Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ian Huck"'
Autor:
Anit Shah, Ian Huck, Kaylia Duncan, Erica R. Gansemer, Udayan Apte, Mark A. Stamnes, D. Thomas Rutkowski
Publikováno v:
bioRxiv
In all eukaryotic cell types, the unfolded protein response (UPR) upregulates factors that promote protein folding and misfolded protein clearance to help alleviate endoplasmic reticulum (ER) stress. Yet ER stress in the liver is uniquely accompanied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bcf04abed3696da0817e349b47200b3
https://doi.org/10.1101/2023.02.09.527889
https://doi.org/10.1101/2023.02.09.527889
Publikováno v:
Gene Expr
Hepatocyte nuclear factor 4 alpha (HNF4) is required for hepatocyte differentiation and regulates expression of genes involved in lipid and carbohydrate metabolism including those that control VLDL secretion and gluconeogenesis. Whereas previous stud
Autor:
Ian Huck, Kari Nejak-Bowen, Aaron Bell, Udayan Apte, Minakshi Poddar, Sarangarajan Ranganathan, Satdarshan P.S. Monga, Sungjin Ko, Tirthadipa Pradhan-Sundd, Sucha Singh, Donna B. Stolz, Jonathan Franks, Silvia Liu
Publikováno v:
Am J Pathol
Hepatocytes are highly polarized epithelia. Loss of hepatocyte polarity is associated with various liver diseases, including cholestasis. However, the molecular underpinnings of hepatocyte polarization remain poorly understood. Loss of β-catenin at
Autor:
Lilley Leong, Tony Byun, Benjamin Kim, Ian Huck, Abel Silva, Joanne Chan, Young Cho, John Liu, Christopher J. Horvath, Stephen J. Moore, Sandip Panicker
Publikováno v:
Blood. 140:1666-1667
Autor:
Eileen Rose, Stephen J. Moore, Allen Cai, Alina He, Ian Huck, Jen Razo, Laurie Wong, Joanne Chan, Christopher J. Horvath, John Liu, Sandip Panicker
Publikováno v:
Blood. 140:8318-8319
Autor:
Gisela Geoghegan, Helaina Von Bank, Raghav Jain, Paula Gonzalez, Mae Hurtado-Thiele, Charlie Kirsh, Ian Huck, Udayan Apte, Alan Attie, Mark Keller, Judith Simcox
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
Hepatology
Hepatocyte nuclear factor 4 alpha (HNF4α) is indispensable for hepatocyte differentiation and critical for maintaining liver health. Here we demonstrate that loss of HNF4α activity is crucial step in pathogenesis of chronic liver diseases that lead
Publikováno v:
International Journal of Toxicology. 37:383-392
Perfluorooctanesulfonic acid (PFOS) is a persistent organic pollutant with worldwide bioaccumulation due to a very long half-life. Perfluorooctanesulfonic acid exposure results in significant hepatic effects including steatosis, proliferation, hepato
Autor:
Blaise Menta, Chad Slawson, Natasha E. Zachara, Khyati Dalal, Maura O'Neil, Steven R. McGreal, Ian Huck, Sumedha Gunewardena
Publikováno v:
The FASEB Journal. 33
Hepatocyte Nuclear Factor 4 alpha (HNF4α) is required for hepatocyte differentiation and regulates expression of genes involved in lipid and carbohydrate metabolism including those that control VLDL secretion and gluconeogenesis. Whereas previous st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1198acad4f87b06fb7c49b18927e86bc
https://doi.org/10.1101/401802
https://doi.org/10.1101/401802