Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Ian H, Gilbert"'
Autor:
Franz S Gruber, Anthony Richardson, Zoe C Johnston, Rachel Myles, Neil R Norcross, David P Day, Irene Georgiou, Laura Sesma-Sanz, Caroline Wilson, Kevin D Read, Sarah Martins da Silva, Christopher L R Barratt, Ian H Gilbert, Jason R Swedlow
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0297666 (2024)
Male contraceptive options and infertility treatments are limited, and almost all innovation has been limited to updates to medically assisted reproduction protocols and methods. To accelerate the development of drugs that can either improve or inhib
Externí odkaz:
https://doaj.org/article/f2f5d29a721e4ad38c065b5e3404a1c2
Design of the Global Health chemical diversity library v2 for screening against infectious diseases.
Autor:
Caroline Wilson, J Mark F Gardner, David W Gray, Beatriz Baragana, Paul G Wyatt, Alex Cookson, Stephen Thompson, Cesar Mendoza-Martinez, Michael J Bodkin, Ian H Gilbert, Gary J Tarver
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 12, p e0011799 (2023)
There is a need for novel chemical matter for phenotypic and target-based screens to find starting points for drug discovery programmes in neglected infectious diseases and non-hormonal contraceptives that disproportionately affect Low- and Middle-In
Externí odkaz:
https://doaj.org/article/ae7dc23b661c42e4b35f3b3a4b1a1f7f
Autor:
Abi Manesh, Chaitra Shankar, Mithun M. George, Davinder S. Jasrotia, Binesh Lal, Biju George, Vikram Mathews, C. E. Eapen, Philip Joseph, K. Subramani, Shoma Rao, John V. Peter, Binila Chacko, Anand Zachariah, Sowmya Sathyendra, Samuel G. Hansdak, Ooriapadickal C. Abraham, Ramya Iyadurai, Saranya Vijayakumar, Rajiv Karthik, Charis A. Marwick, Benjamin J. Parcell, Ian H. Gilbert, Balaji Veeraraghavan, George M. Varghese
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 5, Pp 1319-1335 (2023)
Abstract Introduction The objective of this study was to examine the evolution of carbapenem-resistant Klebsiella pneumoniae (CRKp) infections and their impact at a tertiary care hospital in South India. Methods A comparative analysis of clinical dat
Externí odkaz:
https://doaj.org/article/12dfbb4c20ea4b0f9d7f264567f0419f
Autor:
Simon R. Green, Susan H. Davis, Sebastian Damerow, Curtis A. Engelhart, Michael Mathieson, Beatriz Baragaña, David A. Robinson, Jevgenia Tamjar, Alice Dawson, Fabio K. Tamaki, Kirsteen I. Buchanan, John Post, Karen Dowers, Sharon M. Shepherd, Chimed Jansen, Fabio Zuccotto, Ian H. Gilbert, Ola Epemolu, Jennifer Riley, Laste Stojanovski, Maria Osuna-Cabello, Esther Pérez-Herrán, María José Rebollo, Laura Guijarro López, Patricia Casado Castro, Isabel Camino, Heather C. Kim, James M. Bean, Navid Nahiyaan, Kyu Y. Rhee, Qinglan Wang, Vee Y. Tan, Helena I. M. Boshoff, Paul J. Converse, Si-Yang Li, Yong S. Chang, Nader Fotouhi, Anna M. Upton, Eric L. Nuermberger, Dirk Schnappinger, Kevin D. Read, Lourdes Encinas, Robert H. Bates, Paul G. Wyatt, Laura A. T. Cleghorn
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Tuberculosis is a major cause of mortality, and the rise of drug-resistant strains of Mycobacterium tuberculosis requires the urgent development of safe and effective treatments. In this work, the authors develop a compound against lysyl-tRNA synthet
Externí odkaz:
https://doaj.org/article/3aefb9dc25794e5b8cda7dfd998654ed
Autor:
Paul Kelly, William A Petri, Rashidul Haque, Ibrahim A Khalil, Lynn Barrett, Tom Kennedy, Timothy Wells, Christopher D Huston, James Platts-mills, Grace S Yang, Richard Omore, Ian H Gilbert, Sumiti Vinayak, Boris Striepen, Ujjini H Manjunatha, Wesley C Van Voorhis, Samuel L M Arnold, Beatriz Baragana, Frederick S Buckner, Jeremy D Burrows, Maria A Caravedo, Ryan Choi, Robert K M Choy, Eugenio de Hostos, Thierry Diagana, Suzanne Duce, Matthew A Hulverson, Pui-Ying Iroh Tam, Minju Kim, Poonum Korpe, Benoît Laleu, Diana Lalika, Fabrice Laurent, Case W McNamara, Marvin J Meyers, Roberta M O’Connor, Kayode K Ojo, Philipp Olias, Nede Ovbiebo, Mattie C Pawlowic, Gladys Queen, Divya Rao, Kevin Reed, Michael W Riggs, Jennifer L Roxas, Adam Sateriale, Deborah A Schaefer, L David Sibley, Jonathan M Spector, Chris Tonkin, Timilehin E Toye, Saul Tzipori, A Clinton White
Publikováno v:
BMJ Global Health, Vol 8, Iss 8 (2023)
Externí odkaz:
https://doaj.org/article/540e409047fd43baae051b1737c1bbc5
Publikováno v:
ACS Omega, Vol 4, Iss 21, Pp 19199-19215 (2019)
Externí odkaz:
https://doaj.org/article/9bf99d26e3b0414497b42aa0e2805981
Autor:
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L. Bustinduy, Conor R. Caffrey, James J. Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F. Hoffmann, Michael Hsieh, Nathan C. Lo, Case W. McNamara, Justin Komguep Nono, Gilda Padalino, Kevin D. Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H. Gilbert
Publikováno v:
ACS Infectious Diseases. 9:1046-1055
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef56205a89b9183d45c0d37e1c82e2e6
https://doi.org/10.1021/acsinfecdis.3c00081
https://doi.org/10.1021/acsinfecdis.3c00081
Publikováno v:
ACS Omega. 8:15083-15098
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3828b6af71e58964fed8b5e1fc1d1d4f
https://doi.org/10.1021/acsomega.2c08132
https://doi.org/10.1021/acsomega.2c08132
Autor:
James S. Martin, Claire J. Mackenzie, De Lin, Nadine Homeyer, David W. Gray, Fabio Zuccotto, Ian H. Gilbert
Publikováno v:
ACS Omega. 8:12787-12804
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ce02eeb04ff7b9d23bcab7c2b09d305
https://doi.org/10.1021/acsomega.2c08031
https://doi.org/10.1021/acsomega.2c08031
Autor:
Irene Hallyburton, Raffaella Grimaldi, Andrew Woodland, Beatriz Baragaña, Torsten Luksch, Daniel Spinks, Daniel James, Didier Leroy, David Waterson, Alan H. Fairlamb, Paul G. Wyatt, Ian H. Gilbert, Julie A. Frearson
Publikováno v:
Malaria Journal, Vol 16, Iss 1, Pp 1-11 (2017)
Abstract Background Protein kinases have been shown to be key drug targets, especially in the area of oncology. It is of interest to explore the possibilities of protein kinases as a potential target class in Plasmodium spp., the causative agents of
Externí odkaz:
https://doaj.org/article/566b9ef7b74a4082b406a4a2a9e0d020