Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Ian F Hermans"'
Autor:
Ian F Hermans, Christoph H Tripp, Florian Hornsteiner, Zlatko Trajanoski, Patrizia Stoitzner, Marc Schmitz, Natascha Hermann-Kleiter, Francesca Finotello, Janine Vierthaler, Helen Strandt, Antonia Resag, Zhe Fu, Markus Ausserhofer, Sophie Dieckmann, Markus Kanduth, Kathryn Farrand, Sarah Bregar, Niloofar Nemati, Athanasios Seretis, Sudhir Morla, David Mullins, Guido Wollmann, Franca Ronchese
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Tumor-targeted therapy causes impressive tumor regression, but the emergence of resistance limits long-term survival benefits in patients. Little information is available on the role of the myeloid cell network, especially dendritic cells
Externí odkaz:
https://doaj.org/article/8ba13b7814a54dc4b691708cf8293e28
Autor:
Kef K Prasit, Laura Ferrer-Font, Olivia K Burn, Regan J Anderson, Benjamin J Compton, Alfonso J Schmidt, Johannes U Mayer, Chun-Jen J Chen, Nathaniel Dasyam, David S Ritchie, Dale I Godfrey, Stephen R Mattarollo, P Rod Dunbar, Gavin F Painter, Ian F Hermans
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Intratumoural administration of unmethylated cytosine-phosphate-guanine motifs (CpG) to stimulate toll-like receptor (TLR)-9 has been shown to induce tumour regression in preclinical studies and some efficacy in the clinic. Because activated natural
Externí odkaz:
https://doaj.org/article/423fa268183140eca4c64e8a2ff85aed
Autor:
Olivia K Burn, Kathryn Farrand, Tara Pritchard, Sarah Draper, Ching‐wen Tang, Anna H Mooney, Alfonso J Schmidt, Sung H Yang, Geoffrey M Williams, Margaret A Brimble, Matheswaran Kandasamy, Andrew J Marshall, Kate Clarke, Gavin F Painter, Ian F Hermans, Robert Weinkove
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 7, Pp n/a-n/a (2022)
Abstract Objectives Metastasis is the principal cause of breast cancer mortality. Vaccines targeting breast cancer antigens have yet to demonstrate clinical efficacy, and there remains an unmet need for safe and effective treatment to reduce the risk
Externí odkaz:
https://doaj.org/article/3c9b77a20a6e4b3da7b8452985eb9f84
Autor:
Laura Ferrer-Font, Palak Mehta, Phoebe Harmos, Alfonso J Schmidt, Sally Chappell, Kylie M Price, Ian F Hermans, Franca Ronchese, Graham le Gros, Johannes U Mayer
Publikováno v:
eLife, Vol 9 (2020)
Single cell isolation from helminth-infected murine intestines has been notoriously difficult, due to the strong anti-parasite type 2 immune responses that drive mucus production, tissue remodeling and immune cell infiltration. Through the systematic
Externí odkaz:
https://doaj.org/article/24e93b44c4e44e5b843135ff7c8da27d
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140432 (2015)
Ex vivo generated monocyte-derived dendritic cell (moDC)-vaccines have long been touted as promising immunotherapeutic agents for cancer treatment, although the response rate generally remains low. The reasons for this are still unclear and confounde
Externí odkaz:
https://doaj.org/article/78b562a0dba34df492a4689fa781ab17
Autor:
Peter M Ferguson, Kirk W Feindel, Angela Slocombe, Matthew MacKay, Trudy Wignall, Brett Delahunt, Richard D Tilley, Ian F Hermans
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56572 (2013)
Despite advances in non-invasive medical imaging, accurate nodal staging of malignancy continues to rely on surgery. Superparamagnetic iron oxide nanoparticles (IONP) with lymphotropic qualities have shown some promise as contrast agents for MRI of t
Externí odkaz:
https://doaj.org/article/d89d814319124c0a9bb567488486439e
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e65318 (2013)
Cancer immunotherapy with antigen-loaded dendritic cell-based vaccines can induce clinical responses in some patients, but further optimization is required to unlock the full potential of this strategy in the clinic. Optimization is dependent on bein
Externí odkaz:
https://doaj.org/article/1044cd93e6bb43d8a7d4a03ff5bbc83b
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17657 (2011)
Transfer of antigen between antigen-presenting cells (APCs) is potentially a physiologically relevant mechanism to spread antigen to cells with specialized stimulatory functions. Here we show that specific CD8+ T cell responses induced in response to
Externí odkaz:
https://doaj.org/article/7f7de6308c864d4ab0b1161cd7247bc6
Autor:
Clinton P. Turner, Jessica McLay, Ian F. Hermans, Jason Correia, Arnold Bok, Nasim Mehrabi, Stephen Gock, Blake Highet, Maurice A. Curtis, Michael Dragunow
Publikováno v:
Pathology. 54:417-424
Tumour infiltrating lymphocyte (TIL) density is prognostically significant in various tumours, but few studies have investigated its significance in meningioma. This study aimed to investigate how TIL density differs by meningioma histology and wheth
Autor:
Taylor R. Cooney, Kathryn Farrand, Sarah L. Draper, Regan J. Anderson, Phillip M. Rendle, Ian F. Hermans, Benjamin J. Compton, Gavin F. Painter
Publikováno v:
Bioconjugate Chemistry.