Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Ian A. Carr"'
Publikováno v:
Bioinformatics and Biology Insights, Vol 18 (2024)
Gene ontology phrases are a widely used set of hierarchical terms that describe the biological properties of genes. These terms are then used to annotate individual genes, making it possible to determine the likely physiological properties of groups
Externí odkaz:
https://doaj.org/article/bf82eb50506349bab87c2f83b0ee78cb
Autor:
Elizabeth Boyse, Kevin P. Robinson, Maria Beger, Ian M. Carr, Morag Taylor, Elena Valsecchi, Simon J. Goodman
Publikováno v:
Environmental DNA, Vol 6, Iss 4, Pp n/a-n/a (2024)
Abstract Marine mammal foraging grounds are popular focal points for marine protected area (MPA) implementation, despite being temporally dynamic, requiring continuous monitoring to infer prey availability and abundance. Marine mammal distributions a
Externí odkaz:
https://doaj.org/article/7787dba621254b8c8871d97c32777585
Autor:
Antonios Psarras, Adewonuola Alase, Agne Antanaviciute, Ian M. Carr, Md Yuzaiful Md Yusof, Miriam Wittmann, Paul Emery, George C. Tsokos, Edward M. Vital
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Type I interferon drives autoimmune pathology in SLE and has been assumed to come predominantly from plasmacytoid dendritic cells (pDCs). Here, the authors show that prior to the onset of SLE, pDCs lose multiple immunogenic functions and, instead, no
Externí odkaz:
https://doaj.org/article/bbb2318833484129bd8e0fdec78640c3
Autor:
Mark A. Hull, Richard J. Cuthbert, C. W. Stanley Ko, Daniel J. Scott, Elizabeth J. Cartwright, Gillian Hawcroft, Sarah L. Perry, Nicola Ingram, Ian M. Carr, Alexander F. Markham, Constanze Bonifer, P. Louise Coletta
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Genetic deletion or pharmacological inhibition of cyclooxygenase (COX)-2 abrogates intestinal adenoma development at early stages of colorectal carcinogenesis. COX-2 is localised to stromal cells (predominantly macrophages) in human and mous
Externí odkaz:
https://doaj.org/article/e481426f4bf8467fae7994ac44635d17
Autor:
Belinda Baquero-Perez, Agne Antanaviciute, Ivaylo D Yonchev, Ian M Carr, Stuart A Wilson, Adrian Whitehouse
Publikováno v:
eLife, Vol 8 (2019)
N6-methyladenosine (m6A) is the most abundant internal RNA modification of cellular mRNAs. m6A is recognised by YTH domain-containing proteins, which selectively bind to m6A-decorated RNAs regulating their turnover and translation. Using an m6A-modif
Externí odkaz:
https://doaj.org/article/8f45fcf9731d40a1852c8fa1a6403483
Autor:
Aidyn Kydyrmanov, Kobey Karamendin, Yermukhammet Kassymbekov, Marat Kumar, Shynar Mazkirat, Symbat Suleimenova, Mirgaliy Baimukanov, Ian M. Carr, Simon J. Goodman
Publikováno v:
Frontiers in Marine Science. 10
Disease surveillance of marine mammal populations is essential to understand the causes of strandings, identify potential threats to animal health, and to support development of conservation strategies. Here we report the first large multi-pathogen s
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192170 (2018)
Epigenetic marks such as DNA methylation and histone modification can vary among plant accessions creating epi-alleles with different levels of expression competence. Mutations in epigenetic pathway functions are powerful tools to induce epigenetic v
Externí odkaz:
https://doaj.org/article/42460f72fff84912b010417dc4ba1402
Autor:
Kobey Karamendin, Aidyn Kydyrmanov, Yermukhammet Kasymbekov, Saule Asanova, Klara Daulbayeva, Aigerim Seidalina, Elizaveta Khan, Sally M Harrison, Ian M Carr, Simon J Goodman, Alibek Moldakozhayev, Marat Sayatov
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0190339 (2017)
Three isolates APMV/gull/Kazakhstan/5976/2014, APMV/gull/Kazakhstan/ 5977/2014 and APMV/gull/Kazakhstan/5979/2014, were obtained from independent samples during annual surveillance for avian influenza and paramyxoviruses in wild birds from the Caspia
Externí odkaz:
https://doaj.org/article/d074f5ce41b343899d787e923eba718f
Autor:
David T. Bonthron, Rachel Robinson, Rowena E. Mitchell, Christopher M. Watson, Sérgio D.J. Pena, George A. Tanteles, Laura A. Crinnion, Helen Lindsay, Ian M. Carr, Nick Camm, Domhnall J. O' Halloran, Caroline Joyce
Publikováno v:
Laboratory Investigation. 101:442-449
Short-read next generation sequencing (NGS) has become the predominant first-line technique used to diagnose patients with rare genetic conditions. Inherent limitations of short-read technology, notably for the detection and characterization of compl
Autor:
Christopher W. Wasson, Jörg H W Distler, Clarissa Corinaldesi, Rebecca L. Ross, Agne Antanaviciute, Clive S. McKimmie, Francesco Del Galdo, Yasser M. El-Sherbiny, Steve Holmes, Antonio Carriero, Ian M. Carr, Gemma Migneco
Publikováno v:
Annals of the Rheumatic Diseases
ObjectivesPlasmacytoid dendritic cells (pDC) have been implicated in the pathogenesis of autoimmune diseases, such as scleroderma (SSc). However, this has been derived from indirect evidence using ex vivo human samples or mouse pDC in vivo. We have d