Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Iain M Hagan"'
Autor:
Danny A Bitton, Agnes Grallert, Paul J Scutt, Tim Yates, Yaoyong Li, James R Bradford, Yvonne Hey, Stuart D Pepper, Iain M Hagan, Crispin J Miller
Publikováno v:
Molecular Systems Biology, Vol 7, Iss 1, Pp 1-21 (2011)
Abstract Strand‐specific RNA sequencing of S. pombe revealed a highly structured programme of ncRNA expression at over 600 loci. Waves of antisense transcription accompanied sexual differentiation. A substantial proportion of ncRNA arose from mecha
Externí odkaz:
https://doaj.org/article/b1f542a7605441ed97ce001219cc0aae
Autor:
Dorota Fennessy, Agnes Grallert, Andrea Krapp, Adisa Cokoja, Alan J Bridge, Janni Petersen, Avinash Patel, Victor A Tallada, Elvan Boke, Ben Hodgson, Viesturs Simanis, Iain M Hagan
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97683 (2014)
Targeted alteration of the genome lies at the heart of the exploitation of S. pombe as a model system. The rate of analysis is often determined by the efficiency with which a target locus can be manipulated. For most loci this is not a problem, howev
Externí odkaz:
https://doaj.org/article/235d5d63b75a4bfaa23576a3e88ecda1
Autor:
Elvan Boke, Iain M Hagan
Publikováno v:
PLoS Genetics, Vol 7, Iss 8, p e1002213 (2011)
Externí odkaz:
https://doaj.org/article/5c4a1b42220144cba63cbda73299ea38
Autor:
Kaitlin R. Morrison, Tingting Wang, Kuan Yoow Chan, Eleanor W. Trotter, Ari Gillespie, Michael Z. Michael, Jonathan S. Oakhill, Iain M. Hagan, Janni Petersen
Publikováno v:
Open Biology, Vol 13, Iss 4 (2023)
Expression and activity of the AMP-activated protein kinase (AMPK) α1 catalytic subunit of the heterotrimeric kinase significantly correlates with poor outcome for colorectal cancer patients. Hence there is considerable interest in uncovering signal
Externí odkaz:
https://doaj.org/article/8f517fb0f4714e258cf9dc1d821f5c08
Autor:
Lenka Halova, David Cobley, Mirita Franz-Wachtel, Tingting Wang, Kaitlin R. Morrison, Karsten Krug, Nicolas Nalpas, Boris Maček, Iain M. Hagan, Sean J. Humphrey, Janni Petersen
Publikováno v:
Open Biology, Vol 11, Iss 4 (2021)
Fluctuations in TOR, AMPK and MAP-kinase signalling maintain cellular homeostasis and coordinate growth and division with environmental context. We have applied quantitative, SILAC mass spectrometry to map TOR and nutrient-controlled signalling in th
Externí odkaz:
https://doaj.org/article/52572a9d94fa427cb6902e05c02baba9
Autor:
null Kaitlin R. Morrison, null Tingting Wang, null Kuan Yoow Chan, null Eleanor W. Trotter, null Ari Gillespie, null Michael Z. Michael, null Jonathan S. Oakhill, null Iain M. Hagan, null Janni Petersen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58ca41fc0da7331dd910ac50764426cb
https://doi.org/10.1098/rsob.230021/v2/response1
https://doi.org/10.1098/rsob.230021/v2/response1
Autor:
Karsten Krug, Janni Petersen, Mirita Franz-Wachtel, Kaitlin R. Morrison, David Cobley, Nicolas C. Nalpas, Tingting Wang, Boris Macek, Sean J. Humphrey, Lenka Halova, Iain M. Hagan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5808dbff7542d29c543c069a4e8f039c
https://doi.org/10.1098/rsob.200405/v2/response1
https://doi.org/10.1098/rsob.200405/v2/response1
Publikováno v:
Methods in Molecular Biology ISBN: 9781071615379
Synchronized progression of a cell population through the cell division cycle supports the biochemical and functional dissection of cell cycle controls and execution. The concerted behaviour of the population reflects the attributes of each cell with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ff1fbc740594a8017e35ab71cf47f3c
https://doi.org/10.1007/978-1-0716-1538-6_10
https://doi.org/10.1007/978-1-0716-1538-6_10
Autor:
Wendy Eleanor Trotter, Iain M. Hagan
Publikováno v:
Open Biology, Vol 10, Iss 10 (2020)
Trotter, E W & Hagan, I M 2020, ' Release from cell cycle arrest with Cdk4/6 inhibitors generates highly synchronized cell cycle progression in human cell culture ', Open Biology, vol. 10, no. 10, pp. 200200 . https://doi.org/10.1098/rsob.200200
Open Biology
Trotter, E W & Hagan, I M 2020, ' Release from cell cycle arrest with Cdk4/6 inhibitors generates highly synchronized cell cycle progression in human cell culture ', Open Biology, vol. 10, no. 10, pp. 200200 . https://doi.org/10.1098/rsob.200200
Open Biology
Each approach used to synchronise cell cycle progression of human cell lines presents a unique set of challenges. Induction synchrony with agents that transiently block progression through key cell cycle stages are popular, but change stoichiometries
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d944a2049b1e51a169e8493945d0d96
https://doi.org/10.1098/rsob.200200
https://doi.org/10.1098/rsob.200200
Autor:
Jonathan S. Oakhill, Mirita Franz-Wachtel, Gabriella Forte, Shervi Lie, Iain M. Hagan, Boris Macek, Janni Petersen, Ashley J. Ovens, Elizabeth Davie, Tingting Wang
Publikováno v:
Journal of Cell Science
AMP-activated kinase (AMPK) and target of rapamycin (TOR) signalling coordinate cell growth, proliferation, metabolism and cell survival with the nutrient environment of cells. The poor vasculature and nutritional stress experienced by cells in solid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f5541312f46bf8425985783f0a292c
https://acuresearchbank.acu.edu.au/item/87v4y/import-of-extracellular-atp-in-yeast-and-man-modulates-ampk-and-torc1-signalling
https://acuresearchbank.acu.edu.au/item/87v4y/import-of-extracellular-atp-in-yeast-and-man-modulates-ampk-and-torc1-signalling