Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Ian G. Young"'
Autor:
Charmaine J. Simeonovic, Michelle J. Townsend, Gunasegaran Karupiah, J. Dennis Wilson, Jodie C. Zarb, David A. Mann, Ian G. Young
Publikováno v:
Cell Transplantation, Vol 8 (1999)
The rejection mechanisms for fetal proislet allografts and pig proislet xenografts in mice are characterized by different intragraft cytokine mRNA profiles and cellular responses. Allograft rejection is predominantly CD8 T-cell-dependent and is assoc
Externí odkaz:
https://doaj.org/article/e29cb3efeaff4a2694a407193fa8a595
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 92, Pp 63-68 (1997)
Eosinophil recruitment is a characteristic feature of a number of pathological conditions and was the topic of the recent International Symposium on allergic inflammation, asthma, parasitic and infectious diseases (Rio de Janeiro, June 3-5, 1996). Si
Externí odkaz:
https://doaj.org/article/16392b0d24304d9fbcdf7085cbf86979
Autor:
Paul D. Carr, James M. Murphy, Jin Dai, David L. Ollis, Colin J. Jackson, Cameron L. Ewens, Ian G. Young
Publikováno v:
Biochemical Journal. 463:393-403
Interleukin-3 (IL-3) is a cytokine secreted by mast cells and activated T-cells known to be an important regulator of differentiation, survival, proliferation and activation of a range of haemopoietic lineages. The effects of IL-3 on target cells are
Publikováno v:
Biochemistry. 50:2464-2477
Interleukin-3 (IL-3), a cytokine produced primarily by activated T-cells during immune responses, is a crucial regulator of allergic inflammation. The three-dimensional structure of murine IL-3 (mIL-3) has remained elusive owing to its poor solubilit
Autor:
Bin Wen, James M. Murphy, Jin Dai, Jinglong Chen, Cameron L. Ewens, Shamaruh Mirza, Ian G. Young
Publikováno v:
Journal of Biological Chemistry. 285:22370-22381
The cytokine interleukin-3 (IL-3) is a critical regulator of inflammation and immune responses in mammals. IL-3 exerts its effects on target cells via receptors comprising an IL-3-specific alpha-subunit and common beta-subunit (beta c; shared with IL
Publikováno v:
Growth Factors. 28:104-110
Mouse interleukin-3 (mIL-3) is a critical cytokine regulator of myeloid cell differentiation, survival and activation, and consequently this cytokine has become a key reagent for hematological studies in the laboratory. Although bacterial expression
Autor:
Andrew A. Walker, James M. Murphy, Sally C. Ford, Jinglong Chen, Jane E. Olsen, Shamaruh Mirza, Ian G. Young
Publikováno v:
Journal of Biological Chemistry. 284:5763-5773
Interleukin-3 (IL-3) promotes both self-renewal and differentiation of early multipotential progenitors and is involved in inducible hematopoiesis in response to infections. Here we report new insights into these processes with the identification of
Autor:
Ian G. Young, Jinglong Chen, Shamaruh Mirza, James M. Murphy, Jane E. Olsen, Tatiana A. Soboleva, Sally C. Ford
Publikováno v:
Cytokine. 42:234-242
Granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-3 and IL-5 are related cytokines that play key roles in regulating the differentiation, proliferation, survival and activation of myeloid blood cells. The cell surface recept
Publikováno v:
International Immunology. 18:313-323
IL-5 is a key regulator of eosinophilic inflammation and is selectively expressed by antigen-activated Th2 lymphocytes. An important role for the proximal AP-1 and GATA sites in regulating IL-5 transcription is generally accepted but the significance
Autor:
Sonja E. Gustin, Jane E. Olsen, David L. Ollis, Ian G. Young, James M. Murphy, P.D. Jeffrey, Sally C. Ford
Publikováno v:
Journal of Biological Chemistry. 279:26500-26508
Interleukin-3 (IL-3) is a cytokine produced by activated T-cells and mast cells that is active on a broad range of hematopoietic cells and in the nervous system and appears to be important in several chronic inflammatory diseases. In this study, alan