Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ian Gabbott"'
Autor:
Catherine N. Hallam, Ian Gabbott
Publikováno v:
Journal of Drug Delivery Science and Technology. 52:825-830
The effect of milled extrudate particle size on tablet tensile strength was investigated in this study. Parameters used for milling with a hammer impact mill were investigated to give different particle size milled extrudate. Mill screen type and ape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f2d62f28b0ee831c6104d48489dd74e
https://doi.org/10.1016/j.jddst.2019.05.049
https://doi.org/10.1016/j.jddst.2019.05.049
Autor:
Ian Gabbott, Agba D. Salman, Gavin K. Reynolds, Ronald John Roberts, Bilal Khorsheed, Stefan C. Taylor
Publikováno v:
Powder Technology. 341:104-115
Granulation is a technique commonly used before tabletting because it solves powder handling problems and ensures uniform filling of the compression dies. However, granulation can have an adverse impact on powder transformation into a tablet; i.e. ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b72d3bdd8a33ff6ac42d2d0fa83f5e7
https://doi.org/10.1016/j.powtec.2018.05.013
https://doi.org/10.1016/j.powtec.2018.05.013
Publikováno v:
Journal of Drug Delivery Science and Technology. 46:1-6
The effect of tablet tensile strength, drop height, number of drops and formulation on the propensity of tablet defects was investigated using modified tablet drop tests. It was found that increased drop height and number of drops increase the likeli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::130f0aaf4b01534056b4c04b5b57aba0
https://doi.org/10.1016/j.jddst.2018.04.020
https://doi.org/10.1016/j.jddst.2018.04.020
Autor:
Stuart C. Porter, Stephanie Sido, Ronald Hach, Daniel Niblett, Jennifer Greenamoyer, Tomos Morgan, Kapish Karan, Ian Gabbott, Gavin P. Reynolds
Publikováno v:
International Journal of Pharmaceutics. 528:180-201
A mathematical, mechanistic tablet film-coating model has been developed for pharmaceutical pan coating systems based on the mechanisms of atomisation, tablet bed movement and droplet drying with the main purpose of predicting tablet appearance quali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f262f5e1c9b076a5fbf42b94f489f89
https://doi.org/10.1016/j.ijpharm.2017.05.060
https://doi.org/10.1016/j.ijpharm.2017.05.060
Autor:
Marcel de Matas, Neil A. Rowson, Gavin K. Reynolds, Tim Chan Seem, Ian Gabbott, Andrew Ingram
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 106:50-58
Positron Emission Particle Tracking (PEPT) was successfully employed to validate measured transverse asymmetry in material distribution in the conveying zones of a Twin Screw Granulator (TSG). Flow asymmetry was established to be a property of the gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2258480d7d99c2cd4043195ad4307bcd
https://doi.org/10.1016/j.ejpb.2016.01.013
https://doi.org/10.1016/j.ejpb.2016.01.013
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 106:70-78
A pharmaceutical compound was used to study the effect of batch wet granulation process parameters in combination with the residual moisture content remaining after drying on granule and tablet quality attributes. The effect of three batch wet granul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b0945cd217b67f224bda5291464a0d
https://doi.org/10.1016/j.ejpb.2016.03.022
https://doi.org/10.1016/j.ejpb.2016.03.022
Publikováno v:
Journal of Drug Delivery Science and Technology. 55:101335
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::371eb54ced84ceb9a30f11c6e7c16eb4
https://doi.org/10.1016/j.jddst.2019.101335
https://doi.org/10.1016/j.jddst.2019.101335
Autor:
Gavin K. Reynolds, Shankali U. Pradhan, Jiayu Li, Maitraye Sen, Ian Gabbott, Carl Wassgren, James D. Litster
Publikováno v:
Drug development and industrial pharmacy. 44(11)
This work examines the influence of pharmaceutical powder formulation characteristics on granule properties formed using distributive mixing elements (DMEs) in twin screw granulation. High and low drug dose formulations with three different active ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a5b2dc343db8c1b7fc47893f0705714
https://pubmed.ncbi.nlm.nih.gov/30027770
https://pubmed.ncbi.nlm.nih.gov/30027770
Autor:
Ian Gabbott, Shen Yu, Neil A. Rowson, Zhenyu Huang, Gavin K. Reynolds, Timothy Chan Seem, Andrew Ingram, Marcel de Matas
Publikováno v:
Powder Technology. 276:89-102
This review article addresses the currently available literature on twin screw granulation (TSG). TSG is an emerging technology rapidly gaining interest in the pharmaceutical industry as a method of continuous wet granulation. The control of the geom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec47112fed275cf3e8b27f6e5972d08a
https://doi.org/10.1016/j.powtec.2015.01.075
https://doi.org/10.1016/j.powtec.2015.01.075
Autor:
Ian Gabbott, Gavin K. Reynolds, Agba D. Salman, Bilal Khorsheed, Wafa' H. AlAlaween, Mahdi Mahfouf
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 124
In this research, a new systematic modelling framework which uses machine learning for describing the granulation process is presented. First, an interval type-2 fuzzy model is elicited in order to predict the properties of the granules produced by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bbb060f6168fd863d91e97b254e08ea
https://pubmed.ncbi.nlm.nih.gov/29288806
https://pubmed.ncbi.nlm.nih.gov/29288806