Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Ian D, Kerr"'
Autor:
Akhil Jain, Philippa Wade, Snow Stolnik, Alistair N. Hume, Ian D. Kerr, Beth Coyle, Frankie Rawson
Publikováno v:
ACS Omega, Vol 9, Iss 42, Pp 42923-42931 (2024)
Externí odkaz:
https://doaj.org/article/a3db7f1e7ffe4d6ea888a32056ba0014
Autor:
Franziska Linke, James E. C. Johnson, Stefanie Kern, Christopher D. Bennett, Anbarasu Lourdusamy, Daniel Lea, Steven C. Clifford, Catherine L. R. Merry, Snow Stolnik, Morgan R. Alexander, Andrew C. Peet, David J. Scurr, Rian L. Griffiths, Anna M. Grabowska, Ian D. Kerr, Beth Coyle
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-18 (2023)
Abstract The most common malignant brain tumour in children, medulloblastoma (MB), is subdivided into four clinically relevant molecular subgroups, although targeted therapy options informed by understanding of different cellular features are lacking
Externí odkaz:
https://doaj.org/article/8e0594bb9b0f4ee79da8bd0f140e5dd2
Autor:
Durgagauri H. Sabnis, Lisa C. D. Storer, Jo-Fen Liu, Hannah K. Jackson, J. P. Kilday, Richard G. Grundy, Ian D. Kerr, Beth Coyle
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Abstract Three of the hallmarks of poor prognosis in paediatric ependymoma are drug resistance, local invasion and recurrence. We hypothesised that these hallmarks were due to the presence of a sub-population of cancer stem cells expressing the multi
Externí odkaz:
https://doaj.org/article/502c6a04b51647b3a5dd47133c1f5c73
Autor:
Hannah K. Jackson, Christine Mitoko, Franziska Linke, Donald Macarthur, Ian D. Kerr, Beth Coyle
Publikováno v:
Cancers, 15(9):2601. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers; Volume 15; Issue 9; Pages: 2601
Cancers; Volume 15; Issue 9; Pages: 2601
Extracellular vesicles (EVs) have emerged as pivotal mediators of communication in the tumour microenvironment. More specifically, nanosized extracellular vesicles termed exosomes have been shown to contribute to the establishment of a premetastatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6f47fe1602d637ef93e22bf224bec5
https://doi.org/10.3390/cancers15092601
https://doi.org/10.3390/cancers15092601
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 3012 (2021)
The five members of the mammalian G subfamily of ATP-binding cassette transporters differ greatly in their substrate specificity. Four members of the subfamily are important in lipid transport and the wide substrate specificity of one of the members,
Externí odkaz:
https://doaj.org/article/689eec9b01914b47a7a84cd5566a3b82
Autor:
Louisa Taylor, Philippa K. Wade, James E. C. Johnson, Macha Aldighieri, Sonia Morlando, Gianpiero Di Leva, Ian D. Kerr, Beth Coyle
Publikováno v:
Cancers
Volume 15
Issue 4
Pages: 1086
Volume 15
Issue 4
Pages: 1086
Therapy resistance represents an unmet challenge in the treatment of medulloblastoma. Accordingly, the identification of targets that mark drug-resistant cell populations, or drive the proliferation of resistant cells, may improve treatment strategie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab8720b7437a4e95e555b223672ae66
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 759 (2020)
ABCG2 is one of a triumvirate of human multidrug ATP binding cassette (ABC) transporters that are implicated in the defense of cells and tissues against cytotoxic chemicals, but these transporters can also confer chemotherapy resistance states in onc
Externí odkaz:
https://doaj.org/article/215ca39c25854b2f806aac93da241091
Autor:
Luke, Broadbent, Peer, Depping, Alexis, Lodé, Afroditi, Vaitsopoulou, David, Hardy, Hoor, Ayub, James, Mitchell-White, Ian D, Kerr, Alan D, Goddard, Roslyn M, Bill, Alice J, Rothnie
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2507
One of the big challenges for the study of structure and function of membrane proteins is the need to extract them from the membrane. Traditionally this was achieved using detergents which disrupt the membrane and form a micelle around the protein, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e0530297b7f189170642b14dec4ba9e
https://pubmed.ncbi.nlm.nih.gov/35773594
https://pubmed.ncbi.nlm.nih.gov/35773594
Autor:
Kevin Beaver, Samantha Louise Boeshore, Wanqi Liang, Jan Šimura, G. Eric Schaller, Charlie Hodgens, Karin Ljung, Joseph J. Kieber, Kartika Sari, Ian D. Kerr, Emily J. Tallerday, Dawei Xu, Christian A. Burr, Allison Melling, Rahul Bhosale, John Vaughan-Hirsch, Anthony Bishopp
Publikováno v:
The Plant Journal. 106:159-173
The phytohormone cytokinin plays a significant role in nearly all aspects of plant growth and development. Cytokinin signaling has primarily been studied in the dicot model Arabidopsis, with relatively little work done in monocots, which include rice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a9f9ec44bc07ec7e3700d66f53b369
https://doi.org/10.1111/tpj.15156
https://doi.org/10.1111/tpj.15156
Autor:
Anbarasu Lourdusamy, Ian D. Kerr, Macha Aldighieri, Franziska Linke, Beth Coyle, Catherine L.R. Merry, Anna M. Grabowska, Snow Stolnik
Publikováno v:
The Journal of Pathology
© 2020 The Authors. The Journal of Pathology published by John Wiley & Sons, Ltd. on behalf of The Pathological Society of Great Britain and Ireland. Medulloblastoma (MB) is the most common malignant brain tumour in children and is subdivided into f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c638dfd313858ca40975892a6895c9
https://doi.org/10.1002/path.5591
https://doi.org/10.1002/path.5591