Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ian F. G. King"'
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87714 (2014)
Epidermal Growth Factor Receptor (EGFR) signaling has a conserved role in ethanol-induced behavior in flies and mice, affecting ethanol-induced sedation in both species. However it is not known what other effects EGFR signaling may have on ethanol-in
Externí odkaz:
https://doaj.org/article/db140d8691c14063a07494f56e9a97ad
Autor:
Susan M. Armstrong, Danny Ghazarian, Thiago Pimentel Muniz, Ian F. G. King, Zaid Saeed Kamil, Kendra Ross, Samuel D. Saibil, David Hogg, Anna Spreafico, Marcus O. Butler, Deirdre Kelly, April A.N. Rose, Diana Paola Arteaga
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
PurposeAnti-programmed cell death protein 1 (PD1)±anti-cytotoxic T-lymphocyte associated protein 4 (CTLA4) immune checkpoint inhibitors (ICIs) are standard therapeutic options for metastatic melanoma. We assessed whether biologic subtype according t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4c40352e051bdc9aefc2783362b190
http://europepmc.org/articles/PMC7831745
http://europepmc.org/articles/PMC7831745
Autor:
Samir Gupta, Subha Madhavan, Ian F. G. King, Shruti Rao, Matthew McCoy, Beth A. Pitel, Ben Ho Park, James L. Chen, Debyani Chakravarty, Peter K. Rogan, Malachi Griffith, Simina M. Boca, Obi L. Griffith, Alex H. Wagner, Jeremy L. Warner
Publikováno v:
Biochemistry Publications
JCO Clinical Cancer Informatics
JCO Clinical Cancer Informatics
PURPOSE The cancer research community is constantly evolving to better understand tumor biology, disease etiology, risk stratification, and pathways to novel treatments. Yet the clinical cancer genomics field has been hindered by redundant efforts to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::344f48e6ed800dc381f71d31f82adda2
https://ir.lib.uwo.ca/context/biochempub/article/1209/viewcontent/cci.19.00169.pdf
https://ir.lib.uwo.ca/context/biochempub/article/1209/viewcontent/cci.19.00169.pdf
1043P NF1 mutations and immune checkpoint inhibitor outcomes in patients with BRAF wildtype melanoma
Autor:
L. Mantle, R. Singh, A. Covelli, T. Pimentel Muniz, Sofia Genta, Diana Paola Arteaga, Alexandra M. Easson, Ian F. G. King, Z. Saeed Kamil, A. Rose, Marcus O. Butler, Anna Spreafico, Samuel Saibil, M. Vilbert, David W. Hogg
Publikováno v:
Annals of Oncology. 32:S874
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cfce072843fcf6fe3b881cdf15a37d8
https://doi.org/10.1016/j.annonc.2021.08.1428
https://doi.org/10.1016/j.annonc.2021.08.1428
Autor:
Deirdre Kelly, Danny Ghazarian, Daniel Vilarim Araujo, John Waldron, Ian F. G. King, D.P. Arteaga Ceballos, Thiago Pimentel Muniz, Z. Saeed Kamil, Marcus O. Butler, Normand Laperriere, David W. Hogg, A. Rose, Samuel Saibil, Hatem Krema, Anna Spreafico
Publikováno v:
Annals of Oncology. 31:S764-S765
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0d33b1ee85313d2a752b874c4fd30a8
https://doi.org/10.1016/j.annonc.2020.08.1267
https://doi.org/10.1016/j.annonc.2020.08.1267
Autor:
Deborah I. Ritter, Rashmi Kanagal-Shamana, Matthew McCoy, Jason D. Merker, Seyed Ali Hosseini, Alex H. Wagner, Shruti Rao, Ian F. G. King, Gordana Raca, Malachi Griffith, Arpad Danos, Angshumoy Roy, Wan-Hsin Lin, Kilannin Krysiak, Jue Wang, Beth A. Pitel, Marilyn M. Li, Shashikant Kulkarni, Jonathan S. Berg, Xinjie Xu, Shamini Selvarajah, Subha Madhavan, Obi L. Griffith, Erica K. Barnell, Funda Meric-Bernstam, Dmitriy Sonkin, Jeremy L. Warner
Publikováno v:
Cancer Genetics. 244:17-18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcbbd81c54ed4959a360eb670cb1bb99
https://doi.org/10.1016/j.cancergen.2020.04.050
https://doi.org/10.1016/j.cancergen.2020.04.050
Autor:
Arpad Danos, Deborah I. Ritter, Dmitriy Sonkin, Xinjie Xu, Shamini Selvarajah, Matthew McCoy, Jue Wang, Gordana Raca, Beth A. Pitel, Marilyn M. Li, Wan-Hsin Lin, Ian F. G. King, Angshumoy Roy, Erica K. Barnell, Kilannin Krysiak, Shashikant Kulkarni, Obi L. Griffith, Jason D. Merker, Rashmi Kanagal-Shamana, Shruti Rao, Jeremy L. Warner, Subha Madhavan, Seyed Ali Hosseini, Alex H. Wagner, Malachi Griffith, Funda Meric-Bernstam
Publikováno v:
Cancer Research. 80:3215-3215
The Clinical Genome (ClinGen) Resource is a US National Human Genome Research Institute (NHGRI)-funded program dedicated to building an expert curated and freely available central resource that defines the clinical relevance of genes and variants for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c9b8f7b6d3554c789f0c2a19b157607
https://doi.org/10.1158/1538-7445.am2020-3215
https://doi.org/10.1158/1538-7445.am2020-3215
Autor:
Karen E. Weck, Margaret W. Leigh, Michael R. Knowles, Dennis J. Campbell, Catherine D. Sanders, Maimoona A. Zariwala, Kay C. Chao, Adam J. Shapiro, Whitney E. Wolf, Ian F. G. King
Publikováno v:
Pediatric pulmonology. 53(11)
Background Primary ciliary dyskinesia (PCD) and cri du chat syndrome (CdCS) are distinct disorders that can co-occur due to a common genetic locus on chromosome 5p. Chronic respiratory symptoms associated with PCD can occur in CdCS and are typically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f37fd1b19e14619e955941941b69407
https://pubmed.ncbi.nlm.nih.gov/30238669
https://pubmed.ncbi.nlm.nih.gov/30238669
Autor:
Ian F. G. King, Michael L. Wallace, Michael S. Sidorov, Benjamin D. Philpot, Mark J. Zylka, Ype Elgersma, Bin Gu, Geeske M. van Woerden, Richard J. Weinberg, Alain C. Burette, Ji Eun E. Han, Matthew C. Judson
Publikováno v:
Neuron, 90(1), 56-69. Cell Press
Loss of maternal UBE3A causes Angelman syndrome (AS), a neurodevelopmental disorder associated with severe epilepsy. We previously implicated GABAergic deficits onto layer (L) 2/3 pyramidal neurons in the pathogenesis of neocortical hyperexcitability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50893469926f75fc6e86c806dc241497
https://pure.eur.nl/en/publications/9fd136b3-7aab-44c5-8c45-bcfb1a3eb8fa
https://pure.eur.nl/en/publications/9fd136b3-7aab-44c5-8c45-bcfb1a3eb8fa
Autor:
Chandri N. Yandava, Terry Magnuson, Joel S. Parker, Stormy J. Chamberlain, Benjamin D. Philpot, Hsien-Sung Huang, J. Mauro Calabrese, Angela M. Mabb, Mark J. Zylka, Jack S. Hsiao, Brandon L. Pearson, Joshua Starmer, Ian F. G. King
Publikováno v:
Nature
Topoisomerases are expressed throughout the developing and adult brain and are mutated in some individuals with autism spectrum disorder (ASD). However, how topoisomerases are mechanistically connected to ASD is unknown. Here we find that topotecan,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b3997b1bcc4e3dea76bd57c1ee34df
http://europepmc.org/articles/PMC3767287
http://europepmc.org/articles/PMC3767287