Výsledky vyhledávání - "Ian F. Robey"

Akademický článek

Regulation of the Warburg Effect in Early-Passage Breast Cancer Cells

Autor: Ian F. Robey, Renu M. Stephen, Kathy S. Brown, Brenda K. Baggett, Robert A. Gatenby, Robert J. Gillies

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 8, Pp 745-756 (2008)

Malignancy in cancer is associated with aerobic glycolysis (Warburg effect) evidenced by increased trapping of [18F]deoxyglucose (FdG) in patients imaged by positron emission tomography (PET). [18F]deoxyglucose uptake correlates with glucose transpor

Externí odkaz: https://doaj.org/article/5433340ba8ea4a5f8dbe197be2487884

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Akademický článek

Hypoxia-Inducible Factor-1α and the Glycolytic Phenotype in Tumors

Autor: Ian F. Robey, Anthony D. Lien, Sarah J. Welsh, Brenda K. Baggett, Robert J. Gillies

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 4, Pp 324-330 (2005)

Metastatic tumors generally exhibit aerobic glycolysis (the Warburg effect). The advent of [18F]fluorodeoxyglucose positron emission tomography imaging, coupled with recent findings linking hypoxia-inducible factor (HIF-1α) overexpression to aggress

Externí odkaz: https://doaj.org/article/d5f956cc29ca461aa256562046efb733

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A mathematical model of tumour and blood pHe regulation: The HCO3-/CO2 buffering system

Autor: Natasha K, Martin, Eamonn A, Gaffney, Robert A, Gatenby, Robert J, Gillies, Ian F, Robey, Philip K, Maini

Publikováno v: Mathematical biosciences. 230(1)

Malignant tumours are characterised by a low, acidic extracellular pH (pHe) which facilitates invasion and metastasis. Previous research has proposed the potential benefits of manipulating systemic pHe, and recent experiments have highlighted the pot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8ca56b32889b597ab7887cb18946e49b
https://pubmed.ncbi.nlm.nih.gov/21167185

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Natural and autoantibodies to human T-cell receptor Vbeta segments: potential roles in immunomodulation

Autor: Miranda K, Adelman, Samuel F, Schluter, Ian F, Robey, John J, Marchalonis

Publikováno v: Critical reviews in immunology. 27(3)

Although the manifestation of inflammatory autodestructive disease is the result of major immunological dysfunction, recent evidence indicates that the immune system attempts to compensate by the production of immunomodulatory autoantibodies. Healthy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4ad6057d0cc3906fdd9cfb699bcb0d34
https://pubmed.ncbi.nlm.nih.gov/18197818

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Terminal deoxynucleotidyltransferase deficiency decreases autoimmune disease in diabetes-prone nonobese diabetic mice and lupus-prone MRL-Fas(lpr) mice

Autor: Nora Sarvetnick, Marc S. Horwitz, Luc Teyton, Ian F. Robey, Melissa Peterson, Dwight H. Kono, Ann J. Feeney, Argyrios N. Theofilopoulos, Thomas Stratmann

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 172(7)

The wide diversity of the T and B Ag receptor repertoires becomes even more extensive postneonatally due to the activity of TdT, which adds nontemplated N nucleotides to Ig and TCR coding ends during V(D)J recombination. In addition, complementarity-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce6b08b658041aec4bf6cc5fed5ff1f
https://pubmed.ncbi.nlm.nih.gov/15034081

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