Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Ian D. Spenser"'
Publikováno v:
Canadian Journal of Chemistry. 82:579-582
3-Amino-1-hydroxypropan-2-one (3-amino-1-hydroxyacetone) was prepared in an overall yield of 52% in 6 steps starting with N-phthaloylglycine. This synthesis is readily adaptable for the preparation of bond-labeled samples, i.e., samples that are labe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed23b942a42a284d537507c308834c9e
https://doi.org/10.1139/v04-010
https://doi.org/10.1139/v04-010
Publikováno v:
Canadian Journal of Chemistry. 79:418-425
The mode of incorporation into nicotinamide of label from13C-labeled samples of D-glucose, in Escherichia coli and Saccharomyces cerevisiae, was determined by means of13C NMR spectroscopy. The results, which confirm and extend early studies with radi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5f7f6d01596ca5fbf1cc53fb3de6d1d
https://doi.org/10.1139/v01-056
https://doi.org/10.1139/v01-056
Publikováno v:
Magnetic Resonance in Chemistry. 38:707-718
Several Lythraceae alkaloids containing either a trans-fused (decinine, decodine, decaline) or a cis-fused (decamine, verticillatine, vertaline) quinolizidine ring system were examined by high-field NMR spectroscopy. One- and two-dimensional NMR tech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b09f38dc750643da259b4f3477f0702c
https://doi.org/10.1002/1097-458x(200009)38:9<707::aid-mrc688>3.0.co
https://doi.org/10.1002/1097-458x(200009)38:9<707::aid-mrc688>3.0.co
Publikováno v:
Journal of the American Chemical Society. 120:3581-3589
The mode of incorporation into thiamin of label from [1,2,3,4,5,6-13C6]-d-glucose and other bond-labeled substrates, in a prokaryote, Escherichia coli, and in a eukaryote, Saccharomyces cerevisiae, was determined by means of high field 13C NMR spectr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52a4393425804cf577482c8306b1fcf0
https://doi.org/10.1021/ja973835r
https://doi.org/10.1021/ja973835r
Publikováno v:
Canadian Journal of Chemistry. 75:942-948
New syntheses are described of 5-hydroxypentane-2,3-dione (7) (i.e., laurencione [Formula: see text]) and of 3-amino-1-hydroxypropan-2-one (3-amino-1-hydroxyacetone) (5) hydrochloride, putative precursors of the C5 unit, C-2′,2,3,4,4′, and of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fa8a5fa3fa3ce83d9246693ac56c4b7
https://doi.org/10.1139/v97-113
https://doi.org/10.1139/v97-113
Autor:
Robert L. White, Ian D. Spenser
Publikováno v:
Angewandte Chemie. 109:1096-1111
Die Aufklarung der Biosynthesewege zu Thiamin (Vitamin B1) und dessen Pyrophosphatester, dem wichtigen Coenzym Cocarboxylase, ist und bleibt fur Forscher eine Herausforderung. Die Thiamin-Biosynthese gliedert sich in die voneinander unabhangigen Synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e398eec23287bba8151ead11820b62c
https://doi.org/10.1002/ange.19971091005
https://doi.org/10.1002/ange.19971091005
Autor:
Ian D. Spenser, Robert L. White
Publikováno v:
Angewandte Chemie International Edition in English. 36:1032-1046
The elucidation of the biosynthetic pathway to thiamin (Vitamin B1) and its pyrophosphate ester, the important coenzyme “cocarboxylase”, has challenged researchers for many years and continues to do so. The problem of the origin of thiamin can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c5b9f148bffe444666a11d64468ae03
https://doi.org/10.1002/anie.199710321
https://doi.org/10.1002/anie.199710321
Autor:
Eckardt Wolf, Klaus Himmeldirk, Richard M. Pauloski, Ian D. Spenser, Isaac A. Kennedy, Robert E. Hill, Brian G. Sayer
Publikováno v:
Journal of Biological Chemistry. 271:30426-30435
It is shown by incorporation experiments with 13C bond-labeled substrates, followed by analysis by means of 13C NMR spectroscopy, that two compounds, 1-deoxy-D-xylulose (12) and 4-hydroxy-L-threonine (13), serve as precursors of pyridoxol (vitamin B6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61b763536525713b7ff420caa98bacbc
https://doi.org/10.1074/jbc.271.48.30426
https://doi.org/10.1074/jbc.271.48.30426
Autor:
Eckardt Wolf, Ian D. Spenser
Publikováno v:
The Journal of Organic Chemistry. 60:6937-6940
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8a64e4d54824a5e79b8e2c6e8a8f40f
https://doi.org/10.1021/jo00126a052
https://doi.org/10.1021/jo00126a052
Publikováno v:
Canadian Journal of Chemistry. 73:1329-1337
1-Deoxy-D-xylulose (= 1-deoxy-D-theropentulose) is a precursor of thiamin (Vitamin B1) and of pyridoxine (Vitamin B6) in bacteria. The synthesis of a [2,3-13C2] bond-labeled sample of the compound, to be used for investigations of the biosynthesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::823d9cbe7c72d30f3a4ce158ec0a934a
https://doi.org/10.1139/v95-164
https://doi.org/10.1139/v95-164