Zobrazeno 1 - 10
of 326
pro vyhledávání: '"Ian A Rowe"'
Autor:
Harriet Hunter, Dana de Gracia Hahn, Amedine Duret, Yu Ri Im, Qinrong Cheah, Jiawen Dong, Madison Fairey, Clarissa Hjalmarsson, Alice Li, Hong Kai Lim, Lorcan McKeown, Claudia-Gabriela Mitrofan, Raunak Rao, Mrudula Utukuri, Ian A Rowe, Jake P Mann
Publikováno v:
eLife, Vol 9 (2020)
The classical drug development pipeline necessitates studies using animal models of human disease to gauge future efficacy in humans, however there is a low conversion rate from success in animals to humans. Non-alcoholic fatty liver disease (NAFLD)
Externí odkaz:
https://doaj.org/article/e3d2a6b4f51e4f3e833552afae4730a8
Autor:
William Bernal, Rhiannon Taylor, Ian A. Rowe, Abhishek Chauhan, Matthew J. Armstrong, Michael E.D. Allison, Gwilym Webb, Tasneem Pirani, Joanna Moore, Laura Burke, Steven Masson, David Cressy, Brian J. Hogan, Rachel Westbrook, Rajiv Jalan, Kenneth J. Simpson, John Isaac, Douglas Thorburn
Publikováno v:
The Lancet Regional Health. Europe, Vol 46, Iss , Pp 101067- (2024)
Summary: Background: Acute on Chronic Liver Failure (ACLF) complicates chronic liver disease (CLD) combining rapidly progressive hepatic with extra-hepatic multiple organ failure and high short-term mortality. Effective therapeutic options are very l
Externí odkaz:
https://doaj.org/article/adaca2eb8cbe453daf3287fe0f7ea985
Publikováno v:
Annals of Hepatology, Vol 29, Iss 5, Pp 101528- (2024)
Introduction and Objectives: Despite the huge clinical burden of MASLD, validated tools for early risk stratification are lacking, and heterogeneous disease expression and a highly variable rate of progression to clinical outcomes result in prognosti
Externí odkaz:
https://doaj.org/article/9b27871896cb41348b9b52c97fc36d22
Autor:
Graeme Alexander, Deborah Fitzsimmons, Mari Jones, Anya Burton, Aileen Marshall, Lizz Paley, Daniela Tataru, Katherine Cullen, Rhys D. Pockett, Timothy J.S. Cross, Ian A. Rowe
Publikováno v:
BMJ Open Gastroenterology, Vol 10, Iss 1 (2023)
Objective Hepatocellular carcinoma (HCC) incidence in the UK trebled between 1997 and 2017. With increasing numbers requiring treatment, understanding the likely impact on healthcare budgets can inform service planning and commissioning. The aim of t
Externí odkaz:
https://doaj.org/article/e511ebcab3314f1eaf84adf11d32d518
Publikováno v:
Case Studies in Chemical and Environmental Engineering, Vol 7, Iss , Pp 100353- (2023)
Alluvial small-scale gold mining (ASGM) mining in the Amazon is expanding fiercely, generating severe environmental degradation, which includes the fast disappearance of primary forests in a highly biodiverse area of the world. Different factors moti
Externí odkaz:
https://doaj.org/article/9394dd559371495fad7c52b25da5ab49
Publikováno v:
BMC Sports Science, Medicine and Rehabilitation, Vol 14, Iss 1, Pp 1-11 (2022)
Abstract Background Athletic underperformance is characterized by fatigue and an inability to sustain a consistent exercise workload. We describe five elite swimmers with prolonged fatigue and athletic underperformance. Based on our work in myalgic e
Externí odkaz:
https://doaj.org/article/65533a4f891847bcb02800f3706d96dc
Publikováno v:
Ecological Indicators, Vol 129, Iss , Pp 107918- (2021)
Purpose: Marine litter, mostly plastics, is a growing environmental problem. Environmental decision makers are beginning to take actions and implement regulations that aim to reduce plastic use and waste mismanagement. Nevertheless, life cycle assess
Externí odkaz:
https://doaj.org/article/60f0f23da0374710b59eae26d9da2436
Autor:
Namy Espinoza Orias, Christian John Reynolds, Alexi Sara Ernstoff, Ian Vázquez-Rowe, Karen Cooper, Rubén Aldaco
Publikováno v:
Frontiers in Nutrition, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/9fc741c78f6f47969839865147f9444b
Autor:
Anya Burton, Daniela Tataru, Robert J. Driver, Thomas G. Bird, Dyfed Huws, David Wallace, Timothy J.S. Cross, Ian A. Rowe, Graeme Alexander, Aileen Marshall, Ian Rowe, Vinay Kumar, Tim Cross, Katherine Cullen, Rhys Pockett, Tom Bird, Dyfed W. Huws, Anna Gavin, Lizz Paley, Guruprasad Aithal
Publikováno v:
JHEP Reports, Vol 3, Iss 2, Pp 100232- (2021)
Background & Aims: The incidence of primary liver cancer (PLC) is increasing in Western Europe. To understand trends over time and the current burden in the UK, a detailed analysis of the epidemiology of PLC and its subtypes was conducted. Methods: D
Externí odkaz:
https://doaj.org/article/2651ea993c1844779a66723628a0627f
Publikováno v:
Climate Risk Management, Vol 33, Iss , Pp 100329- (2021)
Assessing disaster impacts is the pathway to attain informed decision making to mitigate damages. Currently, these impacts are generally analyzed excluding the environmental consequences of disasters. Thus, this study proposes a novel quantitative me
Externí odkaz:
https://doaj.org/article/07ca6adbdbf046999cb272ed17c09028