Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Ian D. Jenkins"'
Autor:
Ian D. Jenkins, Elizabeth H. Krenske
Publikováno v:
ACS Omega, Vol 5, Iss 13, Pp 7053-7058 (2020)
Externí odkaz:
https://doaj.org/article/5c64eb4ce1d843f992e39e6c9bbf2335
Autor:
Daniel J. G. Johnson, Ian D. Jenkins, Cohan Huxley, Mark J. Coster, Kah Yean Lum, Jonathan M. White, Vicky M. Avery, Rohan A. Davis
Publikováno v:
Molecules, Vol 26, Iss 9, p 2421 (2021)
A radical approach to late-stage functionalization using photoredox and Diversinate™ chemistry on the Open Source Malaria (OSM) triazolopyrazine scaffold (Series 4) resulted in the synthesis of 12 new analogues, which were characterized by NMR, UV,
Externí odkaz:
https://doaj.org/article/6f3deda7a0494610ab87f1141ddbc384
Autor:
Jianying Han, Miaomiao Liu, Ian D. Jenkins, Xueting Liu, Lixin Zhang, Ronald J. Quinn, Yunjiang Feng
Publikováno v:
Marine Drugs, Vol 18, Iss 7, p 352 (2020)
The marine-derived fungus Aspergillus fumigatus MF071, isolated from sediment collected from the Bohai Sea, China, yielded two new compounds 19S,20-epoxy-18-oxotryprostatin A (1) and 20-hydroxy-18-oxotryprostatin A (2), in addition to 28 known compou
Externí odkaz:
https://doaj.org/article/f629e2bf1bec46839b8b697aeaae6218
Publikováno v:
Molecules, Vol 24, Iss 21, p 3938 (2019)
The reaction of papaverine with a series of Baran DiversinatesTM is reported. Although the yields were low, it was possible to synthesize a small biodiscovery library using this plant alkaloid as a scaffold for late-stage C−H functionalization. Ten
Externí odkaz:
https://doaj.org/article/2e5345c6703f47fd8f6bda7c3aaaf6a4
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 5, Pp o1468-o1469 (2012)
The racemic title compound, C9H11NO4·H2O, a tricyclic rearranged aminonorbornane dicarboxylic acid, is a conformationally rigid analogue of glutamic acid and exists as an ammonium-carboxylate zwitterion, with the bridghead carboxylic acid group anti
Externí odkaz:
https://doaj.org/article/33dba9fb911048b8b5a6c0fbd579fa3f
Publikováno v:
Acta Crystallographica Section E, Vol 64, Iss 12, Pp o2492-o2493 (2008)
The title compound, C13H18N2O4, crystallizes as discrete molecules associated as N—H...O hydrogen-bonded dimers disposed about a crystallographic inversion centre. The structure is the first solid-state structure for a 3-acetylpyridone without C-4
Externí odkaz:
https://doaj.org/article/2c3c9cfa7882491982644ffdd16888e0
Publikováno v:
Acta Crystallographica Section E, Vol 64, Iss 9, Pp o1738-o1738 (2008)
The crystal structure of the title compound, C27H45N3, has been determined as part of our investigation into the hydrophobic modification of aminoglycoside antibiotics. The isopropyl group showed disorder for the tertiary carbon (equal occupancies),
Externí odkaz:
https://doaj.org/article/80f13bf982594241a89bf180b1bbac58
Autor:
Elizabeth H. Krenske, Ian D. Jenkins
Publikováno v:
ACS Omega
ACS Omega, Vol 5, Iss 13, Pp 7053-7058 (2020)
ACS Omega, Vol 5, Iss 13, Pp 7053-7058 (2020)
The hydrosilane/potassium tert-butoxide reagent system has attracted significant attention over the last 5 years since the discovery of its ability to silylate heteroarene C-H bonds. Numerous useful HSiR3/KO t Bu-mediated transformations are now know
Publikováno v:
Tetrahedron. 120:132877
Autor:
Ian D. Jenkins, Rebecca H. Pouwer, Ronald J. Quinn, Mariyam Murtaza, Fatemeh Mazraati Tajabadi, Miaomiao Liu, Yousef Dashti, Marc Ronald Campitelli, Stephen A. Wood, George D. Mellick
Publikováno v:
Journal of medicinal chemistry. 61(15)
A chemoinformatic method was developed to extract nonflat scaffolds embedded in natural products within the Dictionary of Natural Products (DNP). The cedrane scaffold was then chosen as an example of a nonflat scaffold that directs substituents in th