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pro vyhledávání: '"Ian C. Sutton"'
Autor:
Charlotte Degorre, Ian C. Sutton, Stacey L. Lehman, Uma T. Shankavaram, Kevin Camphausen, Philip J. Tofilon
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background The invasive nature of GBM combined with the diversity of brain microenvironments creates the potential for a topographic heterogeneity in GBM radioresponse. Investigating the mechanisms responsible for a microenvironment-induced
Externí odkaz:
https://doaj.org/article/acc01da916514c0a8e8f39bc81e249be
Publikováno v:
Cancer Research. 83:2413-2413
Glioblastomas (GBM) have long been classified as radioresistant tumors. Glioblastoma stem-like cells (GSCs) are a portion of GBM’s heterogenous cell population and are generally considered to be crucial drivers of tumorigenesis and radioresistance.
Autor:
Charlotte M. Degorre, Ian C. Sutton, Stacey L. Lehman, Uma T. Shankavaram, Kevin A. Camphausen, Philip J. Tofilon
Publikováno v:
Cancer Research. 82:6057-6057
We have previously reported (Int J Radiat Oncol Biol Phys. 107(1):194-201, 2020) that human GBM-stem like cells (GSCs) implanted into the right striatum of nude mice migrate/invade throughout the right hemisphere (RH) as well as into the olfactory bu