Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ian Delahunty"'
Autor:
Hyeong-Min Lee, William C. Wright, Min Pan, Jonathan Low, Duane Currier, Jie Fang, Shivendra Singh, Stephanie Nance, Ian Delahunty, Yuna Kim, Richard H. Chapple, Yinwen Zhang, Xueying Liu, Jacob A. Steele, Jun Qi, Shondra M. Pruett-Miller, John Easton, Taosheng Chen, Jun Yang, Adam D. Durbin, Paul Geeleher
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Combination chemotherapy is crucial for successfully treating cancer. However, the enormous number of possible drug combinations means discovering safe and effective combinations remains a significant challenge. To improve this process, we c
Externí odkaz:
https://doaj.org/article/8ea60511d9b646e7b01a18ad97adfba0
Autor:
Hyeong-Min Lee, William C. Wright, Min Pan, Jonathan Low, Duane Currier, Jie Fang, Shivendra Singh, Stephanie Nance, Ian Delahunty, Yuna Kim, Richard H. Chapple, Yinwen Zhang, Xueying Liu, Jacob A. Steele, Jun Qi, Shondra M. Pruett-Miller, John Easton, Taosheng Chen, Jun Yang, Adam D. Durbin, Paul Geeleher
Combination chemotherapy is crucial for achieving durable cancer cures, however, developing safe and effective drug combinations has been a significant challenge. To improve this process, we conducted large-scale targeted CRISPR knockout screens in d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46d5f67262f1c194f9536abb26a8b55f
https://doi.org/10.1101/2023.04.12.536612
https://doi.org/10.1101/2023.04.12.536612
Autor:
Ian Delahunty, Jianwen Li, Wen Jiang, Chaebin Lee, Xueyuan Yang, Anil Kumar, Zhi Liu, Weizhong Zhang, Jin Xie
Publikováno v:
Small
Therapeutics that can be activated by radiation in situ to enhance the efficacy of radiotherapy are highly desirable. Herein, 7-Dehydrocholesterol (7-DHC), a biosynthetic precursor of cholesterol, as a radiosensitizer, exploiting its ability to propa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f0184328b94720cea087d88dab6869
https://pubmed.ncbi.nlm.nih.gov/35304816
https://pubmed.ncbi.nlm.nih.gov/35304816
Abstract 481: Investigating molecular glues as a new therapeutic approach to high-risk neuroblastoma
Autor:
Ian Delahunty, Gisele Nishiguchi, Yang Zhang, Abigail Fish, Anand Mayasundari, Jun Qi, Brian Abraham, Anang Shelat, Zoran Rankovic, Adam Durbin
Publikováno v:
Cancer Research. 83:481-481
High-risk neuroblastoma (NB) is the most common extracranial solid tumor of childhood. Despite extensive study, treatments remain highly toxic and are often insufficient to cure. Thus, there is an urgent need to develop more effective and less toxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ce382bd0547b605b55c96cf34dc159d
https://doi.org/10.1158/1538-7445.am2023-481
https://doi.org/10.1158/1538-7445.am2023-481