Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ian C, Miller"'
Autor:
Andrea Santiago, Mark R. Prausnitz, Ian C. Miller, Andrey V. Romanyuk, Gabriel A. Kwong, Laura O'Farrell, Andrew Tadros, Richard K. Noel
Publikováno v:
Nature Medicine. 26:341-347
Drug delivery to the skin is highly constrained by the stratum corneum barrier layer1. Here, we developed star-shaped particles, termed STAR particles, to dramatically increase skin permeability. STAR particles are millimeter-scale particles made of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05189ca8be376e7e23334e6254999e6e
https://doi.org/10.1038/s41591-020-0787-6
https://doi.org/10.1038/s41591-020-0787-6
Autor:
Ian C. Miller, Saul J. Priceman, Gabriel A. Kwong, Hathaichanok Phuengkham, Jason Yang, Adrian M Harris, John P. Murad, Lee-Kai Sun, Ali Zamat, Lena Gamboa
Publikováno v:
Nat Biomed Eng
Treating solid malignancies with chimeric antigen receptor (CAR) T cells typically results in poor responses. Immunomodulatory biologics delivered systemically can augment the cells’ activity, but off-target toxicity narrows the therapeutic window.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c71a24664fbc2f8673572ecb2aeaa7
https://pubmed.ncbi.nlm.nih.gov/34385695
https://pubmed.ncbi.nlm.nih.gov/34385695
The limited ability to control anti-tumor activity within tumor sites contributes to poor CAR T cell responses against solid malignancies. Systemic delivery of biologic drugs such as cytokines can augment CAR T cell activity despite off-target toxici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e18204f8ed585268e8089c7bcd9d910
https://doi.org/10.1101/2020.04.26.062703
https://doi.org/10.1101/2020.04.26.062703
Autor:
Haoxin Li, Gabriel A. Kwong, Lena Gamboa, Ian C. Miller, Erick V. Phung, Jared P. Meyers, Anna C Hart
CRISPR-associated proteins (Cas) are enabling powerful new approaches to control mammalian cell functions, yet the lack of spatially defined, noninvasive modalities limits their use as biological tools. Here, we integrate thermal gene switches with d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e65d996d2d84b475e00aee7326f3fb
https://europepmc.org/articles/PMC7035993/
https://europepmc.org/articles/PMC7035993/
Publikováno v:
ACS synthetic biology. 7(4)
Engineered T cells are transforming broad fields in biomedicine, yet our ability to control cellular activity at specific anatomical sites remains limited. Here we engineer thermal gene switches to allow spatial and remote control of transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7879cc96bde8397c9de1fc9ba8ca143d
https://pubmed.ncbi.nlm.nih.gov/29579381
https://pubmed.ncbi.nlm.nih.gov/29579381
Autor:
Bill Pennington, Yueyuan Zhang, Raz Jelinek, Inyee Han, Paul A. Dawson, Ian C. Miller, Julie K. Northcutt, Timothy W. Hanks
Publikováno v:
Food chemistry. 221
Polydiacetylene (PDA) vesicles are of interest as biosensors, particularly for pathogenic bacteria. As part of a food monitoring system, interaction with food sanitizers/surfactants was investigated. PDA vesicles were prepared by inkjet-printing, pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d4be2222cbfbff3f92c81b489503e6
https://pubmed.ncbi.nlm.nih.gov/27979235
https://pubmed.ncbi.nlm.nih.gov/27979235