Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Iain P Chessell"'
Autor:
Katie H. Barker, James P. Higham, Luke A. Pattison, Iain P. Chessell, Fraser Welsh, Ewan St. J. Smith, David C. Bulmer
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 324:G250-G261
The pro-inflammatory cytokine interleukin-13 (IL-13) is elevated in gastrointestinal (GI) diseases. This study confirms a role for IL-13 in colonic afferent sensitization and defines a role for downstream Janus kinase (JAK) and p38 MAPK signaling in
Autor:
Tarik Khaznadar, Helen Susanne Price, Andy Billinton, Martin E. Swarbrick, David Andrew Stevens, Gerard Martin Paul Giblin, Melanie A. Kay, Anton D. Michel, Nicholas Maughan Clayton, David J. Spalding, Alan Naylor, Alex W. Wilson, Amanda C. Allan, Mark Patrick Healy, Iain P. Chessell, Kristin Bailey
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:1892-1896
A novel series of EP4 agonists and antagonists have been identified, and then used to validate their potential in the treatment of inflammatory pain. This paper describes these novel ligands and their activity within a number of pre-clinical models o
Autor:
Freija ter Heegde, Ana P. Luiz, Sonia Santana-Varela, Iain P. Chessell, Fraser Welsh, John N. Wood, Chantal Chenu
Publikováno v:
Arthritis & Rheumatology
Autor:
Mark P, Healy, Amanda C, Allan, Kristin, Bailey, Andy, Billinton, Iain P, Chessell, Nicholas M, Clayton, Gerard M P, Giblin, Melanie A, Kay, Tarik, Khaznadar, Anton D, Michel, Alan, Naylor, Helen, Price, David J, Spalding, David A, Stevens, Martin E, Swarbrick, Alexander W, Wilson
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(10)
A novel series of EP
Autor:
Phil Newton, Michael S. Perkinton, Maria Groves, Tristan J. Vaughan, Anna Bogstedt, Iain P. Chessell, Amanda Dudley, Fraser Welsh, Chris Lloyd, Rajesh Narwal, Keith Tan, Mary McFarlane, Andy Billinton, Susanna Eketjäll
Publikováno v:
Alzheimer's & Dementia. 13
Autor:
Tomas Ondrejcak, Andy Billinton, Dominic M. Walsh, Maria Groves, Michael S. Perkinton, Tiernan T. O'Malley, Iain P. Chessell, Michael J. Rowan, Amanda Dudley
Publikováno v:
Alzheimer's & Dementia. 13
Autor:
Thor Ostenfeld, Richard Turner, Eva Lindqvist, Amanda Dudley, Iain P. Chessell, Michael Pomfret, Manasa Tatipalli, Rajesh Narwal, Nancy Y. Lee, Maria Groves, Andy Billinton, Keith Tan, Zulma Santisteban Valencia, Tharani Chessell
Publikováno v:
Alzheimer's & Dementia. 13
Autor:
Praveen Anand, C. Bountra, Uma Anand, Rolfe Birch, Iain P. Chessell, Marco Sinisi, William R. Otto
BACKGROUND: Cytosine arabinoside (Ara C) is a useful chemotherapy agent, used for treating acute myeloid leukaemia, although it may be associated with side effects including painful neuropathy. It is also used for in vitro neuronal studies to limit t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e710c573285d2f89fd82d115b71a7b9
https://ora.ox.ac.uk/objects/uuid:d17f34a3-ba74-4bd5-99ee-0a868dec6953
https://ora.ox.ac.uk/objects/uuid:d17f34a3-ba74-4bd5-99ee-0a868dec6953
Autor:
Iain P. Chessell, Nick M. Clayton, John N. Haselden, Mark P. Hodson, C. Bountra, Susan C. Connor, Royston A. Gray
The objective measurement of chronic pain in pre-clinical animal models and in the clinical arena is problematic. The multifactorial nature of pain can adversely affect the accuracy with which it can be quantitatively assessed. This is due to diverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d20c012385b94d9f6d8d190fa8549ae
https://ora.ox.ac.uk/objects/uuid:0e65e5b1-c65b-4eb2-8173-d53d17203d99
https://ora.ox.ac.uk/objects/uuid:0e65e5b1-c65b-4eb2-8173-d53d17203d99