Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Ian A, Prior"'
Autor:
Rachel J. Carter, Mateus Milani, Alison J. Beckett, Shiyu Liu, Ian A. Prior, Gerald M. Cohen, Shankar Varadarajan
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-13 (2022)
Abstract The recruitment of DRP1 to mitochondrial membranes prior to fission is facilitated by the wrapping of endoplasmic reticulum (ER) membranes around the mitochondria. To investigate the complex interplay between the ER membranes and DRP1 in the
Externí odkaz:
https://doaj.org/article/18a54fa33ee1436389ec7df75e673145
Publikováno v:
BMC Chemistry, Vol 15, Iss 1, Pp 1-13 (2021)
Abstract Background Local sequence context is known to have an impact on the mutational pattern seen in cancer. The RAS genes and a smoking carcinogen, Benzo[a]pyrene diol epoxide (BPDE), have been utilised to explore these context effects. BPDE is k
Externí odkaz:
https://doaj.org/article/fac036fe53d44a0ba48df6cf8840a89b
Autor:
Luca Barbieri, Ioritz Sorzabal Bellido, Alison J. Beckett, Ian A. Prior, Jo Fothergill, Yuri A. Diaz Fernandez, Rasmita Raval
Publikováno v:
npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract In this work, we introduce a one-step strategy that is suitable for continuous flow manufacturing of antimicrobial PDMS materials. The process is based on the intrinsic capacity of PDMS to react to certain organic solvents, which enables the
Externí odkaz:
https://doaj.org/article/8f77af64df2c4764bceea6855eeb3e44
Autor:
Matheus H. Dias, Cecília S. Fonseca, Julianna D. Zeidler, Layra L. Albuquerque, Marcelo S. daSilva, Eduardo Cararo‐Lopes, Marcelo S. Reis, Vincent Noël, Edmilson O. dosSantos, Ian A. Prior, Hugo A. Armelin
Publikováno v:
Molecular Oncology, Vol 13, Iss 2, Pp 290-306 (2019)
In malignant transformation, cellular stress‐response pathways are dynamically mobilized to counterbalance oncogenic activity, keeping cancer cells viable. Therapeutic disruption of this vulnerable homeostasis might change the outcome of many human
Externí odkaz:
https://doaj.org/article/a0f2218e8b7245598d3649ce9e9b7bc0
Autor:
Dilip C Badgujar, Anjali Anil, Angharad E Green, Manalee Vishnu Surve, Shilpa Madhavan, Alison Beckett, Ian A Prior, Barsa K Godsora, Sanket B Patil, Prachi Kadam More, Shruti Guha Sarkar, Andrea Mitchell, Rinti Banerjee, Prashant S Phale, Timothy J Mitchell, Daniel R Neill, Prasenjit Bhaumik, Anirban Banerjee
Publikováno v:
PLoS Pathogens, Vol 16, Iss 11, p e1009016 (2020)
The opportunistic pathogen Streptococcus pneumoniae has dual lifestyles: one of an asymptomatic colonizer in the human nasopharynx and the other of a deadly pathogen invading sterile host compartments. The latter triggers an overwhelming inflammatory
Externí odkaz:
https://doaj.org/article/70810cc3f0074720881ffa86572128e8
Autor:
Ioritz Sorzabal-Bellido, Luca Barbieri, Alison J. Beckett, Ian A. Prior, Arturo Susarrey-Arce, Roald M. Tiggelaar, Joanne Fothergill, Rasmita Raval, Yuri A. Diaz Fernandez
Publikováno v:
Nanomaterials, Vol 12, Iss 4, p 683 (2022)
Surface engineering is a promising strategy to limit or prevent the formation of biofilms. The use of topographic cues to influence early stages of biofilm formationn has been explored, yet many fundamental questions remain unanswered. In this work,
Externí odkaz:
https://doaj.org/article/26d03d3b7cac4a04a32f8483766dd67f
Autor:
Piersandro Pallavicini, Barbara Bassi, Giuseppe Chirico, Maddalena Collini, Giacomo Dacarro, Emiliano Fratini, Pietro Grisoli, Maddalena Patrini, Laura Sironi, Angelo Taglietti, Marcel Moritz, Ioritz Sorzabal-Bellido, Arturo Susarrey-Arce, Edward Latter, Alison J. Beckett, Ian A. Prior, Rasmita Raval, Yuri A. Diaz Fernandez
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Photo-responsive antibacterial surfaces combining both on-demand photo-switchable activity and sustained biocidal release were prepared using sequential chemical grafting of nano-objects with different geometries and functions. The multi-lay
Externí odkaz:
https://doaj.org/article/45d4719b81a24f5b8da726eca04ccd5a
Publikováno v:
The Biochemical journal
Approximately 15% of all cancer patients harbor mutated KRAS. Direct inhibitors of KRAS have now been generated and are beginning to make progress through clinical trials. These include a suite of inhibitors targeting the KRASG12C mutation commonly f
Publikováno v:
Biology Open, Vol 8, Iss 5 (2019)
The rapid evolution of super-resolution light microscopy has narrowed the gap between light and electron microscopy, allowing the imaging of molecules and cellular structures at high resolution within their normal cellular and tissue context. Multimo
Externí odkaz:
https://doaj.org/article/60fc86192d194f498fdb26d5bb800aaf
Autor:
Ian A. Prior, Patrick A. Eyers, Paul D. Smith, Joseph R. Slupsky, Sarah J. Ross, David J. MacEwan, Judy M. Coulson, Fiona E. Hood, Dean E. Hammond, Adam Linley, Leah J. Wilson
Supplementary legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1585a1aebff8194ce43c53a9a6a0314a
https://doi.org/10.1158/0008-5472.22416558
https://doi.org/10.1158/0008-5472.22416558