Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Ian J. Miller"'
Autor:
Mike Climstein, Jeremy Hudson, Michael Stapelberg, Ian J. Miller, Nedeljka Rosic, Paul Coxon, James Furness, Joe Walsh
Publikováno v:
PeerJ, Vol 12, p e17674 (2024)
Background Australia is known for its outdoor culture, with a large percentage of its population engaging in outdoor recreational activities, aquatic, non-aquatic and outdoor occupational activities. However, these outdoor enthusiasts face increased
Externí odkaz:
https://doaj.org/article/9ddd1350ab7440ed94c62f9ecb850784
Autor:
Ian J. Miller, Michael Stapelberg, Nedeljka Rosic, Jeremy Hudson, Paul Coxon, James Furness, Joe Walsh, Mike Climstein
Publikováno v:
PeerJ, Vol 11, p e15737 (2023)
Background There is enthusiasm for implementing artificial intelligence (AI) to assist clinicians detect skin cancer. Performance metrics of AI from dermoscopic images have been promising, with studies documenting sensitivity and specificity values e
Externí odkaz:
https://doaj.org/article/cce946eff5984e6391a90e5074a2221c
Autor:
Dain R. Brademan, Ian J. Miller, Nicholas W. Kwiecien, David J. Pagliarini, Michael S. Westphall, Joshua J. Coon, Evgenia Shishkova
Publikováno v:
Patterns, Vol 1, Iss 7, Pp 100122- (2020)
Summary: Researchers now generate large multi-omic datasets using increasingly mature mass spectrometry techniques at an astounding pace, facing new challenges of “Big Data” dissemination, visualization, and exploration. Conveniently, web-based d
Externí odkaz:
https://doaj.org/article/cca67b4f95a24e44a73d4f6683883400
Autor:
Laura V. Flórez, Kirstin Scherlach, Ian J. Miller, Andre Rodrigues, Jason C. Kwan, Christian Hertweck, Martin Kaltenpoth
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Burkholderia bacteria protect the offspring of Lagria beetles against pathogens. Here, Flórez et al. identify an antifungal polyketide that is likely encoded by a horizontally acquired gene cluster on the genome of a dominant, uncultured Burkholderi
Externí odkaz:
https://doaj.org/article/a234ab7eb1c8441fa4cd1a74031757ee
Publikováno v:
mSystems, Vol 2, Iss 6 (2017)
ABSTRACT A symbiotic lifestyle frequently results in genome reduction in bacteria; the isolation of small populations promotes genetic drift and the fixation of deletions and deleterious mutations over time. Transitions in lifestyle, including host r
Externí odkaz:
https://doaj.org/article/b8bdc1a37ac147d98d7f6d3a094cbb02
Publikováno v:
Marine Drugs, Vol 15, Iss 6, p 165 (2017)
Genome mining has become an increasingly powerful, scalable, and economically accessible tool for the study of natural product biosynthesis and drug discovery. However, there remain important biological and practical problems that can complicate or o
Externí odkaz:
https://doaj.org/article/5c97728b0be2436eb82a420ed7d84ed9
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 3, Iss 1, p 21 (2007)
A range of silicon-based tethers and promoters have been investigated for use in the development of a silyl-tethered Pauson-Khand reaction.
Externí odkaz:
https://doaj.org/article/745b744c50594475965b781e4af8e80a
Autor:
Jarred W. Rensvold, Evgenia Shishkova, Yuriy Sverchkov, Ian J. Miller, Arda Cetinkaya, Angela Pyle, Mateusz Manicki, Dain R. Brademan, Yasemin Alanay, Julian Raiman, Adam Jochem, Paul D. Hutchins, Sean R. Peters, Vanessa Linke, Katherine A. Overmyer, Austin Z. Salome, Alexander S. Hebert, Catherine E. Vincent, Nicholas W. Kwiecien, Matthew J. P. Rush, Michael S. Westphall, Mark Craven, Nurten A. Akarsu, Robert W. Taylor, Joshua J. Coon, David J. Pagliarini
Publikováno v:
Nature
Mitochondria are epicentres of eukaryotic metabolism and bioenergetics. Pioneering efforts in recent decades have established the core protein componentry of these organelles(1) and have linked their dysfunction to more than 150 distinct disorders(2,
Autor:
Max Totrov, Denis N. Kazyulkin, Lioubov G. Korotchkina, Sergey Korolev, Andrei V. Gudkov, Ian J. Miller
Publikováno v:
Nucleic Acids Research
Long interspersed nuclear element-1 (L1) is an autonomous non-LTR retrotransposon comprising ∼20% of the human genome. L1 self-propagation causes genomic instability and is strongly associated with aging, cancer and other diseases. The endonuclease
Autor:
Raymond Powell, Phuong-My Do, Mark A. Jensen, Tanja Davidsen, Michael S. Fitzsimons, Karl Rademacher, Daniel P. Miller, Ariz Zubair, Christina K. Yung, Francisco M. Ortuño, Stuti Agrawal, Allison Heath, James C. Angelakos, Kim Cullion, Shenglai Li, Yajing Tang, Janice Lodato, Martin L. Ferguson, Gajanan Ganji, Liming Yang, Kang Han, Sid Joshi, Jesús Pedrosa, Lincoln Stein, Zhining Wang, Jeffrey A. Mazzone, Plamen Martinov, Bessie Rogel, Alex Wilmer, Yuanheng Zhao, Vincent Ferretti, Mathangi Thiagarajan, Zhenyu Zhang, Francois Gerthoffert, Koji Miyauchi, Christian Dompierre, Jonathan Spring, Kaman Wu, Laxmi Lolla, Kyle M. Hernandez, Heather D. Troyer, Ian J. Miller, William P. Wysocki, Joseph Sislow, Linda Xiang, Mark W. Murphy, Joshua S. Miller, Jeffrey Burt, James J. Porter, Shane Wilson, Maksim An, Robert L. Grossman, Sean Sullivan, Bilal Baqar, Renuka Arya, Joseph Tadashi Yamada, Daniela S. Gerhard, Miyuki Fukuma, Maxim Y. Popov, Rosita Bajari, Thomas Nullet, Tara M. Lichtenberg, Jeremiah Savage, Tzintzuni Garcia, Fauzi Gomez, Samantha Rich, Louis M. Staudt, Bedford L. West, Ajinkya Kadam, Kyle A. Schmitt, Phuong L. Pham, Richard Jackson, Michael Ford, Sharon Gaheen, Himanso Sahni, Rowland O. Ogwara, Chang Wang, Victoria E. Kraft, Aishmit Khurana, Sameera S. George, Fay Chu, Colin P. Reid, Christine Yu, Jean C. Zenklusen, Ann Catton, Biju Issac, Justin H. B. Barnowski, Kyle M. J. Kim, Brandon F. Chan, Trevar J. Simmons, Junjun Zhang
Publikováno v:
Nature Genetics. 53:257-262
The National Cancer Institute (NCI) Genomic Data Commons (GDC) contains more than 2.9 petabytes of genomic and associated clinical data from more than 60 NCI-funded and other contributed cancer genomics research projects. The GDC consists of five app