Interprofessional, student-led intervention to improve insulin prescribing to patients in an Acute Surgical Receiving Unit

Autor: Iona Campbell, Vicki Tully, Suaad Al-Salti, Iain Rowe, Amy Arnold, Peter Davey, Rachel Fane, Shady Botros, Alison Strath

Publikováno v: BMJ Open Quality

Our aim was to test the feasibility of interprofessional, workplace-based learning about improvement through a 4-week placement for one medical and two pharmacy final year students in an Acute Surgical Receiving Unit (ASRU). The target was insulin be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e66e965600ab19b970a11fa99aa8ce6
https://pubmed.ncbi.nlm.nih.gov/30019012

Palmitoylation of the S0-S1 Linker Regulates Cell Surface Expression of Voltage- and Calcium-activated Potassium (BK) Channels

Autor: Iain Rowe, Heather McClafferty, Nina Geiger, H.-G. Knaus, Owen Jeffries, Lijun Tian, Peter Ruth, Danlei Bi, Michael J. Shipston, Lie Chen

Publikováno v: The Journal of Biological Chemistry
Jeffries, O, Geiger, N, Rowe, I C M, Tian, L J, McClafferty, H, Chen, L, Bi, D L, Knaus, H G, Ruth, P & Shipston, M J 2010, ' Palmitoylation of the S0-S1 Linker Regulates Cell Surface Expression of Voltage-and Calcium-activated Potassium (BK) Channels ', Journal of Biological Chemistry, vol. 285, no. 43, pp. 33307-33314 . https://doi.org/10.1074/jbc.M110.153940

S-Palmitoylation is rapidly emerging as an important post-translational mechanism to regulate ion channels. We have previously demonstrated that large conductance calcium-and voltage-activated potassium (BK) channels are palmitoylated within an alter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee08b4545c3db20696eef3bd87aa2629
https://doi.org/10.1074/jbc.m110.153940

CD31 delays phagocyte membrane repolarization to promote efficient binding of apoptotic cells

Autor: Lijun Tian, Simon B. Brown, Frédéric Auradé, Elizabeth F. Vernon-Wilson, Michael J. Shipston, Iain Rowe, John Savill

Publikováno v: Journal of Leukocyte Biology. 82:1278-1288

Homophilic ligation of CD31, a member of the Ig superfamily of adhesion receptors, promotes macrophage clearance of apoptotic leukocytes by a mechanism hitherto not described. In studying CD31-dependent regulation of β1-integrin binding of fibronect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41227bd230b26fb78180253b54133fdd
https://doi.org/10.1189/jlb.0507283

Lysosomal Calcium: Impact on Serotonin‐Induced Contractions of Ovine Pulmonary Arteries

Autor: Amy Arnold, Lorna Linklater, Iain Rowe, Helene Widmer, Stuart F. Cruickshank

Publikováno v: The FASEB Journal. 29

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f062eb47083fffab70880b89aeab6304
https://doi.org/10.1096/fasebj.29.1_supplement.804.3

NS 1619 activates BKCa channel activity in rat cortical neurones

Autor: Iain Rowe, Michael L.J. Ashford, Kevin Lee

Publikováno v: European Journal of Pharmacology. 280:215-219

Single channel recordings of large conductance Ca2(+)-activated K+ (BKCa) channels were made from neurones isolated from rat motor cortex. Application of levcromakalim, pinacidil or diazoxide had no effect on BKCa channel activity in excised patches.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::091f992978548ecc6dea3da7d80202ba
https://doi.org/10.1016/0014-2999(95)00251-f