Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ian J. Roney"'
Publikováno v:
Engineering Biology (2019)
Drug resistance complicates the treatment of cancer and infectious diseases, and often arises from the elevated expression of a gene that neutralises or reduces drug activity. To investigate this and other expression-based mechanisms of drug resistan
Externí odkaz:
https://doaj.org/article/fed4bb08befb47b78cd2cede2470ea17
Autor:
Ian J Roney, David Z Rudner
Publikováno v:
PLoS Biology, Vol 22, Iss 4, p e3002589 (2024)
Peptidoglycan (PG) and most surface glycopolymers and their modifications are built in the cytoplasm on the lipid carrier undecaprenyl phosphate (UndP). These lipid-linked precursors are then flipped across the membrane and polymerized or directly tr
Externí odkaz:
https://doaj.org/article/5d6e48dc71df4a37923859008ea470c3
Publikováno v:
J Bacteriol
The WalR-WalK two component signaling system in Bacillus subtilis functions in the homeostatic control of the peptidoglycan (PG) hydrolases LytE and CwlO that are required for cell growth. When the activities of these enzymes are low, WalR activates
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
An imaging-integrated microfluidic cell volume sensor was used to evaluate the volumetric growth rate of single cells from a Saccharomyces cerevisiae population exhibiting two phenotypic expression states of the PDR5 gene. This gene grants multidrug
Publikováno v:
Scientific Reports
Conditional gene expression systems that enable inducible and reversible transcriptional control are essential research tools and have broad applications in biomedicine and biotechnology. The reverse tetracycline transcriptional activator is a canoni
Autor:
Afnan Azizi, Wilson Lam, Hilary Phenix, Lioudmila Tepliakova, Ian J. Roney, Daniel Jedrysiak, Alex Power, Vaibhav Gupta, Nada Elnour, Martin Hanzel, Alexandra C. Tzahristos, Shihab Sarwar, Mads Kærn
Publikováno v:
Journal of Biological Engineering
The Registry of Standard Biological Parts imposes sequence constraints to enable DNA assembly using restriction enzymes. Alnahhas et al. (Journal of Biological Engineering 2014, 8:28) recently argued that these constraints should be revised because t
Autor:
Mads Kærn, Afnan Azizi, Vaibhav Gupta, Alexandra C Tzahristos, Ian J. Roney, Lioudmila Tepliakova, Shihab Sarwar, Martin Hanzel, Wilson Lam, Hilary Phenix, Nada Elnour, Daniel Jedrysiak, Alex Power
Publikováno v:
Journal of Biological Engineering
The Registry of Standard Biological Parts imposes sequence constraints to enable DNA assembly using restriction enzymes. Alnahhas et al. (Journal of Biological Engineering 2014, 8:28) recently argued that these constraints should be revised because t