Zobrazeno 1 - 5
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pro vyhledávání: '"Ian Fallahee"'
Autor:
Ian Fallahee, Daniel Hawiger
Publikováno v:
Antibodies, Vol 13, Iss 1, p 18 (2024)
There is tremendous interest in the production of recombinant proteins, particularly bispecific antibodies and antibody–drug conjugates for research and therapeutic use. Here, we demonstrate a highly versatile plasmid system that allows the rapid g
Externí odkaz:
https://doaj.org/article/a36e6bd057b041febf30973053bf2275
Publikováno v:
Cell reports. 39(2)
It remains unclear how the pro-immunogenic maturation of conventional dendritic cells (cDCs) abrogates their tolerogenic functions. Here, we report that the loss of tolerogenic functions depends on the rapid death of BTLA
Publikováno v:
The Journal of Immunology. 208:54.02-54.02
The recognition of pathogen-associated molecular patterns (PAMPs) through the corresponding pattern recognition receptors (PRRs) induces activation of individual conventional dendritic cells (cDC) in a process often referred to as maturation that res
Autor:
Adeleye, Opejin, Alexey, Surnov, Ziva, Misulovin, Michelle, Pherson, Cindy, Gross, Courtney A, Iberg, Ian, Fallahee, Jessica, Bourque, Dale, Dorsett, Daniel, Hawiger
Publikováno v:
Cell reports
SUMMARY Various processes induce and maintain immune tolerance, but effector T cells still arise under minimal perturbations of homeostasis through unclear mechanisms. We report that, contrary to the model postulating primarily tolerogenic mechanisms
Autor:
Courtney A. Iberg, Ian Fallahee, Daniel Hawiger, Dale Dorsett, Jessica Bourque, Adeleye Opejin, Cindy Gross, Alexey Surnov, Ziva Misulovin, Michelle Pherson
Publikováno v:
Cell Reports. 33:108424
Summary Various processes induce and maintain immune tolerance, but effector T cells still arise under minimal perturbations of homeostasis through unclear mechanisms. We report that, contrary to the model postulating primarily tolerogenic mechanisms