Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ian C. Dewhurst"'
Autor:
EFSA Panel on Genetically Modified Organisms (GMO), Hanspeter Naegeli, Jean‐Louis Bresson, Tamas Dalmay, Ian C Dewhurst, Michelle M Epstein, Philippe Guerche, Jan Hejatko, Francisco J Moreno, Ewen Mullins, Fabien Nogué, Nils Rostoks, Jose J Sánchez Serrano, Giovanni Savoini, Eve Veromann, Fabio Veronesi, Michael B Bonsall, John Mumford, Ernst A Wimmer, Yann Devos, Konstantinos Paraskevopoulos, Leslie G Firbank
Publikováno v:
EFSA Journal, Vol 18, Iss 11, Pp n/a-n/a (2020)
Abstract Advances in molecular and synthetic biology are enabling the engineering of gene drives in insects for disease vector/pest control. Engineered gene drives (that bias their own inheritance) can be designed either to suppress interbreeding tar
Externí odkaz:
https://doaj.org/article/4999a56276f5462ea7816c4cf0802204
Autor:
Ian C. Dewhurst
Publikováno v:
Regulatory Toxicology in the European Union ISBN: 9781782620662
This chapter presents information on the history, legislation and current approaches to assessing and controlling the potential hazards and risk of exposure to chemicals in the workplace. Historically, investigations of workplace exposures were post
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7868bb1de9c051f0408437d12457bc1
https://doi.org/10.1039/9781782622222-00557
https://doi.org/10.1039/9781782622222-00557
Autor:
Ian Indans, Michael R. Woolhiser, Ian C. Dewhurst, Jon A. Hotchkiss, Lesley Earl, Robert Guest, Richard Billington, Sean C. Gehen, Stuart Creton
Publikováno v:
Critical Reviews in Toxicology. 40:50-83
Assessment of the acute systemic oral, dermal, and inhalation toxicities, skin and eye irritancy, and skin sensitisation potential of chemicals is required under regulatory schemes worldwide. In vivo studies conducted to assess these endpoints can so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4beb8615b047f965dcd379b42e2a9df7
https://doi.org/10.3109/10408440903401511
https://doi.org/10.3109/10408440903401511
Autor:
Ian C. Dewhurst
Publikováno v:
Food Additives and Contaminants. 17:611-615
To perform risk assessments for short term dietary intakes of pesticides it is necessary to determine an acceptable level of exposure from the available toxicity studies. This type of assessment is a relatively new development in regulatory toxicolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b99ed0623fe2f0c826c2f12928e59888
https://doi.org/10.1080/026520300412528
https://doi.org/10.1080/026520300412528
Autor:
Alan R. Boobis, Nancy G. Doerrer, Douglas C. Wolf, Samuel M. Cohen, John E. Doe, Jennifer Y. Tanir, Ronald N. Hines, J. Craig Rowlands, Richard D. Phillips, Michael Dellarco, Ammie N. Bachman, Michelle R. Embry, Angelo Moretto, Ian C. Dewhurst, David R. Bell, Timothy P. Pastoor
The Health and Environmental Sciences Institute (HESI)-coordinated Risk Assessment in the 21st Century (RISK21) project was initiated to develop a scientific, transparent, and efficient approach to the evolving world of human health risk assessment,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38bebb419b8626edb345deeb40e2eecf
http://hdl.handle.net/11577/3381403
http://hdl.handle.net/11577/3381403
Autor:
Alan R. Boobis, Nancy G. Doerrer, Richard D. Phillips, Douglas C. Wolf, John E. Doe, Michael Dellarco, Timothy P. Pastoor, Jennifer Y. Tanir, Ronald N. Hines, David R. Bell, J. Craig Rowlands, Ammie N. Bachman, Samuel M. Cohen, Michelle R. Embry, Angelo Moretto, Ian C. Dewhurst
The RISK21 integrated evaluation strategy is a problem formulation-based exposure-driven risk assessment roadmap that takes advantage of existing information to graphically represent the intersection of exposure and toxicity data on a highly visual m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::740aa2d16d75b3e4083c833e5ce76cdf
http://hdl.handle.net/11577/3381435
http://hdl.handle.net/11577/3381435
Autor:
Ian C Dewhurst
Publikováno v:
Mammalian Toxicology of Insecticides ISBN: 9781849731911
This chapter focuses primarily on insecticides based on viable microorganisms. Other biological insecticides such as plant extracts (e.g. nicotine, azadirachtin) and purified fermentation products (e.g. avermectins and spinosins) are covered in other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f7f26f4863a85004d0d892085ee5c11
https://doi.org/10.1039/9781849733007-00302
https://doi.org/10.1039/9781849733007-00302
Autor:
Christian Strupp, Tina Mehta, Bennard van Raavenzway, Richard Lewis, Richard Billington, Ian C. Dewhurst
Publikováno v:
Toxicology Letters. 211:S176
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46c12a360fee3989b400ec3bf3b817fe
https://doi.org/10.1016/j.toxlet.2012.03.636
https://doi.org/10.1016/j.toxlet.2012.03.636
Autor:
Cora O'Neill, Clement E. Ekuwem, David Williams, Crawford D. Sinclair, Roger Griffiths, Ian C. Dewhurst
Publikováno v:
European Journal of Biochemistry. 137:467-478
L-Homocysteine and pyridoxal 5'-phosphate (PxyP) inhibited [3H]muscimol binding to freeze-thawed, Triton-treated calf brain membranes (containing high-affinity muscimol-binding sites: Kd 9.5 +/- 0.6 nM, Bmax 5.2 +/- 0.2 pmol/mg protein). The homocyst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f772dbeef4d76fecf80c03921ca2455
https://doi.org/10.1111/j.1432-1033.1983.tb07850.x
https://doi.org/10.1111/j.1432-1033.1983.tb07850.x