A novel suprachoroidal microinvasive glaucoma implant: in vivo biocompatibility and biointegration

Autor: Ian Grierson, Don Minckler, Marian K. Rippy, Andrew J. Marshall, Nathalie Collignon, Jessica Bianco, Benoit Detry, Murray A. Johnstone

Publikováno v: BMC Biomedical Engineering, Vol 2, Iss 1, Pp 1-11 (2020)

Abstract Background A major challenge for any glaucoma implant is their ability to provide long-term intraocular pressure lowering efficacy. The formation of a low-permeability fibrous capsule around the device often leads to obstructed drainage chan

Externí odkaz: https://doaj.org/article/4117436b38934b1b887feb5b94ffe59e

Dishes with Strange Names : Traditional British and Irish Food

Autor: Ian Grierson

British and Irish cuisine, rich in tradition and flavour, has faced challenges in adapting to the modern world. Renowned for its hearty ingredients and lengthy cooking times, this style of cooking often clashes with today's fast-paced lifestyle, wher

Advanced glycation end products-related modulation of cathepsin L and NF-kappa B signalling effectors in retinal pigment epithelium lead to augmented response to TNF alpha

Autor: Yit C. Yang, Paul Kay, Tengku Ain Kamalden, Malcolm J. Jackson, Ian Grierson, Nur Musfirah Mahmud, Simon P. Harding, Umar Sharif, Luminita Paraoan

Publikováno v: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Journal of Cellular and Molecular Medicine

The retinal pigment epithelium (RPE) plays a central role in neuroretinal homoeostasis throughout life. Altered proteolysis and inflammatory processes involving RPE contribute to the pathophysiology of age‐related macular degeneration (AMD), but th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e686b55e0374687a44cff25a926447
http://livrepository.liverpool.ac.uk/3027851/1/CathepsinsNFkB-2018-JCMM.pdf

Clinical efficacy and safety of a light mask for prevention of dark adaptation in treating and preventing progression of early diabetic macular oedema at 24 months (CLEOPATRA): a multicentre, phase 3, randomised controlled trial

Autor: Randhir Chavan, S J Aldington, Arevik Ghulakhszian, Roxanne Crosby-Nwaobi, Richard D. Smith, Priya Prakash, Edward Hughes, Geoffrey B. Arden, Debendra N. Sahu, Sarah Walker, Alaistair Denniston, Jackie Sturt, Nirodhini Narendran, Nisha Shah, Abosede Cole, Sobha Sivaprasad, Haralabos Eleftheriadis, Joanna Kelly, Peter H Scanlon, Afsar Jafree, Sheena George, Tatiana Mansour, S Chave, A Dale, Tunde Peto, Namritha Patrao, A Toby Prevost, Ajay Bhatnagar, Joana C. Vasconcelos, Philip Hykin, Douglas Lewin, Gary S. Rubin, Chris Hogg, Caroline Murphy, Gilli Vafidis, Maria Sandinha, Frank Ahfat, Geeta Menon, David P. Crabb, Catherine A Egan, Gillian Hood, Joanathan Gibson, Graham A. Hitman, Ian Grierson, Helen Holmes, Deepthy Menon, Lauren Leitch-Devlin

Publikováno v: Sivaprasad, S, Vasconcelos, J C, Prevost, A T, Holmes, H, Hykin, P, George, S, Murphy, C, Kelly, J, Arden, G B, CLEOPATRA Study Group & Peto, T 2018, ' Clinical efficacy and safety of a light mask for prevention of dark adaptation in treating and preventing progression of early diabetic macular oedema at 24 months (CLEOPATRA): a multicentre, phase 3, randomised controlled trial ', The lancet. Diabetes & endocrinology . https://doi.org/10.1016/S2213-8587(18)30036-6
The Lancet. Diabetes & Endocrinology

BACKGROUND: We aimed to assess 24-month outcomes of wearing an organic light-emitting sleep mask as an intervention to treat and prevent progression of non-central diabetic macular oedema.METHODS: CLEOPATRA was a phase 3, single-blind, parallel-group

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da900962587753965c9a5f4b04bd3ca1
http://hdl.handle.net/10044/1/71846

Safety and acceptability of an organic light-emitting diode sleep mask as a potential therapy for retinal disease

Autor: Kate M. Bennett, Jayashree Sahni, Ian Grierson, C Murray-Dunning, S A Taylor, Sophie Wuerger, T Gutu, Simon P. Harding, M N Holland, Gabriela Czanner

Publikováno v: Eye

Purpose The purpose of the study was to study the effect of an organic light-emitting diode sleep mask on daytime alertness, wellbeing, and retinal structure/function in healthy volunteers and in diabetic macular oedema (DMO). Patients and methods He

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf64fb829bda1497a0f5777efab4162
http://livrepository.liverpool.ac.uk/3005681/1/eye2016259a.pdf