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pro vyhledávání: '"Ian David Starkey"'
Autor:
Shabana Mirza, Mohammad Afshar, Alastair I.H. Murchie, Jonathan Karn, Andrew John Potter, Fareed Aboul-ela, Terry Mark Swarbrick, Catherine Isel, Philippe Vaglio, Martin J. Drysdale, Ian David Starkey, Catherine Denise Prescott, Ben Davis, Justin Bower
Publikováno v:
Journal of Molecular Biology. 336:625-638
The targeting of RNA for the design of novel anti-viral compounds represents an area of vast potential. We have used NMR and computational methods to model the interaction of a series of synthetic inhibitors of the in vitro RNA binding activities of
Autor:
Jonathan Karn, Gabriele Varani, Terry Mark Swarbrick, Ben Davis, Ian David Starkey, Mohammad Afshar, Andrew John Potter, Alastair I.H. Murchie, Martin J. Drysdale, Justin Bower, Georg Lentzen, Fareed Aboul-ela
Publikováno v:
Journal of molecular biology. 336(2)
The targeting of RNA for the design of novel anti-viral compounds has until now proceeded largely without incorporating direct input from structure-based design methodology, partly because of lack of structural data, and complications arising from su