Single-Cell Analysis Uncovers Striking Cellular Heterogeneity of Lung-Infiltrating Regulatory T Cells during Eosinophilic versus Neutrophilic Allergic Airway Inflammation.

Autor: Iamsawat S; Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL., Yu R; Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL., Kim S; Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL., Dvorina N; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH., Qiu K; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL., Choi J; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL., Baldwin WM 3rd; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH., Min B; Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2024 Jun 15; Vol. 212 (12), pp. 1867-1876.

Cutting Edge: Steroid Responsiveness in Foxp3 ⁺ Regulatory T Cells Determines Steroid Sensitivity during Allergic Airway Inflammation in Mice.

Autor: Nguyen QT; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH., Kim D; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH.; Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL., Iamsawat S; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH.; Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL., Le HT, Kim S, Qiu KT; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL., Hinds TD, Bazeley P, O'Shea JJ, Choi J, Asosingh K, Erzurum SC, Min B; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH; booki.min@northwestern.edu.; Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2021 Aug 01; Vol. 207 (3), pp. 765-770. Date of Electronic Publication: 2021 Jul 23.

RNA binding protein PCBP1 is an intracellular immune checkpoint for shaping T cell responses in cancer immunity.

Autor: Ansa-Addo EA; Department of Microbiology and Immunology and Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA.; Pelotonia Institute for Immuno-Oncology and Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center-James, Columbus, OH 43210, USA., Huang HC; Department of Microbiology and Immunology and Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA.; National Taiwan University College of Medicine, Graduate Institute of Clinical Medicine, No.7 Chung San South Road, Taipei City 10002, Taiwan., Riesenberg B; Department of Microbiology and Immunology and Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA.; Pelotonia Institute for Immuno-Oncology and Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center-James, Columbus, OH 43210, USA., Iamsawat S; Department of Microbiology and Immunology and Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA., Borucki D; Department of Microbiology and Immunology and Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA., Nelson MH; Department of Microbiology and Immunology and Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA., Nam JH; Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC 29425, USA., Chung D; Pelotonia Institute for Immuno-Oncology and Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center-James, Columbus, OH 43210, USA.; Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC 29425, USA., Paulos CM; Department of Microbiology and Immunology and Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA., Liu B; Department of Microbiology and Immunology and Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA., Yu XZ; Department of Microbiology and Immunology and Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA., Philpott C; Genetics and Metabolism Section, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Bethesda, MD 20892, USA., Howe PH; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29425, USA., Li Z; Department of Microbiology and Immunology and Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA.; Pelotonia Institute for Immuno-Oncology and Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center-James, Columbus, OH 43210, USA.

Publikováno v: Science advances [Sci Adv] 2020 May 29; Vol. 6 (22), pp. eaaz3865. Date of Electronic Publication: 2020 May 29 (Print Publication: 2020).

Sirt1: An Increasingly Interesting Molecule with a Potential Role in Bone Metabolism and Osteoporosis.

Autor: Chen, Yi^1,2,3 (AUTHOR) chenyi2021@lzu.edu.cn, Xiao, Hefang^1,2,3 (AUTHOR) 120220901471@lzu.edu.cn, Liu, Zirui^1,2,3 (AUTHOR) l1993070501@126.com, Teng, Fei^1,2,3 (AUTHOR) lzu_1909@126.com, Yang, Ao^1,2,3 (AUTHOR) ya12021090111@126.com, Geng, Bin^1,2,3 (AUTHOR) ldeygb2008@126.com, Sheng, Xiaoyun^1,2,3 (AUTHOR) shengxy20@lzu.edu.cn, Xia, Yayi^1,2,3 (AUTHOR) shengxy20@lzu.edu.cn

Publikováno v: Biomolecules (2218-273X). Aug2024, Vol. 14 Issue 8, p970. 23p.

Thioredoxin-1 improves the immunometabolic phenotype of antitumor T cells.

Autor: Chakraborty P; From the Departments of Surgery., Chatterjee S; From the Departments of Surgery., Kesarwani P; From the Departments of Surgery., Thyagarajan K; From the Departments of Surgery., Iamsawat S; Microbiology and Immunology., Dalheim A; the Department of Surgery, Loyola University, Maywood, Illinois 60153, and., Nguyen H; Microbiology and Immunology., Selvam SP; Biochemistry and Molecular Biology., Nasarre P; From the Departments of Surgery., Scurti G; the Department of Surgery, Loyola University, Maywood, Illinois 60153, and., Hardiman G; Nephrology., Maulik N; the Department of Surgery, University of Connecticut Health Center, Farmington, Connecticut 06030., Ball L; Pharmaceutical and Biomedical Sciences, and., Gangaraju V; Biochemistry and Molecular Biology., Rubinstein MP; From the Departments of Surgery., Klauber-DeMore N; From the Departments of Surgery., Hill EG; Public Health, Hollings Cancer Center, Medical University of South Carolina, Charleston, South Carolina 29425., Ogretmen B; Biochemistry and Molecular Biology., Yu XZ; Microbiology and Immunology., Nishimura MI; the Department of Surgery, Loyola University, Maywood, Illinois 60153, and., Mehrotra S; From the Departments of Surgery, mehrotr@musc.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2019 Jun 07; Vol. 294 (23), pp. 9198-9212. Date of Electronic Publication: 2019 Apr 10.