Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ian Feavers"'
Publikováno v:
Toxins, Vol 11, Iss 7, p 417 (2019)
Whooping cough is caused by the bacterium Bordetella pertussis. There are currently two types of vaccines that can prevent the disease; whole cell vaccines (WCV) and acellular vaccines (ACV). The main virulence factor produced by the organism is pert
Externí odkaz:
https://doaj.org/article/99fe50fd82ad4b04ab1bab4370574aa6
Autor:
Odile B. Harrison, Heike Claus, Ying Jiang, Julia S. Bennett, Holly B. Bratcher, Keith A. Jolley, Craig Corton, Rory Care, Jan T. Poolman, Wendell D. Zollinger, Carl E. Frasch, David S. Stephens, Ian Feavers, Matthias Frosch, Julian Parkhill, Ulrich Vogel, Michael A. Quail, Stephen D. Bentley, Martin C.J. Maiden
Publikováno v:
Emerging Infectious Diseases, Vol 19, Iss 4, Pp 566-573 (2013)
Pathogenic Neisseria meningitidis isolates contain a polysaccharide capsule that is the main virulence determinant for this bacterium. Thirteen capsular polysaccharides have been described, and nuclear magnetic resonance spectroscopy has enabled dete
Externí odkaz:
https://doaj.org/article/0b24a4052f834bb29e0e0c22a5d7d14f
Autor:
Gunnstein Norheim, Holly Sanders, Jardar W Mellesdal, Idunn Sundfør, Hannah Chan, Carina Brehony, Caroline Vipond, Chris Dold, Rory Care, Muhammad Saleem, Martin C J Maiden, Jeremy P Derrick, Ian Feavers, Andrew J Pollard
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0134353 (2015)
Following the introduction of effective protein-polysaccharide conjugate vaccines against capsular group C meningococcal disease in Europe, meningococci of capsular group B remain a major cause of death and can result in debilitating sequelae. The ou
Externí odkaz:
https://doaj.org/article/67c55aa7da9d49dc86024d964d7c99dc
Autor:
Fadil A Bidmos, Hannah Chan, Uta Praekelt, Isfahan Tauseef, Youssif M Ali, Edward B Kaczmarski, Ian Feavers, Christopher D Bayliss
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133855 (2015)
Acquisition of iron from host complexes is mediated by four surface-located receptors of Neisseria meningitidis. The HmbR protein and heterodimeric HpuAB complex bind to haemoglobin whilst TbpBA and LbpBA bind iron-loaded transferrin and lactoferrin
Externí odkaz:
https://doaj.org/article/5552ce05bddd486cb4b1a622464c9d77
Autor:
Ojas H Mehta, Gunnstein Norheim, J Claire Hoe, Christine S Rollier, Jerry C Nagaputra, Katherine Makepeace, Muhammad Saleem, Hannah Chan, David J P Ferguson, Claire Jones, Manish Sadarangani, Derek W Hood, Ian Feavers, Jeremy P Derrick, Andrew J Pollard, E Richard Moxon
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115713 (2014)
Neisseria meningitidis lipopolysaccharide (LPS) has adjuvant properties that can be exploited to assist vaccine immunogenicity. The modified penta-acylated LPS retains the adjuvant properties of hexa-acylated LPS but has a reduced toxicity profile. I
Externí odkaz:
https://doaj.org/article/b2f43a6effa2491b81aa811f86a640d7
Autor:
Manish Sadarangani, J. Claire Hoe, Martin J. Callaghan, Claire Jones, Hannah Chan, Katherine Makepeace, Hélène Daniels-Treffandier, Mary E. Deadman, Christopher Bayliss, Ian Feavers, Peter van der Ley, Andrew J. Pollard
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/40a3ee41a3d94954b8df946c2a8b21f5
Autor:
Manish Sadarangani, J Claire Hoe, Martin J Callaghan, Claire Jones, Hannah Chan, Katherine Makepeace, Hélène Daniels-Treffandier, Mary E Deadman, Christopher Bayliss, Ian Feavers, Peter van der Ley, Andrew J Pollard
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51045 (2012)
Neisseria meningitidis is a major global pathogen causing invasive disease with a mortality of 5-10%. Most disease in developed countries is caused by serogroup B infection, against which there is no universal vaccine. Opacity-associated adhesin (Opa
Externí odkaz:
https://doaj.org/article/d9d297402ad640b4b496acf9462fed84
This concise pocketbook will provide readers with an overview and background of meningococcal disease, treatment options and emerging therapies, and methods of prevention. The book was originally commissioned due to recent developments in vaccination
Autor:
Ian, Feavers, Barry, Walker
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 626
Functional antibody assays can broadly be divided into three categories: neutralisation, serum bactericidal antibody (SBA) and opsonophagocytic assays (OPA). These biological assays are generally more complex than antibody-binding counterparts. They
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::23561bdfa1bc3a79e53381c6fa15d282
https://pubmed.ncbi.nlm.nih.gov/20099130
https://pubmed.ncbi.nlm.nih.gov/20099130
Autor:
Barry, Walker, Ian, Feavers
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 626
Antibody titre is a measure of the presence and amount of antibodies specific to an antigen that are present in the blood. In particular, the titre of an antibody sample is a measure of the antibody concentration determined under a defined set of con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7840526fdea74636040e3345861fb9d
https://pubmed.ncbi.nlm.nih.gov/20099129
https://pubmed.ncbi.nlm.nih.gov/20099129