Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Ian C. Gray"'
Autor:
Andreas Rechtsteiner, Luis M. Rocha
Publikováno v:
Clinical Chemistry. 50:2471-2472
This book addresses a curious need for greater interaction between genetics and bioinformatics. One would expect the two disciplines to interact profusely, given, as the authors put it, their “strong common grounding in statistical methodology, dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::807a89d00cda56f6b602bfa0cf3d34a0
https://doi.org/10.1373/clinchem.2003.020909
https://doi.org/10.1373/clinchem.2003.020909
Chromosome band 10q24 is rich in genes involved in development, tumorigenesis, neurological disorders, hormone metabolism, and environmentally induced disease susceptibility. We have constructed an STS-based integrated physical and genetic map of 10q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8269dea017c47de4cc721a0ad7598e
https://ora.ox.ac.uk/objects/uuid:2ca77d35-559a-463d-94d6-2752cf4069ec
https://ora.ox.ac.uk/objects/uuid:2ca77d35-559a-463d-94d6-2752cf4069ec
Autor:
David John Miller, John S. Mills, Diana Kuehn, Matthias W. Büttner, Bin Zhu, L. H. Tam, Philip Avlar BioVentures Mitchell, David Tebbe, Christian Burschka, Helen Rapley, Ian C. Gray, Parameswary A. Muniandy, Reinhold Tacke, Matthew J. Barnes, Jürgen O. Daiss, Alan G. Hendrick, Julie B. H. Warneck, Richard Conroy, Graham A. Showell, John Gary Montana
Publikováno v:
ChemMedChem. 6:2070-2080
AG-045572 (CMPD1, 1 a) is a nonpeptidic gonadotropin-releasing hormone (GnRH) antagonist that has been investigated for the treatment of sex hormone-related diseases. In the context of systematic studies on sila-substituted drugs, the silicon analogu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f0906f5604ca83099549d80545ab529
https://doi.org/10.1002/cmdc.201100318
https://doi.org/10.1002/cmdc.201100318
Autor:
Ian C. Gray, Michael R. Barnes
Publikováno v:
Bioinformatics for Geneticists
List of Contributors. Foreword. SECTION I: AN INTRODUCTION TO BIOINFORMATICS FOR THE GENETICIST. Introduction: The Role of Genetic Bioinformatics (Michael R. Barnes and Ian C. Gray). Internet Resources for the Geneticist (Michael R. Barnes and Christ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52a3279a20563cb3a186fc93a5aa9702
https://doi.org/10.1002/9780470059180
https://doi.org/10.1002/9780470059180
Publikováno v:
Comparative and Functional Genomics, Vol 6, Iss 5-6, Pp 268-276 (2006)
Comparative and Functional Genomics
Comparative and Functional Genomics, Vol 6, Iss 5-6, Pp 268-276 (2005)
Comparative and Functional Genomics
Comparative and Functional Genomics, Vol 6, Iss 5-6, Pp 268-276 (2005)
The aryl hydrocarbon receptor nuclear translocator (ARNT) and cathepsin K (CTSK) genes lie in a tandem head-to-tail arrangement on human chromosome 1. The two genes are in extremely close proximity; the usualCTSKtranscription start site is less than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75926fd509828a0dd373b65fbbf9ce10
https://doaj.org/article/b550f21e481d4750ac3c1a222dd74072
https://doaj.org/article/b550f21e481d4750ac3c1a222dd74072
Autor:
David Edwards, Lucie Vizor, Shelly Fuller, Emma Horner, Saffron Brady, Nicholas J. Parkinson, David I. Campbell, Emma L. Coghill, Richard McKeone, Zuzanna Lalanne, Steve D.M. Brown, Roger D. Cox, Pete Glenister, Ann F. C. Roberts, Susan Rodger, David A. Keays, Andy Greenfield, Nigel K. Spurr, Jessica Weedon, Alison Hugill, Mohamed M. Quwailid, Sara Wells, Ian C. Gray, Paul Woodman, Samuel G. Cox, John Willan, Jackie Hunter, Hamish McMath, Neil Dear, Joanne Carey
Publikováno v:
Mammalian Genome. 15:585-591
N-ethyl-N-nitrosourea (ENU) introduces mutations throughout the mouse genome at relatively high efficiency. Successful high-throughput phenotype screens have been reported and alternative screens using sequence-based approaches have been proposed. Fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b742dee89b0077868053fb0b867080
https://doi.org/10.1007/s00335-004-2379-z
https://doi.org/10.1007/s00335-004-2379-z
Autor:
Lesley J. Rooke, John A. Curtin, Nigel K. Spurr, Ian C. Gray, Jo Peters, Ian D. Latham, JE Martin, Elizabeth M. C. Fisher, Lucie Vizor, Sohaila Rastan, Steve D.M. Brown, Derek C. Rogers, Vicky Tsipouri, A. Jackie Hunter, Claire A. Parsons, Colin M. Clapham, P Nolan
Publikováno v:
Comparative and Functional Genomics, Vol 5, Iss 2, Pp 123-127 (2004)
Comparative and Functional Genomics
Comparative and Functional Genomics
Three mutant mice with pigmentation phenotypes were recovered from a genomewide random mouse chemical mutagenesis study. White toes (Whto; MGI:1861986), Belly spot and white toes (Bswt; MGI:2152776) and Dark footpads 2 (Dfp2; MGI:1861991) were identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4855d7b9e8a215f46544578225b122d
https://doaj.org/article/3cb652a5fa51480fb8aa6345a8775d99
https://doaj.org/article/3cb652a5fa51480fb8aa6345a8775d99
Autor:
Ruth M. Arkell, Patrick M. Nolan, Andrew J. Copp, Philip Stanier, Steve D.M. Brown, Ian C. Gray, Karen P. Steel, Deborah J. Henderson, Jennifer N. Murdoch, Nigel K. Spurr, Bruce Cattanach, Vicky Tsipouri, Elizabeth M. C. Fisher, Elizabeth Quint, John A. Curtin
Publikováno v:
Current Biology. 13(13):1129-1133
We identified two novel mouse mutants with abnormal head-shaking behavior and neural tube defects during the course of independent ENU mutagenesis experiments. The heterozygous and homozygous mutants exhibit defects in the orientation of sensory hair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad768889430a65c3e4481ea049aa2443
Autor:
Ian C. Gray, Nigel K. Spurr, A J Hunter, Patrick M. Nolan, Brown Sdm., E L Jones, Alexander Jeans, Anna Katharina Simon, Peter L. Oliver, Pete Glenister, Adrian M. Isaacs, Kay E. Davies, A Potter, B H Hovik, Lucie Vizor
Publikováno v:
The Journal of Neuroscience. 23:1631-1637
The robotic mouse is an autosomal dominant mutant that arose from a large-scale chemical mutagenesis program. It has a jerky, ataxic gait and develops adult-onset Purkinje cell loss in the cerebellum in a striking region-specific pattern, as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a866aea54e0f9ab6dd06a2acd2b6134e
https://doi.org/10.1523/jneurosci.23-05-01631.2003
https://doi.org/10.1523/jneurosci.23-05-01631.2003
Publikováno v:
Human Molecular Genetics. 9:2403-2408
The development of detailed single nucleotide polymorphism (SNP) maps of the human genome coupled with high-throughput genotyping technologies may allow us to unravel complex genetic traits, such as multifactorial disease or drug response, over the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1cdcad1c72075986e885fcb93d1e726
https://doi.org/10.1093/hmg/9.16.2403
https://doi.org/10.1093/hmg/9.16.2403