Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ian A. Marozas"'
Publikováno v:
Tissue Eng Part A
Characterizing the release profile for materials-directed local delivery of bioactive molecules and its effect on bone regeneration is an important step to improve our understanding of, and ability to optimize, the bone healing response. This study e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489a3e4d78e14e07a976775ccdf838c7
https://doi.org/10.1089/ten.tea.2020.0119
https://doi.org/10.1089/ten.tea.2020.0119
Publikováno v:
New Journal of Physics, Vol 21, Iss 4, p 045004 (2019)
Human mesenchymal stem cells (hMSCs) sense and respond to the bulk elastic and viscoelastic properties of their microenvironment, as well as the spatial distribution of these mechanical signals. Hydrogel substrates with photo-controlled mechanical pr
Externí odkaz:
https://doaj.org/article/2401027ad9284726813ac61f20900b0e
Autor:
Tobin E. Brown, F. Max Yavitt, Brady T. Worrell, Kemal Arda Günay, Christopher N. Bowman, Ian A. Marozas, Kristi S. Anseth, Jason S. Silver
Publikováno v:
Journal of the American Chemical Society. 140:11585-11588
Muscle cells sense the mechanical properties of their microenvironment, and these properties can change in response to injury or disease. Hydrogels with dynamic material properties can be used to study the effect of such varying mechanical signals. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea068cf0c4b6a1264eb30c770338bf74
https://doi.org/10.1021/jacs.8b07551
https://doi.org/10.1021/jacs.8b07551
Autor:
Tzong-Jen Sheu, Steven G. Russell, Christopher S. Schmitt, Danielle S. W. Benoit, J. Edward Puzas, Maureen R. Newman, Ian A. Marozas
Publikováno v:
Biomacromolecules. 19:71-84
Drug delivery to bone is challenging, whereby drug distribution is commonly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4783dcc1e75d7ae7120d767a4e16c8a0
https://doi.org/10.1021/acs.biomac.7b01193
https://doi.org/10.1021/acs.biomac.7b01193
Autor:
Leonora Abdullahu, Stuart A. McNelles, Alex Adronov, Ian A. Marozas, Sabrina M. Hodgson, Kristi S. Anseth
Publikováno v:
Biomacromolecules. 18:4054-4059
A common issue with hydrogel formulations is batch-to-batch irreproducibility originating from poorly defined polymer precursors. Here, we report the use of dendritic polymer end-groups to address this issue and maintain reproducibility between batch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003fa2c739960768182f374cb7023239
https://doi.org/10.1021/acs.biomac.7b01115
https://doi.org/10.1021/acs.biomac.7b01115
Publikováno v:
ACS Macro Letters, 5(1), 19-23. American Chemical Society
Photodriven click reactions have emerged as versatile tools for biomaterial synthesis that can recapitulate critical spatial and temporal changes of extracellular matrix (ECM) microenvironments in vitro. In this article, we report on the synthesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22bd85aaddc7b79d7b6362bfeb9026d9
https://doi.org/10.1021/acsmacrolett.5b00682
https://doi.org/10.1021/acsmacrolett.5b00682
Publikováno v:
Biomaterials
Cells are capable of sensing the differences in elastic and viscous properties (i.e., the ‘viscoelasticity’) of their tissue microenvironment and responding accordingly by changing their transcriptional activity and modifying their behaviors. Whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b67c760de24c6eb47662f4ac66e187a0
https://doi.org/10.1016/j.biomaterials.2019.119430
https://doi.org/10.1016/j.biomaterials.2019.119430
Publikováno v:
New Journal of Physics. 21:045004
Human mesenchymal stem cells (hMSCs) sense and respond to the bulk elastic and viscoelastic properties of their microenvironment, as well as the spatial distribution of these mechanical signals. Hydrogel substrates with photo-controlled mechanical pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9c877c6ac937e4964316c68bca68786
https://doi.org/10.1088/1367-2630/ab1309
https://doi.org/10.1088/1367-2630/ab1309
Publikováno v:
Advanced materials (Deerfield Beach, Fla.). 29(11)
Hydrogels crosslinked by allyl-sulfide-containing molecules are presented. By exposure to light in the presence of a photoinitiator and a free monofunctional thiol, photodegradation is achieved. Both the gelation and degradation are cytocompatible an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca3a757f18a30b42f004ba3b6765c950
https://pubmed.ncbi.nlm.nih.gov/28112845
https://pubmed.ncbi.nlm.nih.gov/28112845
Hydrogels have emerged as promising scaffolds in regenerative medicine for the delivery of biomolecules to promote healing. However, increasing evidence suggests that the context that biomolecules are presented to cells (e.g., as soluble verses tethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb361f3e4af6e89996c7817f67cb6494
https://europepmc.org/articles/PMC4656112/
https://europepmc.org/articles/PMC4656112/
