Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Iain J, Gallagher"'
Publikováno v:
BMJ Open, Vol 14, Iss 8 (2024)
Background The reporting of randomised controlled non-inferiority (NI) drug trials is poor with less than 50% of published trials reporting a justification of the NI margin. This is despite the introduction of the Consolidated Standards of Reporting
Externí odkaz:
https://doaj.org/article/4f27dc9629884bce85c9aaa21326a0fe
Autor:
Kirstin A. MacGregor, Frederick K. Ho, Carlos A. Celis-Morales, Jill P. Pell, Iain J. Gallagher, Colin N. Moran
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Preliminary evidence demonstrates some parameters of metabolic control, including glycaemic control, lipid control and insulin resistance, vary across the menstrual cycle. However, the literature is inconsistent, and the underlyin
Externí odkaz:
https://doaj.org/article/332710b91fab480cbc6ecb08e4781722
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundIntelectin-1 (ITLN1) is an adipokine with multiple physiological functions, including a role in tumour formation and development. Previous research reported variable ITLN1 levels for cancer patients and healthy individuals. This study aimed
Externí odkaz:
https://doaj.org/article/8bce946cf1104f0f87eb1f2207fe7f26
Autor:
Tanner Stokes, Haoning Howard Cen, Philipp Kapranov, Iain J Gallagher, Andrew A. Pitsillides, Claude‐Henry Volmar, William E Kraus, James D. Johnson, Stuart M. Phillips, Claes Wahlestedt, James A. Timmons
Publikováno v:
Advanced Genetics, Vol 4, Iss 2, Pp n/a-n/a (2023)
Abstract Sequencing the human genome empowers translational medicine, facilitating transcriptome‐wide molecular diagnosis, pathway biology, and drug repositioning. Initially, microarrays are used to study the bulk transcriptome; but now short‐rea
Externí odkaz:
https://doaj.org/article/e905fbd859144cbe92af1c8b24906620
Autor:
D. Robert Paval, Rebekah Patton, James McDonald, Richard J.E. Skipworth, Iain J. Gallagher, Barry J. Laird, the Caledonian Cachexia Collaborative
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 2, Pp 824-838 (2022)
Abstract Cancer cachexia is an unmet clinical need that affects more than 50% of patients with cancer. The systemic inflammatory response, which is mediated by a network of cytokines, has an established role in the genesis and maintenance of cancer a
Externí odkaz:
https://doaj.org/article/2ad9fc380ea84ab6ad9657c61d9093e4
Autor:
Amy E. Mendham, Julia H. Goedecke, Lisa K. Micklesfield, Naomi E. Brooks, Mieke Faber, Dirk L. Christensen, Iain J. Gallagher, Lillemor Lundin-Olsson, Kathryn H. Myburgh, Feyisayo A. Odunitan-Wayas, Estelle V. Lambert, Sebastiana Kalula, Angus M. Hunter
Publikováno v:
BMC Geriatrics, Vol 21, Iss 1, Pp 1-15 (2021)
Abstract Background High rates of food insecurity, obesity and obesity-related comorbidities in ageing South African (SA) women may amplify the risk of developing sarcopenic obesity. This study aimed to investigate the prevalence and correlates of sa
Externí odkaz:
https://doaj.org/article/0f6ea1d525c74fafbe6aeebbf10bd704
Autor:
Janice Miller, Gillian Dreczkowski, Michael I. Ramage, Stephen J. Wigmore, Iain J. Gallagher, Richard J.E. Skipworth
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 4, Pp 1141-1153 (2020)
Abstract Background Cancer cachexia is a poorly understood metabolic consequence of cancer. During cachexia, different adipose depots demonstrate differential wasting rates. Animal models suggest adipose tissue may be a key driver of muscle wasting t
Externí odkaz:
https://doaj.org/article/340e8ab0e8df4799a095196c862120dd
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundIntelectin (ITLN) is an adipokine with two homologs—ITLN1 and ITLN2—that has various physiological functions. Studies analyzing the relationship between ITLN and cancer are focused on ITLN1; the available literature on ITLN2 and cancer
Externí odkaz:
https://doaj.org/article/e9c00192eda247668c9f4c24b47e4a19
Publikováno v:
Frontiers in Sports and Active Living, Vol 3 (2021)
Objectives: The objective of this study was to assess if injury-related alterations in the Sport Concussion Assessment Tool-5 (SCAT5) are matched by changes in transcranial magnetic stimulation-derived intracortical inhibition. We hypothesised that n
Externí odkaz:
https://doaj.org/article/b6e3cc77420a4f3691ba6f0d8368c8e1
Autor:
James A. Timmons, Iain J. Gallagher, Sanjana Sood, Bethan Phillips, Hannah Crossland, Robert Howard, William E. Kraus, Philip J. Atherton
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-4 (2019)
Abstract Jacob and Speed did not identify even a single example of a ‘150-gene-set’ that was statistically significant at classifying Alzheimer’s disease (AD) samples, or age in independent studies. We attempt to clarify the various misundersta
Externí odkaz:
https://doaj.org/article/62128a060b074590976d2841dc214b53