Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Ian H, Harding"'
Autor:
Sirio Cocozza, Sara Bosticardo, Matteo Battocchio, Louise Corben, Martin Delatycki, Gary Egan, Nellie Georgiou‐Karistianis, Serena Monti, Giuseppe Palma, Chiara Pane, Francesco Saccà, Simona Schiavi, Louisa Selvadurai, Mario Tranfa, Alessandro Daducci, Arturo Brunetti, Ian H. Harding
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 7, Pp 1691-1702 (2024)
Abstract Objective The dentato‐thalamo‐cortical tract (DTT) is the main cerebellar efferent pathway. Degeneration of the DTT is a core feature of Friedreich ataxia (FRDA). However, it remains unclear whether DTT disruption is spatially specific,
Externí odkaz:
https://doaj.org/article/d4eb1b573f2a4570a1fdf5b47c296bef
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 4, Pp 989-999 (2024)
Abstract Objective Huntington's disease (HD) is an inherited neurodegenerative disease involving progressive motor abnormalities, cognitive decline, and psychiatric disturbances. Depression and cognitive difficulties are among the most impactful symp
Externí odkaz:
https://doaj.org/article/871d1e7b69a6439a97efe08a56f4b870
Autor:
Helmut Butzkueven, Kelly L Bertram, Lucy Vivash, Dominic Thyagarajan, Terence J O’Brien, Ian H Harding, Timothy P Siejka, Huiliang M Tang
Publikováno v:
BMJ Neurology Open, Vol 6, Iss 1 (2024)
Introduction Atypical parkinsonian syndromes (APS) are rare neurodegenerative syndromes for which parkinsonism is one significant feature. APS includes progressive supranuclear palsy (PSP), multiple system atrophy (MSA) and corticobasal syndrome (CBS
Externí odkaz:
https://doaj.org/article/53fe9fe1240842858b2dd72c67a544ee
Autor:
Ella Rowsthorn, William Pham, Mohammad-Reza Nazem-Zadeh, Meng Law, Matthew P. Pase, Ian H. Harding
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-21 (2023)
Abstract The neurovascular unit (NVU) is a complex structure that facilitates nutrient delivery and metabolic waste clearance, forms the blood–brain barrier (BBB), and supports fluid homeostasis in the brain. The integrity of NVU subcomponents can
Externí odkaz:
https://doaj.org/article/b362bef7eeb343d8928d52d378b905d2
Autor:
Sharon L Naismith, Craig S Anderson, Stephane Heritier, Michael O'Sullivan, Sophia Zoungas, Joanne Ryan, Ian H Harding, Simone Spark, Meng Law, Trevor T-J Chong, Zachary Flanagan, Richard McIntyre, Gary Egan
Publikováno v:
BMJ Neurology Open, Vol 5, Iss 2 (2023)
Introduction Cerebrovascular disease and neurodegeneration are causes of cognitive decline and dementia, for which primary prevention options are currently lacking. Statins are well-tolerated and widely available medications that potentially have neu
Externí odkaz:
https://doaj.org/article/354bf56a16ec4b679cb93a417690ab8c
Autor:
Thang Ngo, Pubudu N. Pathirana, Malcolm K. Horne, Louise A. Corben, Ian H. Harding, David J. Szmulewicz
Publikováno v:
IEEE Access, Vol 11, Pp 14006-14027 (2023)
Cerebellar ataxia is the poorly coordinated movement that results from injury or disease affecting the cerebellum. The diagnosis and assessment of ataxia are significantly challenging due to dependency on clinicians’ experience and the attendant su
Externí odkaz:
https://doaj.org/article/73f41419ae8540259e73ef8e90fcc893
Autor:
Christian Rummey, Ian H. Harding, Martin B. Delatycki, Geneieve Tai, Thiago Rezende, Louise A. Corben
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 12, Pp 2041-2046 (2022)
Abstract The ever‐increasing body of ataxia research provides opportunities for large‐scale meta‐analyses, systematic reviews, and data aggregation. Because multiple standardized scales are used to quantify ataxia severity, harmonization of the
Externí odkaz:
https://doaj.org/article/2cd3ff91185b42b999860cbeb6558b8f
Publikováno v:
Brain Sciences, Vol 13, Iss 11, p 1552 (2023)
Parkinson’s Disease (PD) has historically been considered a disorder of motor dysfunction. However, a growing number of studies have demonstrated sensory abnormalities in PD across the modalities of proprioceptive, tactile, visual, auditory and tem
Externí odkaz:
https://doaj.org/article/143527696dc846028d1e2dce11be7b93
Autor:
Jo Wrigglesworth, Joanne Ryan, Phillip G. D. Ward, Robyn L. Woods, Elsdon Storey, Gary F. Egan, Anne Murray, Sara E. Espinoza, Raj C. Shah, Ruth E. Trevaks, Stephanie A. Ward, Ian H. Harding
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2023)
IntroductionNeuroimaging-based ‘brain age’ can identify individuals with ‘advanced’ or ‘resilient’ brain aging. Brain-predicted age difference (brain-PAD) is predictive of cognitive and physical health outcomes. However, it is unknown how
Externí odkaz:
https://doaj.org/article/81db835b3e66491aac7dd02caf1c8d6b
Publikováno v:
Harvard Data Science Review, Vol 6, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/f3b618f6d7674a77918661382e2e02c7