Výsledky vyhledávání - "Ian J. Foulds"

A generalized transducing phage for the murine pathogen Citrobacter rodentium

Autor: David Goulding, Nicola K. Petty, Ian J. Foulds, Ana Luisa Toribio, Gordon Dougan, George P. C. Salmond, Nicholas R. Thomson

Publikováno v: Microbiology. 153:2984-2988

A virulent phage (φCR1) capable of generalized transduction in Citrobacter rodentium was isolated from the environment and characterized. C. rodentium is a natural pathogen of mice, causing transmissible murine colonic hyperplasia. Sequencing of its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea853ffc76da7c435a777d41d83b5d5
https://doi.org/10.1099/mic.0.2007/008888-0

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A generalized transducing phage (ϕIF3) for the genomically sequenced Serratia marcescens strain Db11: a tool for functional genomics of an opportunistic human pathogen

Autor: George P. C. Salmond, Jonathan J. Ewbank, Nicola K. Petty, Ian J. Foulds, Elizabeth Pradel

Publikováno v: Microbiology. 152:1701-1708

A bacteriophage (ϕIF3) capable of mediating generalized transduction in Serratia marcescens strain Db11 has been isolated and characterized. The genome of this Serratia strain has recently been sequenced and is likely to become the reference strain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cce3b67928bcba41b55e3d8586f26c5
https://doi.org/10.1099/mic.0.28712-0

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The Pseudomonas aeruginosa generalized transducing phage phiPA3 is a new member of the phiKZ-like group of 'jumbo' phages, and infects model laboratory strains and clinical isolates from cystic fibrosis patients

Autor: Ian J. Foulds, George P. C. Salmond, Martin Welch, J. Foweraker, Rita E. Monson

Publikováno v: Microbiology (Reading, England). 157(Pt 3)

Pseudomonas aeruginosa is an important pathogen in cystic fibrosis patients, and a model organism for the study of nosocomially acquired infections, biofilms and intrinsic multidrug resistance. In this study we characterize φPA3, a new generalized t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8b7d329de0feb7078f8e0ad12be743
https://pubmed.ncbi.nlm.nih.gov/21163841

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The phage abortive infection system, ToxIN, functions as a protein-RNA toxin-antitoxin pair

Autor: Tim R. Blower, George P. C. Salmond, Kathryn S. Lilley, Peter C. Fineran, Ian J. Foulds, David P. Humphreys

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 106(3)

Various mechanisms exist that enable bacteria to resist bacteriophage infection. Resistance strategies include the abortive infection (Abi) systems, which promote cell death and limit phage replication within a bacterial population. A highly effectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7f9e087db413ee03e25eb28ccfddc9
https://pubmed.ncbi.nlm.nih.gov/19124776

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Regions of an Eimeria tenella antigen contain sequences which are conserved in circumsporozoite proteins from Plasmodium spp. and which are related to the thrombospondin gene family

Autor: Martin H. Wisher, Ian J. Foulds, Mike Boursnell, Fiona M. Tomley, Lorraine Elisabeth Clarke

Publikováno v: Molecular and Biochemical Parasitology. 41:269-279

Coccidiosis, caused by Eimeria spp., is a major disease of economic importance to the poultry industry. The cloning and characterisation of genes coding for antigens of those species infecting chickens is an initial step in the identification of prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0831db796580427803b9a1b0722a581e
https://doi.org/10.1016/0166-6851(90)90190-w

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Quorum sensing has an unexpected role in virulence in the model pathogen Citrobacter rodentium

Autor: Sarah J. Coulthurst, George P. C. Salmond, Gordon Dougan, Terry John Evans, Martin Welch, Kevin J. Roberts, Simon Clare, Ian J. Foulds

Publikováno v: EMBO reports. 8(7)

The bacterial mouse pathogen Citrobacter rodentium causes attaching and effacing (AE) lesions in the same manner as pathogenic Escherichia coli, and is an important model for this mode of pathogenesis. Quorum sensing (QS) involves chemical signalling

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb298c1c0267909e5c9b9b5085712f0
https://pubmed.ncbi.nlm.nih.gov/17557113

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The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species- and strain-dependent genome context variation

Autor: Anthony Cox, Neil R. Williamson, Sophia Abbasi, Abigail K. P. Harris, Finian J. Leeper, Ian J. Foulds, Henrik Toft Simonsen, Holly Slater, George P. C. Salmond

Publikováno v: Microbiology (Reading, England). 150(Pt 11)

The prodigiosin biosynthesis gene cluster (pigcluster) from two strains ofSerratia(S. marcescensATCC 274 andSerratiasp. ATCC 39006) has been cloned, sequenced and expressed in heterologous hosts. Sequence analysis of the respectivepigclusters reveale

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d056517f21acec0fa41f84a0e498438
https://pubmed.ncbi.nlm.nih.gov/15528645

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