Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Iain Welsby"'
Autor:
Maurizio Ceppi, Gregory Driessens, Bart Claes, Stephanie Ma, Olivier De Henau, Julia Cuende, Iain Welsby, Nicolas Rosewick, Noemie Wald, Anais Vezzu, Marjorie Mercier, Paola Tieppo, Yvonne McGrath, Marion Libouban
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/9d8b5927cc014339990ab7bf0d70b99d
Autor:
Julia Cuende, Julie Preillon, Noemie Wald, Marjorie Mercier, Paola Tieppo, Iain Welsby, Veronique Bodo, Yvonne McGrath, Tom F. Van Den Mooter, Jean-Pascal Machiels, Clarisse Truong, Olivier De Henau, Gregory Driessens, Marion Libouban
Publikováno v:
Cancer Research. 82:LB189-LB189
T cell immunoglobulin and ITIM domain (TIGIT) is an immune checkpoint inhibitor expressed mainly on NK and T cell populations which has demonstrated clinical proof of concept in NSCLC for its inhibition in combination with a-PD(L)-1 agents1. EOS-448
Publikováno v:
Immunology. 149:329-342
Lactobacillus acidophilus induces a potent interferon‐β (IFN‐β) response in dendritic cells (DCs) by a Toll‐like receptor 2 (TLR2) ‐dependent mechanism, in turn leading to strong interleukin‐12 (IL‐12) production. In the present study,
Autor:
Stanislas Goriely, Oberdan Leo, Séverine Thomas, Iain Welsby, Marjorie Vermeersch, Catherine Collignon, Viviana Lima Silva, Céline Molle, David Perez-Morga, Sophie Detienne, Romain Gineste, Arnaud M. Didierlaurent, Charlotte Givord, Assiya Assabban
Publikováno v:
NPJ Vaccines, Vol. 3 (2018) P. 20
npj Vaccines, Vol 3, Iss 1, Pp 1-12 (2018)
NPJ vaccines, 3 (1
NPJ Vaccines
npj Vaccines, Vol 3, Iss 1, Pp 1-12 (2018)
NPJ vaccines, 3 (1
NPJ Vaccines
The oil-in-water emulsion Adjuvant System 03 (AS03) is one of the few adjuvants used in licensed vaccines. Previous work indicates that AS03 induces a local and transient inflammatory response that contributes to its adjuvant effect. However, the mol
Autor:
Patricia Bourguignon, Catherine Collignon, Stanislas Goriely, Age K. Smilde, Sandra Morel, Bart N. Lambrecht, Caroline Hervé, Iain Welsby, Margherita Coccia, Mary J. van Helden, Arnaud M. Didierlaurent, Sophie Detienne, Robert A. van den Berg, Sheetij Dutta, Nathalie Garçon, Christopher J. Genito, Robbert van der Most, Aurélie Chalon, Katrijn Van Deun, David Franco, Norman C. Waters
Publikováno v:
NPJ vaccines, 2
npj Vaccines, 2:25. Nature Publishing Group
NPJ VACCINES
npj Vaccines, Vol 2, Iss 1, Pp 1-14 (2017)
NPJ Vaccines
NPJ Vaccines, Vol. 2 (2017) P. 25
Expert Review of Vaccines, 2:25. Taylor and Francis Ltd.
npj Vaccines, 2:25. Nature Publishing Group
NPJ VACCINES
npj Vaccines, Vol 2, Iss 1, Pp 1-14 (2017)
NPJ Vaccines
NPJ Vaccines, Vol. 2 (2017) P. 25
Expert Review of Vaccines, 2:25. Taylor and Francis Ltd.
Combining immunostimulants in adjuvants can improve the quality of the immune response to vaccines. Here, we report a unique mechanism of molecular and cellular synergy between a TLR4 ligand, 3-O-desacyl-4’-monophosphoryl lipid A (MPL), and a sapon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1741104b4913e94d587a82f9a497ef57
https://lirias.kuleuven.be/handle/123456789/620882
https://lirias.kuleuven.be/handle/123456789/620882
Publikováno v:
Journal of Biological Chemistry. 289:26642-26657
Transcriptome analyses have recently identified PARP12, a member of a large family of ADP-ribosyl transferases, as an interferon-induced gene (ISG), whose function remains incompletely characterized. We demonstrate herein that PARP12 is a genuine ISG
Autor:
Sophie Delhaye, Catherine Collignon, Iain Welsby, Laurye Van Maele, Sophie Detienne, Abdelatif Elouahabi, Sandrine Wouters, Stanislas Goriely, Arnaud M. Didierlaurent, Maëlle Swertvaegher, Séverine Thomas, Aurélie Detavernier, Maria Elisabetta M.E. Coccia
Publikováno v:
Scientific reports, 6
Scientific Reports
Scientific Reports
Saponins represent a promising class of vaccine adjuvant. Together with the TLR4-ligand MPL, QS-21 is part of the Adjuvant System AS01, a key component of the malaria and zoster candidate vaccines that display demonstrated clinical efficacy. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9313424778a3881b351a96c03eac319e
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/242047
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/242047
Autor:
Stanislas Goriely, Iain Welsby
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9789402409192
Interleukin (IL)-23 plays a central role in the orchestration of inflammatory responses. Produced by dendritic cells and macrophages, this cytokine promotes the protection of the host against mucosal pathogens through the induction of IL-17 and relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f6556323766b45d873a21ec4f7fa41
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/316302
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/316302
Autor:
Iain, Welsby, Stanislas, Goriely
Publikováno v:
Advances in experimental medicine and biology. 941
Interleukin (IL)-23 plays a central role in the orchestration of inflammatory responses. Produced by dendritic cells and macrophages, this cytokine promotes the protection of the host against mucosal pathogens through the induction of IL-17 and relat
Autor:
Stanislas Goriely, Pierre J. Courtoy, Abdelatif Elouahabi, Dominique De Wit, Séverine Thomas, Francisca N'Kuli, Romain Gineste, Arnaud M. Didierlaurent, Viviane Bechtold, Sophie Detienne, Iain Welsby, Sandrine Wouters, Thomas Reinheckel
Publikováno v:
Frontiers in Immunology
Frontiers in immunology, 7
Frontiers in immunology, Vol. 7, p. 663 (2017)
Frontiers in Immunology, Vol. 7 (2017) P. 663
Frontiers in immunology, 7
Frontiers in immunology, Vol. 7, p. 663 (2017)
Frontiers in Immunology, Vol. 7 (2017) P. 663
The adjuvant properties of the saponin QS-21 have been known for decades. It is a component of the Adjuvant System AS01 that is used in several vaccine candidates. QS-21 strongly potentiates both cellular and humoral immune responses to purified anti