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Akademický článek

USP7 controls NGN3 stability and pancreatic endocrine lineage development

Autor: Teodora Manea, Jessica Kristine Nelson, Cristina Maria Garrone, Karin Hansson, Ian Evans, Axel Behrens, Rocio Sancho

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)

Abstract Understanding the factors and mechanisms involved in beta-cell development will guide therapeutic efforts to generate fully functional beta cells for diabetes. Neurogenin 3 (NGN3) is the key transcription factor that marks endocrine progenit

Externí odkaz: https://doaj.org/article/659513cc4feb44a297984081dccc3d55

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Akademický článek

Effect of ambient lighting on frequency dependence in transcranial electrical stimulation-induced phosphenes

Autor: Ian Evans, Stephen Palmisano, Rodney J. Croft

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)

Abstract Inconsistencies have been found in the relationship between ambient lighting conditions and frequency-dependence in transcranial electric stimulation (tES) induced phosphenes. Using a within-subjects design across lighting condition (dark, m

Externí odkaz: https://doaj.org/article/407994515ed542c5bb0bb7341d7e2c32

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Akademický článek

Increase in the use of inhaled nitric oxide in neonatal intensive care units in England: a retrospective population study

Autor: Chris Gale, Jonathan Cusack, Sanjay Salgia, Peter Martin, Matthew Babirecki, Liza Harry, Tim Wickham, Aashish Gupta, L M Wong, Anita Mittal, Sunita Seal, Ahmed Hassan, Karin Schwarz, Graham Whincup, Stephen Brearey, John Chang, Abdul Hasib, Mehdi Garbash, David Gibson, Pauline Adiotomre, Abby Deketelaere, Ruth Shephard, Mukta Jain, Stanley Zengeya, Cath Seagrave, Hilary Dixon, Narendra Aladangady, Hassan Gaili, Matthew James, M Lal, Ambadkar, Khalid Mannan, Lawrence Miall, Venkatesh Kairamkonda, J Kefas, Jennifer Birch, Gail Whitehead, I Misra, Imdad Ali, Mark Dyke, Michael Selter, Subodh Gupta, Richard Nicholl, Steven Wardle, Eleri Adams, Minesh Khashu, P Amess, Charlotte Groves, Shameel Mattara, Christos Zipitis, Peter De Halpert, Paul Settle, Paul Munyard, Joanne Fedee, Natasha Maddock, Richa Gupta, Stephen Jones, Kirsten Mack, Charlotte Huddy, Ngozi Edi-osagie, Nick Brennan, Carrie Heal, Majd Abu-harb, Jacqeline Birch, Chris Knight, Hamudi Kisat, Hari Kumar, Chris Rawlingson, Delyth Webb, Bird, Sankara Narayanan, Ian Evans, Rekha Sanghavi, Caroline Sullivan, Wynne Leith, Vimal Vasu, Katia Vamvakiti, Megan Eaton, Vadivelam Murthy, Aiwyne Foo, Katharine Mcdevitt, Shu-Ling Chuang, Cheryl Battersby, Nimish V Subhedar, Sena Jawad, Tristan Bate, Mark Johnson, Neeraj Jain, Faith Emery, Vineet Gupta, Yee Aung, Pinki Surana, Kayleigh Oughham, Anand Kamalanathan, Kavi Aucharaz, Nicola Paul, Lindsay Halpern, Matt Nash, Jo Anderson, Alex Allwood, Nigel Brooke, K Abdul Khader, Sanghavi Rekha, Anas Olabi, Jennifer Holman, Geraint Lee, Sobia Balal, Poornima Pandey, Ravindra Bhat, Simon Rhodes, Vinay Pai, Savi Sivashankar, Michael Grosdenier, Ajay Reddy, Christopher Dewhurst, Ghada Ramadan Krishnamurthy, Rob Negrine, Prakash Thiagarajan, P Kamath, Laura Winder, Andreea Bontea, Chinnappa Reddy, Elizabeth Sleight Deshpande, Lidia Tyszcuzk, Anne Dale, Glynis Rewitzky, Olutoyin Banjoko, Bushra Abdul-Malik, Dominic Muogbo, Angela D'Amore, John McIntyre, Chrissie Oliver, Lucinda Winckworth, Jyoti Kapur, P Amess Ben Obi, Naveen Athiraman, Chandan Gupta, Jim Baird, Ralf Hartung, Akinsola Ogundiya, Pamela Cairns, Porus Bastani, Marice Theron, Siba Paul, Giles Kendall, Puneet Nath, Ozioma Obi, Yee Mon Aung, Eleanor Hulse, Ros Garr, Sundeep Sandhu

Publikováno v: BMJ Paediatrics Open, Vol 5, Iss 1 (2021)

Objective To describe temporal changes in inhaled nitric oxide (iNO) use in English neonatal units between 2010 and 2015.Design Retrospective analysis using data extracted from the National Neonatal Research Database.Setting All National Health Servi

Externí odkaz: https://doaj.org/article/51e7e032e2fb49fbab90dde43b1e1173

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Akademický článek

PARP1 Inhibitor Combined With Oxaliplatin Efficiently Suppresses Oxaliplatin Resistance in Gastric Cancer-Derived Organoids via Homologous Recombination and the Base Excision Repair Pathway

Autor: Huafu Li, Chunming Wang, Linxiang Lan, Wenhui Wu, Ian Evans, E. Josue Ruiz, Leping Yan, Zhijun Zhou, Joaquim M. Oliveira, Rui L. Reis, Zhenran Hu, Wei Chen, Axel Behrens, Yulong He, Changhua Zhang

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Oxaliplatin (OXA) resistance in the treatment of different types of cancer is an important and complex problem. The culture of tumor organoids derived from gastric cancer can help us to provide a deeper understanding of the underlying mechanisms that

Externí odkaz: https://doaj.org/article/1a708a1fd2ea485db52e0b41bef62450

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Safer children, healthier lives: reducing the burden of serious accidents to children

Autor: Ian, Evans

Publikováno v: Paediatrics and Child Health. 32:302-306

COVID-19 has placed huge pressures on clinicians and front line practitioners across the UK. The focus has been, understandably, on the day to day challenges that the pandemic has brought. But lockdown measures have also put a spotlight on safety in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c6f09af6532f861098ed84a499a75f
https://doi.org/10.1016/j.paed.2022.05.004

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