Zobrazeno 1 - 10
of 1 083
pro vyhledávání: '"Iain S McGregor"'
Autor:
Iain S McGregor, Richard Fox, Hamish MacDougall, Danielle McCartney, Zeeta Bawa, Miguel Bedoya-Pérez, Namson S Lau
Publikováno v:
BMJ Open, Vol 14, Iss 3 (2024)
Introduction The non-intoxicating plant-derived cannabinoid, cannabidiol (CBD), has demonstrated therapeutic potential in a number of clinical conditions. Most successful clinical trials have used relatively high (≥300 mg) oral doses of CBD. Relati
Externí odkaz:
https://doaj.org/article/9248e73d295142a9baec102e4d90af5a
Autor:
Brendon J Yee, Ronald R Grunstein, Christopher J Gordon, Anastasia Suraev, Nathaniel S Marshall, Angela L D'Rozario, Delwyn J Bartlett, Keith Wong, Ryan Vandrey, Chris Irwin, Jonathon C Arnold, Iain S McGregor, Camilla M Hoyos
Publikováno v:
BMJ Open, Vol 10, Iss 5 (2020)
Introduction Insomnia is a highly prevalent and costly condition that is associated with increased health risks and healthcare utilisation. Anecdotally, cannabis use is frequently reported by consumers to promote sleep. However, there is limited rese
Externí odkaz:
https://doaj.org/article/60a0e6e5c2df4c14b67eb6abec2220c2
Autor:
Menna E Jones, Raimund Apfelbach, Peter B. Banks, Elissa Z Cameron, Chris R Dickman, Anke Frank, Stuart McLean, Iain S McGregor, Dietland Muller-Schwarze, Michael H. Parsons, Elisa Sparrow, Daniel T Blumstein
Publikováno v:
Frontiers in Ecology and Evolution, Vol 4 (2016)
Non-lethal management of wildlife, both ‘problem wildlife’ and pest species, to protect crops and threatened species is becoming increasingly important as non-human animals and humans come into closer proximity. A particularly promising approach
Externí odkaz:
https://doaj.org/article/8fc7dc521ab544429d5534a42fb0d034
Autor:
Tristan P. Hurzeler, Warren Logge, Joshua Watt, Marilena M. DeMayo, Anastasia Suraev, Iain S. McGregor, Paul S. Haber, Kirsten C. Morley
Publikováno v:
Contemporary Clinical Trials Communications, Vol 41, Iss , Pp 101341- (2024)
Current treatments for alcohol use disorders (AUD) have limited efficacy. Recently, Cannabidiol (CBD) has been examined in a multitude of clinical settings. Preclinical and clinical results suggest that CBD might be particularly well suited for the t
Externí odkaz:
https://doaj.org/article/5c89802e2e8b4bcb892f84402e5745b5
Autor:
Emily Aspasia Karanges, Mohammed A Kashem, Ranjana eSarker, Eakhlas U Ahmed, Selina eAhmed, Petra evan Nieuwenhuijzen, Andrew H Kemp, Iain S McGregor
Publikováno v:
Frontiers in Pharmacology, Vol 4 (2013)
Selective serotonin reuptake inhibitors (SSRIs) are commonly recognised as the pharmacological treatment of choice for patients with depressive disorders, yet their use in adolescent populations has come under scrutiny following reports of minimal ef
Externí odkaz:
https://doaj.org/article/83b9cfdc520e4c43856a05a8a0773312
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70052 (2013)
Recent analysis of the cannabinoid content of cannabis plants suggests a shift towards use of high potency plant material with high levels of Δ(9)-tetrahydrocannabinol (THC) and low levels of other phytocannabinoids, particularly cannabidiol (CBD).
Externí odkaz:
https://doaj.org/article/912f1f8e80dc4fb0b8e876ba52de3d65
Autor:
Michael T Bowen, Richard C Kevin, Matthew May, Lauren G Staples, Glenn E Hunt, Iain S McGregor
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68483 (2013)
Aggregation is a defensive strategy employed by many prey species in response to predatory threat. Our group has characterized defensive aggregation (huddling) in Rattus norvegicus in response to a ball of cat fur. In this situation some rats huddle
Externí odkaz:
https://doaj.org/article/54adbd9e995f4dcf8d5bc9137b2ad0e7
Autor:
Craig P Motbey, Emily Karanges, Kong M Li, Shane Wilkinson, Adam R Winstock, John Ramsay, Callum Hicks, Michael D Kendig, Naomi Wyatt, Paul D Callaghan, Iain S McGregor
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45473 (2012)
Mephedrone (4-methylmethcathinone, MMC) is a popular recreational drug, yet its potential harms are yet to be fully established. The current study examined the impact of single or repeated MMC exposure on various neurochemical and behavioral measures
Externí odkaz:
https://doaj.org/article/64e0f058b7d54634bd898e7984ee7e5d
Autor:
Leonora E Long, Rose Chesworth, Xu-Feng Huang, Alexander Wong, Adena Spiro, Iain S McGregor, Jonathon C Arnold, Tim Karl
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34129 (2012)
The cannabis constituent cannabidiol (CBD) possesses anxiolytic and antipsychotic properties. We have previously shown that transmembrane domain neuregulin 1 mutant (Nrg1 TM HET) mice display altered neurobehavioural responses to the main psychoactiv
Externí odkaz:
https://doaj.org/article/69c3ecc4cc634d11bc40653edef597cb
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27237 (2011)
Previous studies have suggested that administration of oxytocin (OT) can have modulatory effects on social and anxiety-like behavior in mammals that may endure beyond the time of acute OT administration. The current study examined whether repeated ad
Externí odkaz:
https://doaj.org/article/688e9bea44914497910f03a59cca10cd