Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Ian D Tomlinson"'
Autor:
Ian D. Tomlinson, Oleg Kovtun, Ruben Torres, Laurel G. Bellocchio, Travis Josephs, Sandra J. Rosenthal
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
The serotonin transporter (SERT) is the primary target for selective serotonin reuptake inhibitor (SSRI) antidepressants that are thought to exert their therapeutic effects by increasing the synaptic concentration of serotonin. Consequently, probes t
Externí odkaz:
https://doaj.org/article/32437af905a24b7bb07c718772412d08
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225339 (2019)
The presynaptic dopamine transporter mediates rapid reuptake of synaptic dopamine. Although cell surface DAT trafficking recently emerged as an important component of DAT regulation, it has not been systematically investigated. Here, we apply our sin
Externí odkaz:
https://doaj.org/article/d46b5ee14c7e450c87c09ac87571de2e
Publikováno v:
Polymer. 265:125582
Publikováno v:
Molecules, Vol 7, Iss 11, Pp 777-790 (2002)
The synthesis of 6-(2,5-dimethoxy-4-(2-aminopropyl)phenyl)hexylthiol, an agonist with a very high affinity for the 5HT2A serotonin receptor subtype is reported. This agonist was designed to be attached to highly fluorescent cadmium selenide/zinc sulf
Externí odkaz:
https://doaj.org/article/c5daaaa4e0c84610b7a4d5912870011d
Autor:
Ian D. Tomlinson, Jody C. May, Rachel A. Harris, Kevin M. Buck, Sandra J. Rosenthal, John A. McLean, David M. Hercules
Publikováno v:
Polymer. 254:125069
Autor:
Jody C. May, Ian D. Tomlinson, Berkley M. Ellis, David M. Hercules, John A. McLean, Rachel A. Harris, Jaqueline A. Picache, Emanuel Zlibut
Publikováno v:
Rapid Communications in Mass Spectrometry. 34
RATIONALE Commercial-grade polymer synthesis is performed via melt polymerization, which leads to polydispersion. The work reported herein provides a synthetic strategy to produce mono-dispersive polyurethane oligomers and an analytical strategy to d
Autor:
Lucas B. Thal, James R. McBride, Victor R. Mann, Douglas G. McMahon, Bruce E. Cohen, Sandra J. Rosenthal, Kemar R. Reid, Ian D. Tomlinson, David Sprinzen
Publikováno v:
Biomaterials science, vol 8, iss 3
Semiconductor quantum dots (QDs) have demonstrated utility in long-term single particle tracking of membrane proteins in live cells in culture. To extend the superior optical properties of QDs to more physiologically relevant cell platforms, such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d626eaf1e1327a97af406d676f317440
https://europepmc.org/articles/PMC7002256/
https://europepmc.org/articles/PMC7002256/
Autor:
Riley S. Ferguson, Emily J. Ross, Danielle M. Bailey, Ian D. Tomlinson, Oleg Kovtun, Michael P. Frankland, Jonathan Greer, Sandra J. Rosenthal, Lucas B. Thal, Zachary A. Glaser, Lauren Harris
Publikováno v:
Chemical Physics Letters. 706:741-752
The use of nanometer-sized semiconductor crystals, known as quantum dots, allows us to directly observe individual biomolecular transactions through a fluorescence microscope. Here, we review the evolution of single quantum dot tracking over the past
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225339 (2019)
PLoS ONE
PLoS ONE
The presynaptic dopamine transporter mediates rapid reuptake of synaptic dopamine. Although cell surface DAT trafficking recently emerged as an important component of DAT regulation, it has not been systematically investigated. Here, we apply our sin
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(8)
We have synthesized 3 analogs of the dopamine D2 receptor (D2 DR) antagonist spiperone that can be conjugated to streptavidin-coated quantum dots via a pegylated biotin derivative. Using fluorescent imaging we demonstrate that substitution on the spi