Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Ian D, Forsythe"'
Autor:
Amy Richardson, Victoria Ciampani, Mihai Stancu, Kseniia Bondarenko, Sherylanne Newton, Joern R Steinert, Nadia Pilati, Bruce P Graham, Conny Kopp-Scheinpflug, Ian D Forsythe
Publikováno v:
eLife, Vol 11 (2022)
Kv3 potassium currents mediate rapid repolarisation of action potentials (APs), supporting fast spikes and high repetition rates. Of the four Kv3 gene family members, Kv3.1 and Kv3.3 are highly expressed in the auditory brainstem and we exploited thi
Externí odkaz:
https://doaj.org/article/7a5ebf62e769488487d88c858f972480
Publikováno v:
Frontiers in Neural Circuits, Vol 15 (2021)
Nitric oxide (NO) is of fundamental importance in regulating immune, cardiovascular, reproductive, neuromuscular, and nervous system function. It is rapidly synthesized and cannot be confined, it is highly reactive, so its lifetime is measured in sec
Externí odkaz:
https://doaj.org/article/44de22f0a07d40abaf3f99a568fce089
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201022 (2018)
Hyperbilirubinemia (jaundice) is caused by raised levels of unconjugated bilirubin in the blood. When severe, susceptible brain regions including the cerebellum and auditory brainstem are damaged causing neurological sequelae such as ataxia, hearing
Externí odkaz:
https://doaj.org/article/01f93a05337c4559b2141620377520d6
Autor:
Victoria Ciampani, Nasreen Choudhury, Michelle Anderson, Ian D. Forsythe, Sophie M. Walter, Conny Kopp-Scheinpflug, Susan W. Robinson, Deborah M. Linley, Joern R. Steinert, Vincenzo Marra, Amy Richardson
Publikováno v:
The Journal of Physiology. 598:2199-2222
Kv3.1 and Kv3.3 subunits are highly expressed in the auditory brainstem, with little or no mRNA for Kv3.2 or Kv3.4. Changes in Kv3 currents and action potential (AP) firing were analysed from wild-type, Kv3.1 and Kv3.3 knockout (KO) mice. Both Kv3.1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb33bff9fa052d9af775b565ded1e80
https://doi.org/10.1113/jp279668
https://doi.org/10.1113/jp279668
Autor:
Amy Richardson, Victoria Ciampani, Mihai Stancu, Kseniia Bondarenko, Sherylanne Newton, Joern R Steinert, Nadia Pilati, Bruce P Graham, Conny Kopp-Scheinpflug, Ian D Forsythe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b300739b5db31eee6ad171f121d9e8c5
https://doi.org/10.7554/elife.75219.sa2
https://doi.org/10.7554/elife.75219.sa2
Autor:
Mihai Stancu, Nadia Pilati, Bruce P. Graham, Ian D. Forsythe, Joern R. Steinert, Conny Kopp-Scheinpflug, Amy Richardson, Sherylanne Newton, Victoria Ciampani
SummaryKv3 potassium currents mediate rapid repolarization of action potentials (AP), supporting fast spikes and high repetition rates. Of the four Kv3 gene family members, Kv3.1 and Kv3.3 are highly expressed in the auditory brainstem and we exploit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fd16f6335cd8cd6cbebe4343b09fa03
https://doi.org/10.1101/2021.11.02.466934
https://doi.org/10.1101/2021.11.02.466934
Publikováno v:
Frontiers in Neural Circuits
Frontiers in Neural Circuits, Vol 15 (2021)
Frontiers in Neural Circuits, Vol 15 (2021)
Nitric oxide (NO) is of fundamental importance in regulating immune, cardiovascular, reproductive, neuromuscular, and nervous system function. It is rapidly synthesized and cannot be confined, it is highly reactive, so its lifetime is measured in sec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63917b6f468771db3ba4dc83d1ac660d
https://doi.org/10.3389/fncir.2021.759342
https://doi.org/10.3389/fncir.2021.759342
Publikováno v:
Frontiers in Neural Circuits, Vol 9 (2015)
Externí odkaz:
https://doaj.org/article/c8871f587e51418c99aa3729a02f489a
Autor:
Lina eYassin, Susanne eRadtke-Schuller, Hila eAsraf, Benedikt eGrothe, Michal eHershfinkel, Ian D Forsythe, Conny eKopp-Scheinpflug
Publikováno v:
Frontiers in Neural Circuits, Vol 8 (2014)
Glycinergic inhibition plays a central role in the auditory brainstem circuitries involved in sound localization and in the encoding of temporal action potential firing patterns. Modulation of this inhibition has the potential to fine-tune informatio
Externí odkaz:
https://doaj.org/article/dbbed40d41044e63bb75f10b206d335c
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32256 (2012)
Nitric Oxide (NO) is a diffusible second messenger that modulates ion channels, intrinsic excitability and mediates synaptic plasticity. In light of its activity-dependent generation in the principal neurons of the medial nucleus of the trapezoid bod
Externí odkaz:
https://doaj.org/article/b2f75fb25b7e40d38aa6cd53dcd26366