Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Ian H. Johnston"'
Autor:
Carlos H. Villa, Daniel C. Pan, Ian H. Johnston, Colin F. Greineder, Landis R. Walsh, Elizabeth D. Hood, Douglas B. Cines, Mortimer Poncz, Don L. Siegel, Vladimir R. Muzykantov
Publikováno v:
Blood Advances, Vol 2, Iss 3, Pp 165-176 (2018)
Abstract: Carriage of drugs by red blood cells (RBCs) modulates pharmacokinetics, pharmacodynamics, and immunogenicity. However, optimal targets for attaching therapeutics to human RBCs and adverse effects have not been studied. We engineered nonhuma
Externí odkaz:
https://doaj.org/article/a2921fc5daff4bd8bbb9bbefa4a0a492
Autor:
Colin F. Greineder, Ian H. Johnston, Carlos H. Villa, Kandace Gollomp, Charles T. Esmon, Douglas B. Cines, Mortimer Poncz, Vladimir R. Muzykantov
Publikováno v:
Blood Advances, Vol 1, Iss 18, Pp 1452-1465 (2017)
Abstract: Diverse human illnesses are characterized by loss or inactivation of endothelial thrombomodulin (TM), predisposing to microvascular inflammation, activation of coagulation, and tissue ischemia. Single-chain antibody fragment (scFv)/TM) fusi
Externí odkaz:
https://doaj.org/article/5eaf34428b9e4bf6807c10cf61c2e8ce
Autor:
Rohit K. Gupte, Lawrence A. Sasso, Akif Ündar, Ian H. Johnston, Jeffrey D. Zahn, Mingde Zheng
Publikováno v:
Microfluidics and nanofluidics. 13(4)
A microfluidic platform is presented which fully automates all incubation steps of a three-stage, multiplexed magnetic bead immunoassay, such as the Luminex® xMAP technology. Magnetic actuation is used to transfer the microbeads between co-infused a
Publikováno v:
British Journal of Neurosurgery. 8:377-380
A case of a 14-year-old boy with syndactyly of all limbs and intracranial dural arteriovenous malformation (AVM) is presented. A failure of differentiation of cerebral vessels, possibly at 3 weeks gestational age, is discussed along with several alte
Publikováno v:
Neuro-Ophthalmology. 12:193-196
The authors report two patients with shunted hydrocephalus who developed features of the pretectal syndrome in association with shunt dysfunction but without any dilatation of the ventricular system and no detected elevation of intracranial pressure
Publikováno v:
Neurosurgery. 29:832-837
Patients considered to have a possible disorder of the circulation of the cerebrospinal fluid (CSF) were prospectively randomized on clinical and computed tomographic grounds into one of four categories: low probability of a disorder of circulation o
Autor:
Martin McGee-Collett, Ian H Johnston
Publikováno v:
Medical Journal of Australia. 155:14-17
Objective To examine the presentation, investigative findings, treatment and outcome in patients with spinal epidural abscess. Design and setting The study was a retrospective analysis of all patients with this condition presenting to the Neurosurgic
Publikováno v:
Journal of Clinical Neuroscience. 6:375-377
The effect of optic nerve sheath decompression (ONSD) on cerebrospinal fluid (CSF) pressure and outflow resistance was studied in six patients who underwent the procedure (four unilateral, two bilateral) for papilloedema secondary to raised intracran
Publikováno v:
Journal of Clinical Neuroscience. 4:352-354
Membranous aqueduct occlusion is one of the few causes of obstructive hydrocephalus that is amenable to direct surgical treatment. Conventional diagnostic methods may not delineate this entity. The advent of dynamic fast multiphase magnetic resonance
Publikováno v:
Pediatric neurosurgery. 34(2)
Twelve patients are described who were found to have asymptomatic intracranial hypertension monitored over an extended (6 months to 6 years) period. There were three groups: 5 patients with treated hydrocephalus with an apparently functioning shunt,