Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Ian, Cheong"'
Autor:
Rongji Sum, Sylvester Jian Ming Lim, Ajitha Sundaresan, Sudipta Samanta, Muthukaruppan Swaminathan, Wayne Low, Madhumitha Ayyappan, Ting Wei Lim, Marvin Dragon Choo, Gabriel Junming Huang, Ian Cheong
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Clostridium septicum infections are highly predictive of certain malignancies in human patients. To initiate infections, C. septicum spores must first germinate and regain vegetative growth. Yet, what triggers the germination of C. septicum
Externí odkaz:
https://doaj.org/article/05cde37edf0640dba55e059814ad3d24
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 8, Iss , Pp 100287- (2023)
Introduction: Candida albicans is an important and widespread opportunistic pathogen. In recent years, studies have found that traditional Chinese medicine (TCM) can inhibit the growth of various types of fungi without inducing drug resistance. This
Externí odkaz:
https://doaj.org/article/b6d4966352bb4f488708398e0e7bd6e2
Autor:
Ajitha Sundaresan, Mai Le Ngoc, Marvell Ung Wew, Varsha Ramkumar, Prahlad Raninga, Rongji Sum, Ian Cheong
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
A screen for germination of Clostridium novyi-NT spores reveals that germinant sensing of this tumor-destructive anaerobic bacterium is stereoflexible for valine and its analogs and identifies co-germinants to improve germination efficacy in tumors.
Externí odkaz:
https://doaj.org/article/f3bf4aa474d94ad49d90e51b24dca205
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Proton pump inhibitors (PPIs) were found to be associated with depression. This study aimed to find the cross-sectional association between recent PPI use and suicidal ideation. Item 9 of Patient Health Questionnaire-9 (PHQ-9) of the US Nati
Externí odkaz:
https://doaj.org/article/36b983149c984e21ae46a0beb8a4c520
Autor:
Pratibha Bhai, Benjamin Chin-Yee, Victor Pope, Ian Cheong, Maxim Matyashin, Michael A. Levy, Aidin Foroutan, Alan Stuart, Cyrus C. Hsia, Hanxin Lin, Bekim Sadikovic, Ian Chin-Yee
Publikováno v:
Current Oncology, Vol 29, Iss 10, Pp 7209-7217 (2022)
Background: Since the identification of JAK2 V617F and exon 12 mutations as driver mutations in polycythemia vera (PV) in 2005, molecular testing of these mutations for patients with erythrocytosis has become a routine clinical practice. However, the
Externí odkaz:
https://doaj.org/article/3f897fc6e5724f84ae1912b24b087ec4
Autor:
Veronica Rendo, Ivaylo Stoimenov, André Mateus, Elin Sjöberg, Richard Svensson, Anna-Lena Gustavsson, Lars Johansson, Adrian Ng, Casey OʼBrien, Marios Giannakis, Per Artursson, Peter Nygren, Ian Cheong, Tobias Sjöblom
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Allelic losses occurring in cancer cells have been suggested as potential targets for therapy. Here, the authors show how recurring loss of heterozygosity of a drug metabolic gene in colorectal cancers can be exploited using a low molecular weight co
Externí odkaz:
https://doaj.org/article/f0524ece03f240dd980cb46a0462a392
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232755 (2020)
The quality control of intracellular proteins is achieved by degrading misfolded proteins which cannot be refolded by molecular chaperones. In eukaryotes, such degradation is handled primarily by the ubiquitin-proteasome system. However, it remained
Externí odkaz:
https://doaj.org/article/4a865fd316094096851c71c262bae1d3
Publikováno v:
Neurological Sciences. 44:2209-2211
Autor:
Benjamin, Chin-Yee, Maxim, Matyashin, Ian, Cheong, Pratibha, Bhai, Alejandro, Lazo-Langner, Ala, Almanaseer, Eri, Kawata, Michael A, Levy, Alan, Stuart, Hanxin, Lin, Ian, Chin-Yee, Bekim, Sadikovic, Cyrus, Hsia
Publikováno v:
CMAJ Open. 10:E988-E992
Molecular testing foriJAK2/imutations is part of the standard diagnostic workup for patients with suspected polycythemia vera. We sought to characterize evolving practice patterns in the investigation of erythrocytosis and the prevalence of secondary
Autor:
Sudipta Samanta, Muthukaruppan Swaminathan, Jianing Hu, Khai Tuck Lee, Ajitha Sundaresan, Chuan Keng Goh, Chor Hiang Siow, Kwok Seng Loh, Soh Ha Chan, Joshua K. Tay, Ian Cheong
Publikováno v:
The American Journal of Pathology. 192:1295-1304