Výsledky vyhledávání - "Ian B. Spurr"

Akademický článek

Total Synthesis of Annonaceous Acetogenins Belonging to the Non-Adjacent Bis-THF and Non-Adjacent THF-THP Sub-Classes

Autor: Richard C. D. Brown, Ian B. Spurr

Publikováno v: Molecules, Vol 15, Iss 1, Pp 460-501 (2010)

The synthesis of the subgroups of acetogenins containing non-adjacent bis-THF and non-adjacent THF-THP core units is reviewed. Specifically, total syntheses of gigantecin, 4-deoxygigantecin, cis-sylvaticin, squamostatin-C, squamostatin-D, sylvaticin

Externí odkaz: https://doaj.org/article/8852c9f27d3440759ef87e51cdd6c9a7

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Targeting Tumour Proliferation with a Small-Molecule Inhibitor of AICAR Transformylase Homodimerization

Autor: Charles N. Birts, Stephen J. Benkovic, Ali Tavassoli, Ian B. Spurr, Jeremy P. Blaydes, F. Cuda

Publikováno v: ChemBioChem. 13:1628-1634

Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) is a bifunctional homodimeric enzyme that catalyzes the last two steps of de novo purine biosynthesis. Homodimerization of ATIC, a protein-protein in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::530b6b87baf7c4a3344202f39517a00b
https://doi.org/10.1002/cbic.201200279

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