is predominantly treated with palliative chemotherapy with the aim of improving both quantity and quality of life. Given modest survival data after co
Externí odkaz:
https://doaj.org/article/fd69f48122db49bda2e580da1d53a3b7
Akademický článek
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Autor:
Paul Workman, Ian Judson, Melani Valenti, Lloyd Kelland, Rachel Grimshaw, Florence Raynaud, Michael Walton, Udai Banerji
Purpose: To establish the pharmacokinetic and pharmacodynamic profile of the heat shock protein 90 (HSP90) inhibitor 17-allylamino, 17-demethoxygeldanamycin (17-AAG) in ovarian cancer xenograft models.Experimental Design: The effects of 17-AAG on gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3335e1dc199534b941bc901ecc76da05
https://doi.org/10.1158/1078-0432.c.6518076
https://doi.org/10.1158/1078-0432.c.6518076
Autor:
Ian Judson, Paul Workman, Florence Raynaud, Johan S. de Bono, Wynne Aherne, Heidi Peachey, Belle Roels, Udai Banerji, Javier Moreno-Farre, Hendrik-Tobias Arkenau, Anna Zetterlund, Anthea Hardcastle, Martin M. Eatock, Mike Walton, Richard H. Wilson, Simon Pacey
Purpose: A phase I study to define toxicity and recommend a phase II dose of the HSP90 inhibitor alvespimycin (17-DMAG; 17-dimethylaminoethylamino-17-demethoxygeldanamycin). Secondary endpoints included evaluation of pharmacokinetic profile, tumor re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::065bf75e34bed031da5b5cfa70f7d2ce
https://doi.org/10.1158/1078-0432.c.6519198
https://doi.org/10.1158/1078-0432.c.6519198
Autor:
Michael Leahy, Juliane M. Jürgensmeier, Helen Young, Barbara Collins, Marcelo Marotti, Elizabeth Barquin, Kate Gardner, Michelle Scurr, Ian Judson
PDF file - 63KB, This figure describes the relationship between time and circulating biomarkers of VEGFR and KIT inhibition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe4a8a7926ade19c45e49d5cc136949
https://doi.org/10.1158/1078-0432.22450013.v1
https://doi.org/10.1158/1078-0432.22450013.v1