Zobrazeno 1 - 10
of 636
pro vyhledávání: '"Ian G. Campbell"'
Autor:
Kathleen I. Pishas, Karla J. Cowley, Marta Llaurado-Fernandez, Hannah Kim, Jennii Luu, Robert Vary, Nikola A. Bowden, Ian G. Campbell, Mark S. Carey, Kaylene J. Simpson, Dane Cheasley
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-15 (2024)
Abstract Low grade serous carcinoma (LGSOC) is a rare epithelial ovarian cancer with unique molecular characteristics compared to the more common tubo-ovarian high-grade serous ovarian carcinoma. Pivotal clinical trials guiding the management of epit
Externí odkaz:
https://doaj.org/article/1edb064d2b3943ada492808c792f4438
Autor:
Tanjina Kader, Elena Provenzano, Madawa W. Jayawardana, Shona Hendry, Jia-Min Pang, Kenneth Elder, David J. Byrne, Lauren Tjoeka, Helen ML. Frazer, Eloise House, Sureshni I. Jayasinghe, Holly Keane, Anand Murugasu, Neeha Rajan, Islam M. Miligy, Michael Toss, Andrew R. Green, Emad A. Rakha, Stephen B. Fox, G. Bruce Mann, Ian G. Campbell, Kylie L. Gorringe
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-10 (2024)
Abstract Various histopathological, clinical and imaging parameters have been evaluated to identify a subset of women diagnosed with lesions with uncertain malignant potential (B3 or BIRADS 3/4A lesions) who could safely be observed rather than being
Externí odkaz:
https://doaj.org/article/b48a3f6e9ea54a189ccefd102db6473b
Autor:
Dane Cheasley, Marta Llaurado Fernandez, Martin Köbel, Hannah Kim, Amy Dawson, Joshua Hoenisch, Madison Bittner, Derek S. Chiu, Aline Talhouk, C. Blake Gilks, Madawa W. Jayawardana, Kathleen I. Pishas, Anne-Marie Mes-Masson, Diane Provencher, Abhimanyu Nigam, Neville F. Hacker, Kylie L. Gorringe, Ian G. Campbell, Mark S. Carey
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-8 (2022)
Abstract Hormone receptor expression is a characteristic of low-grade serous ovarian carcinoma (LGSOC). Studies investigating estrogen receptor (ER) and progesterone receptor (PR) expression levels suggest its prognostic and predictive significance,
Externí odkaz:
https://doaj.org/article/c07926245a9a4565975b9f415dbd3ba0
Autor:
Wejdan M. Alenezi, Caitlin T. Fierheller, Corinne Serruya, Timothée Revil, Kathleen K. Oros, Deepak N. Subramanian, Jeffrey Bruce, Dan Spiegelman, Trevor Pugh, Ian G. Campbell, Anne-Marie Mes-Masson, Diane Provencher, William D. Foulkes, Zaki El Haffaf, Guy Rouleau, Luigi Bouchard, Celia M. T. Greenwood, Jiannis Ragoussis, Patricia N. Tonin
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Not all familial ovarian cancer (OC) cases are explained by pathogenic germline variants in known risk genes. A candidate gene approach involving DNA repair pathway genes was applied to identify rare recurring pathogenic variants in familial OC cases
Externí odkaz:
https://doaj.org/article/05d239ab593d4e42b75d51380a913fb1
Autor:
Belle W. X. Lim, Na Li, Simone M. Rowley, Ella R. Thompson, Simone McInerny, Magnus Zethoven, Rodney J. Scott, Lisa Devereux, Erica K. Sloan, Paul A. James, Ian G. Campbell
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-6 (2022)
Abstract While protein-truncating variants in RAD51C have been shown to predispose to triple-negative (TN) breast cancer (BC) and ovarian cancer, little is known about the pathogenicity of missense (MS) variants. The frequency of rare RAD51C MS varia
Externí odkaz:
https://doaj.org/article/cb1b85b7941943879757906ddef2dd42
Autor:
Caitlin T. Fierheller, Laure Guitton-Sert, Wejdan M. Alenezi, Timothée Revil, Kathleen K. Oros, Yuandi Gao, Karine Bedard, Suzanna L. Arcand, Corinne Serruya, Supriya Behl, Liliane Meunier, Hubert Fleury, Eleanor Fewings, Deepak N. Subramanian, Javad Nadaf, Jeffrey P. Bruce, Rachel Bell, Diane Provencher, William D. Foulkes, Zaki El Haffaf, Anne-Marie Mes-Masson, Jacek Majewski, Trevor J. Pugh, Marc Tischkowitz, Paul A. James, Ian G. Campbell, Celia M. T. Greenwood, Jiannis Ragoussis, Jean-Yves Masson, Patricia N. Tonin
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-26 (2021)
Abstract Background Familial ovarian cancer (OC) cases not harbouring pathogenic variants in either of the BRCA1 and BRCA2 OC-predisposing genes, which function in homologous recombination (HR) of DNA, could involve pathogenic variants in other DNA r
Externí odkaz:
https://doaj.org/article/52b67832911d434ca9c1266c56a3622d
Autor:
Na Li, Belle W. X. Lim, Ella R. Thompson, Simone McInerny, Magnus Zethoven, Dane Cheasley, Simone M. Rowley, Michelle W. Wong-Brown, Lisa Devereux, Kylie L. Gorringe, Erica K. Sloan, Alison Trainer, Rodney J. Scott, Paul A. James, Ian G. Campbell
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract Breast cancer (BC) has a significant heritable component but the genetic contribution remains unresolved in the majority of high-risk BC families. This study aims to investigate the monogenic causes underlying the familial aggregation of BC
Externí odkaz:
https://doaj.org/article/91c2f977e91949a284425595f07cfa53
Autor:
Na Li, Magnus Zethoven, Simone McInerny, Lisa Devereux, Yu-Kuan Huang, Niko Thio, Dane Cheasley, Sara Gutiérrez-Enríquez, Alejandro Moles-Fernández, Orland Diez, Tu Nguyen-Dumont, Melissa C. Southey, John L. Hopper, Jacques Simard, Martine Dumont, Penny Soucy, Alfons Meindl, Rita Schmutzler, Marjanka K. Schmidt, Muriel A. Adank, Irene L. Andrulis, Eric Hahnen, Christoph Engel, Fabienne Lesueur, Elodie Girard, Susan L. Neuhausen, Elad Ziv, Jamie Allen, Douglas F. Easton, Rodney J. Scott, Kylie L. Gorringe, Paul A. James, Ian G. Campbell
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract Bi-allelic loss-of-function (LoF) variants in the base excision repair (BER) gene NTHL1 cause a high-risk hereditary multi-tumor syndrome that includes breast cancer, but the contribution of heterozygous variants to hereditary breast cancer
Externí odkaz:
https://doaj.org/article/97871f690ed34ff7804d2d19d439847c
Autor:
Sally M. Hunter, Genevieve V. Dall, Maria A. Doyle, Richard Lupat, Jason Li, Prue Allan, Simone M. Rowley, David Bowtell, On behalf of AOCS, Ian G. Campbell, Kylie L. Gorringe
Publikováno v:
BMC Research Notes, Vol 13, Iss 1, Pp 1-8 (2020)
Abstract Objective Ovarian fibromas and adenofibromas are rare ovarian tumours. They are benign tumours composed of spindle-like stromal cells (pure fibroma) or a mixture of fibroblast and epithelial components (adenofibroma). We have previously show
Externí odkaz:
https://doaj.org/article/b04951423f094474882d7f56bebcc2fa
Autor:
Mei Sim Lung, Catherine A. Mitchell, Maria A. Doyle, Andrew C. Lynch, Kylie L. Gorringe, David D. L. Bowtell, Australian Ovarian Cancer Study Group, Ian G. Campbell, Alison H. Trainer
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Familial cases of appendiceal mucinous tumours (AMTs) are extremely rare and the underlying genetic aetiology uncertain. We identified potential predisposing germline genetic variants in a father and daughter with AMTs presenting
Externí odkaz:
https://doaj.org/article/dd423ce9e9bb43bfa0607007b1b914c2