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pro vyhledávání: '"Ian A. P. Thompson"'
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
Previous design strategies for pH sensitive aptamers were not readily tunable across pH ranges. Here the authors present a general method to convert aptamers into pH-responsive switches using two orthogonal motifs.
Externí odkaz:
https://doaj.org/article/a24a2adf9c434bc799e6e407a56532c7
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Aptamer switches are promising biotechnological tools but coupling of their affinity and temporal response limits their versatility. Here, the authors developed an intramolecular strand-displacement strategy that allows for independent fine-tuning of
Externí odkaz:
https://doaj.org/article/0ba91a767197432caebcff4ce0b2b98c
Autor:
Amani A. Hariri, Alyssa P. Cartwright, Constantin Dory, Yasser Gidi, Steven Yee, Kaiyu Fu, Kiyoul Yang, Diana Wu, Ian A. P. Thompson, Nicolò Maganzini, Trevor Feagin, Brian E. Young, Behrad Habib Afshar, Michael Eisenstein, Michel Digonnet, Jelena Vuckovic, H. Tom Soh
Current technology for measuring specific biomarkers – continuously in complex samples, without sample preparation – is limited to just handful of molecules such as glucose and blood oxygen. In this work, we present the first optical biosensor sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53384f8ef1ef6e4d53c28d5c41d226d6
https://doi.org/10.1101/2023.03.03.531030
https://doi.org/10.1101/2023.03.03.531030
Autor:
Mark Friedel, Ian A. P. Thompson, Gerald Kasting, Ronen Polsky, David Cunningham, Hyongsok Tom Soh, Jason Heikenfeld
Publikováno v:
Nature Biomedical Engineering.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7fdc6478139f0c31fc31f0f3ec13477
https://doi.org/10.1038/s41551-022-00998-9
https://doi.org/10.1038/s41551-022-00998-9
Autor:
Tuan Trinh, Ian A. P. Thompson, Finley Clark, Jacob M. Remington, Michael Eisenstein, Jianing Li, H. Tom Soh
DNA switches that can change conformation in response to certain wavelengths of light could enable rapid and non-invasive control of chemical processes for a wide range of applications. However, most current photo-responsive DNA switches are limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11e3649ccbd0ea7151c8f9e346462327
https://doi.org/10.1101/2022.05.22.492975
https://doi.org/10.1101/2022.05.22.492975
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
Nature Communications
Nature Communications
Aptamer switches that respond sensitively to pH could enhance control over molecular devices, improving their diagnostic and therapeutic efficacy. Previous designs have inserted pH-sensitive DNA motifs into aptamer sequences. Unfortunately, their per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3e8b2b6178228875eebcbefe81b04e
https://doaj.org/article/a24a2adf9c434bc799e6e407a56532c7
https://doaj.org/article/a24a2adf9c434bc799e6e407a56532c7
Publikováno v:
Daily Mail; 7/26/2022, p1, 3p