Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ian Ager"'
Autor:
Ronald Knegtel, Ian Ager, Luca Settimo, Stephen Clinton Young, Dean Boyall, Richele K Rasmussen, Claire M. Bolton, Peter Chiu, Adam P. Curnock, Christopher John Davis, Adam Tanner, Juan-Miguel Jimenez, Damien Fraysse
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(14)
The identification of a novel series of PKCθ inhibitors and subsequent optimization using docking based on a crystal structure of PKCθ is described. SAR was rapidly generated around an amino pyridine-ketone hit; (6-aminopyridin-2-yl)(2-aminopyridin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dcb8517f1186f9dfe4bbe54db055a35
https://pubmed.ncbi.nlm.nih.gov/22738630
https://pubmed.ncbi.nlm.nih.gov/22738630
Autor:
IAN AGER, DEREK H. R. BARTON, DAVID G. T. GREIG, GINO LUCENTE, PETER G. SAMMES, MICHAEL V. TAYLOR, GRAHAM H. HEWITT, BRIAN E. LOOKER, ANN MOWATT, CAROLINE A. ROBSON, WILLIAM G. E. UNDERWOOD
Publikováno v:
Chemischer Informationsdienst. 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64554cdf926abbe539416f73aa52aa2f
https://doi.org/10.1002/chin.197334444
https://doi.org/10.1002/chin.197334444