Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Ian D. Chin"'
Autor:
Daniel C. Quesnelle, Cindy Huang, Jeffrey R. Boudreau, Annie Lam, Jadine Paw, William G. Bendena, Ian D. Chin-Sang
Publikováno v:
Developmental Biology. 497:33-41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e749660a1a3e7c82d7da25e1975435fe
https://doi.org/10.1016/j.ydbio.2023.02.010
https://doi.org/10.1016/j.ydbio.2023.02.010
Publikováno v:
microPublication biology. 2022
Phosphatase and Tensin Homolog (PTEN) acts as a key suppressor of the insulin signaling pathway and thus regulates cell growth and development (Leslie et al., 2008). In humans, this protein still has numerous clinically important variants of unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd62a3b94c254341f53622e74881e4ac
https://pubmed.ncbi.nlm.nih.gov/36530472
https://pubmed.ncbi.nlm.nih.gov/36530472
Publikováno v:
International Journal of Molecular Sciences. 24:6963
MicroRNAs are critical regulators of post-transcriptional gene expression in a wide range of taxa, including invertebrates, mammals, and plants. Since their discovery in the nematode, Caenorhabditis elegans, miRNA research has exploded, and they are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49f7015e885fe0a4183904cf61f03a13
https://doi.org/10.3390/ijms24086963
https://doi.org/10.3390/ijms24086963
Publikováno v:
PLoS Genetics, Vol 12, Iss 5, p e1006050 (2016)
C. elegans inhabit environments that require detection of diverse stimuli to modulate locomotion in order to avoid unfavourable conditions. In a mammalian context, a failure to appropriately integrate environmental signals can lead to Parkinson's, Al
Externí odkaz:
https://doaj.org/article/0a194b6313394ae3b13a15ad4bd1e941
Autor:
Ian D. Chin-Sang, William G. Bendena
Publikováno v:
Advances in Invertebrate (Neuro)Endocrinology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d63e8608a587f8ae0669fb2b5796363
https://doi.org/10.1201/9781003029854-3
https://doi.org/10.1201/9781003029854-3
Publikováno v:
General and comparative endocrinology. 295
The sesquiterpenoid juvenile hormone(s) (JHs) of insects are the primary regulators of growth, metamorphosis, and reproduction in most insect species. As a consequence, it is essential that JH production be precisely regulated so that it is present o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce01fabb3692d4635e75a64ad74e7e8
https://pubmed.ncbi.nlm.nih.gov/32413346
https://pubmed.ncbi.nlm.nih.gov/32413346
Publikováno v:
PLoS Genetics, Vol 8, Iss 2, p e1002513 (2012)
The Eph receptor tyrosine kinases (RTKs) are regulators of cell migration and axon guidance. However, our understanding of the molecular mechanisms by which Eph RTKs regulate these processes is still incomplete. To understand how Eph receptors regula
Externí odkaz:
https://doaj.org/article/f103616358b84db29bb96e8423ab16a8
Publikováno v:
Peptides. 145:170640
The insulin/insulin-like growth factor signaling pathway is an evolutionary conserved pathway across metazoans and is required for development, metabolism and behavior. This pathway is associated with various human metabolic disorders and cancers. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba47fa44e150518d468c7d3f0629377
https://doi.org/10.1016/j.peptides.2021.170640
https://doi.org/10.1016/j.peptides.2021.170640
Publikováno v:
Development. 145
Caenorhabditis elegans that hatch in the absence of food stop their postembryonic development in a process called L1 arrest. Intriguingly, we find that the postembryonic Q neuroblasts divide and migrate during L1 arrest in mutants that have lost the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c6d0022b3a396edbbd8809a659e8fec
https://doi.org/10.1242/dev.166876
https://doi.org/10.1242/dev.166876
Autor:
Tony Papanicolaou, William G. Bendena, Ian D. Chin-Sang, Shanqing Zheng, Hilton Chiu, Jeffrey R. Boudreau
The human genome encodes 10 insulin-like genes, whereas the Caenorhabditis elegans genome remarkably encodes 40 insulin-like genes. Knockout strategies to determine the roles of all the insulin/insulin-like peptide ligands (INS) in C. elegans has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ab338b797dd4f79e7ffd915728c5cb
https://europepmc.org/articles/PMC6204898/
https://europepmc.org/articles/PMC6204898/