Výsledky vyhledávání

Data from Markers of Adenocarcinoma Characteristic of the Site of Origin: Development of a Diagnostic Algorithm

Autor: Karin A. Oien, W. Nicol Keith, Christopher Bellamy, Caroline Verbeke, Jacqueline Mooney, Ian Downie, Alexandra K. Bell, Jan Komorowski, Ernst C. Wit, Torgeir R. Hvidsten, Jayne L. Dennis

Purpose: Patients with metastatic adenocarcinoma of unknown origin are a common clinical problem. Knowledge of the primary site is important for their management, but histologically, such tumors appear similar. Better diagnostic markers are needed to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c64dd357e19c88804d6b69181e4539
https://doi.org/10.1158/1078-0432.c.6518334

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Immunohistochemical Analysis of Peritoneal Mesothelioma and Primary and Secondary Serous Carcinoma of the Peritoneum

Autor: Rodney A. Burnett, Robert J. Barnetson, Christina M. Harper, Ian Downie, Fiona Roberts

Publikováno v: American Journal of Clinical Pathology. 125:67-76

The role of immunohistochemical markers in distinguishing peritoneal mesothelioma from primary or metastatic serous papillary carcinoma of the peritoneum was evaluated. We immunostained 20 peritoneal mesotheliomas (from 14 men and 6 women), 14 primar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f5da7e84e259db8dcb8db5ebee47448
https://doi.org/10.1309/8fchq3vpbwm7b5x9

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Gastrokine 1 is abundantly and specifically expressed in superficial gastric epithelium, down-regulated in gastric carcinoma, and shows high evolutionary conservation

Autor: Steven Bryce, Sharon Burns, Fiona McGregor, W. Nicol Keith, Ian Downie, Karin A. Oien, Rod K Ferrier, Sharlene Butler

Publikováno v: The Journal of Pathology. 203:789-797

Through previous large-scale gene expression profiling we identified a transcript that was abundant in normal stomach and down-regulated in gastric cancer. Genes expressed at similar levels included gastrin, MUC5 and pS2, which are important in gastr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648d3adb68f7e127213b94fe02e0f342
https://doi.org/10.1002/path.1583

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Profiling, comparison and validation of gene expression in gastric carcinoma and normal stomach

Autor: Karin A. Oien, Grant Fullarton, J. Keith Vass, Ian Downie, W. Nicol Keith

Publikováno v: Oncogene. 22:4287-4300

Gastric carcinoma is the fourth most common cause of cancer death worldwide but its molecular biology is poorly understood. We catalogued the genes expressed in two gastric adenocarcinomas and normal stomach, using serial analysis of gene expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5cb316e6701fe94c17206ce69fcb59
https://doi.org/10.1038/sj.onc.1206615

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