Zobrazeno 1 - 10
of 253
pro vyhledávání: '"Ian Bradbury"'
Autor:
Neil Cody, MB, ChB, Ian Bradbury, PhD, Ross R. McMullan, MB, ChB, Gerard Quinn, RN, Aisling O’Neill, RN, Kathryn Ward, RN, Justine McCann, RN, Daniel F. McAuley, MD, Jonathan A. Silversides, PhD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 5, p e1094 (2024)
OBJECTIVES:. Near-infrared spectroscopy (NIRS) is a potentially valuable modality to monitor the adequacy of oxygen delivery to the brain and other tissues in critically ill patients, but little is known about the physiologic determinants of NIRS-der
Externí odkaz:
https://doaj.org/article/c9190e9d9223405b8e3a1ad1565ee2e5
Autor:
Andrew James Boyle, Peter Ferris, Ian Bradbury, John Conlon, Manu Shankar-Hari, Angela J. Rogers, Cecilia M. O’Kane, Daniel F. McAuley
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-8 (2022)
Abstract Background Interleukin (IL)-18 is a marker of inflammasome activation, and high baseline plasma IL-18 is associated with increased mortality in patients with sepsis-induced ARDS. The aim of this analysis was to determine if simvastatin was a
Externí odkaz:
https://doaj.org/article/ace2c777a9024f91bfe027b49ebdca6b
Autor:
John F. R. Robertson, Angelo Di Leo, Stephen Johnston, Stephen Chia, Judith M. Bliss, Robert J. Paridaens, Jasmine Lichfield, Ian Bradbury, Christine Campbell
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract Endocrine therapy (ET) is recommended as first-line therapy for the majority of patients with hormone receptor-positive (HR+), human epidermal growth factor 2-negative advanced breast cancer (ABC); however, the efficacy of ET in patients wit
Externí odkaz:
https://doaj.org/article/d7d894e65aa140f485dd6e6e9833028a
Autor:
Amy K. Teffer, Jonathan Carr, Amy Tabata, Angela Schulze, Ian Bradbury, Denise Deschamps, Carole-Anne Gillis, Eric B. Brunsdon, Gideon Mordecai, Kristina M. Miller
Publikováno v:
FACETS, Vol 5, Pp 234-263 (2020)
A molecular assessment of infectious agents carried by Atlantic salmon at sea and in three eastern Canadian rivers, including aquaculture escapees and North American and European origin wild stocks
Externí odkaz:
https://doaj.org/article/fe762cbf55184fe6a26632e8129503ff
Autor:
Jackie Lighten, Danny Incarnato, Ben J. Ward, Cock van Oosterhout, Ian Bradbury, Mark Hanson, Paul Bentzen
Publikováno v:
Royal Society Open Science, Vol 3, Iss 10 (2016)
The relative importance of genetic versus epigenetic changes in adaptive evolution is a hotly debated topic, with studies showing that some species appear to be able to adapt rapidly without significant genetic change. Epigenetic mechanisms may be pa
Externí odkaz:
https://doaj.org/article/d86ed928d1a84332ae273f50c1faf5e9
Autor:
Katherine O'Neill, Judy M Bradley, Elinor Johnston, Stephanie McGrath, Leanne McIlreavey, Stephen Rowan, Alastair Reid, Ian Bradbury, Gisli Einarsson, J Stuart Elborn, Michael M Tunney
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126980 (2015)
Anaerobic bacteria have been identified in abundance in the airways of cystic fibrosis (CF) subjects. The impact their presence and abundance has on lung function and inflammation is unclear. The aim of this study was to investigate the relationship
Externí odkaz:
https://doaj.org/article/b3d87d187760444095a64518573e4b99
Autor:
Katherine O’Neill, Gokul R. Lakshmipathy, Curtis Neely, Denise Cosgrove, Kathryn Ferguson, Rebecca McLeese, Adam T. Hill, Michael R. Loebinger, Mary Carroll, James D. Chalmers, Timothy Gatheral, Chris Johnson, Anthony De Soyza, John R. Hurst, Ian Bradbury, Joseph S. Elborn, Judy M. Bradley
Publikováno v:
O'Neill, K, Lakshmipathy, G R, Neely, C, Cosgrove, D, Ferguson, K, McLeese, R, Hill, A T, Loebinger, M R, Carroll, M P, Chalmers, J D, Gatheral, T, Johnson, C, de Soyza, A, Hurst, J R, Bradbury, I, Elborn, J S & Bradley, J M 2022, ' Multiple breath washout outcome measures in adults with bronchiectasis ', Annals of the American Thoracic Society, vol. 19, no. 9, pp. 1489-1497 . https://doi.org/10.1513/AnnalsATS.202006-584OC
Ann Am Thorac Soc
Ann Am Thorac Soc
RATIONALE: Lung clearance index (LCI) has good intravisit repeatability with better sensitivity in detecting lung disease on computed tomography scan compared with forced expiratory volume in 1 second (FEV(1)) in adults with bronchiectasis. Alternati
Autor:
José Baselga, Martine Piccart, Evandro de Azambuja, Javier Cortes, Joaquin Arribas, Holger Eidtmann, Catherine Ellis, Lajos Pusztai, Nadia Harbeck, Claudia Aura, José Jimenez, Ludmila Prudkin, Josep Lluis Parra, Violeta Serra, John Winslow, Ahmed Chenna, Christine Campbell, Dominique Agbor-Tarh, Jeff Sperinde, Ian Bradbury, Paolo Nuciforo, Maurizio Scaltriti
Supplementary Table S1. Multivariate Models in the IHC 3+ Subgroup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957f7fdf73f5a4fe582600f5b6fb01be
https://doi.org/10.1158/1078-0432.22455398
https://doi.org/10.1158/1078-0432.22455398
Autor:
José Baselga, Martine Piccart, Evandro de Azambuja, Javier Cortes, Joaquin Arribas, Holger Eidtmann, Catherine Ellis, Lajos Pusztai, Nadia Harbeck, Claudia Aura, José Jimenez, Ludmila Prudkin, Josep Lluis Parra, Violeta Serra, John Winslow, Ahmed Chenna, Christine Campbell, Dominique Agbor-Tarh, Jeff Sperinde, Ian Bradbury, Paolo Nuciforo, Maurizio Scaltriti
Purpose: Expression of p95HER2 has been associated with resistance to trastuzumab-based therapy in patients with metastatic breast cancer. Conversely, high levels of HER2 have been linked with increased clinical benefit from anti-HER2 therapy. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162144fb3b8668cd010809687d11883e
https://doi.org/10.1158/1078-0432.c.6523019.v1
https://doi.org/10.1158/1078-0432.c.6523019.v1
Autor:
José Baselga, Martine Piccart, Evandro de Azambuja, Javier Cortes, Joaquin Arribas, Holger Eidtmann, Catherine Ellis, Lajos Pusztai, Nadia Harbeck, Claudia Aura, José Jimenez, Ludmila Prudkin, Josep Lluis Parra, Violeta Serra, John Winslow, Ahmed Chenna, Christine Campbell, Dominique Agbor-Tarh, Jeff Sperinde, Ian Bradbury, Paolo Nuciforo, Maurizio Scaltriti
Supplementary Figure S1. Distribution of HER2 expression (measured by HERmark) in all patients (left) and in 3+ IHC cohort patients (right). All patient: n=324; IHC3+: n=232.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653996e5aefa1a00efb039bb23a0d470
https://doi.org/10.1158/1078-0432.22455401.v1
https://doi.org/10.1158/1078-0432.22455401.v1