Zobrazeno 1 - 10
of 1 536
pro vyhledávání: '"Iain H."'
Investigating light sensitivity in bipolar disorder (HELIOS-BD) [version 2; peer review: 2 approved]
Autor:
Amber Roguski, Iain H. Campbell, Lyle Armstrong, Amy Ferguson, Baljean Dhillon, Majlinda Lako, Gerrit Hilgen, Jasna Martinovic, Tom MacGillivray, Renata L. Riha, Nicole Needham, Nayantara Santhi, Philipp Ritter, Manuel Spitschan, Malcolm von Schantz, Daniel J. Smith
Publikováno v:
Wellcome Open Research, Vol 9 (2024)
Many people with bipolar disorder have disrupted circadian rhythms. This means that the timing of sleep and wake activities becomes out-of-sync with the standard 24-hour cycle. Circadian rhythms are strongly influenced by light levels and previous re
Externí odkaz:
https://doaj.org/article/c903e42ee15b4fbe8e18c6f8855e8a13
Investigating light sensitivity in bipolar disorder (HELIOS-BD) [version 1; peer review: 2 approved]
Autor:
Amber Roguski, Iain H. Campbell, Lyle Armstrong, Amy Ferguson, Baljean Dhillon, Majlinda Lako, Gerrit Hilgen, Jasna Martinovic, Tom MacGillivray, Renata L. Riha, Nicole Needham, Nayantara Santhi, Philipp Ritter, Manuel Spitschan, Malcolm von Schantz, Daniel J. Smith
Publikováno v:
Wellcome Open Research, Vol 9 (2024)
Many people with bipolar disorder have disrupted circadian rhythms. This means that the timing of sleep and wake activities becomes out-of-sync with the standard 24-hour cycle. Circadian rhythms are strongly influenced by light levels and previous re
Externí odkaz:
https://doaj.org/article/761cc507071142ba9f8d01dcffb2488f
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Antibodies with similar amino acid sequences, especially across their complementarity-determining regions, often share properties. Finding that an antibody of interest has a similar sequence to naturally expressed antibodies in healthy or di
Externí odkaz:
https://doaj.org/article/7972f0972cfa49b39db1c2f1a757735e
Autor:
Nicole Needham, Iain H. Campbell, Helen Grossi, Ivana Kamenska, Benjamin P. Rigby, Sharon A. Simpson, Emma McIntosh, Pankaj Bahuguna, Ben Meadowcroft, Frances Creasy, Maja Mitchell-Grigorjeva, John Norrie, Gerard Thompson, Melissa C. Gibbs, Ailsa McLellan, Cheryl Fisher, Tessa Moses, Karl Burgess, Rachel Brown, Michael J. Thrippleton, Harry Campbell, Daniel J. Smith
Publikováno v:
BJPsych Open, Vol 9 (2023)
Background Recent evidence from case reports suggests that a ketogenic diet may be effective for bipolar disorder. However, no clinical trials have been conducted to date. Aims To assess the recruitment and feasibility of a ketogenic diet interventi
Externí odkaz:
https://doaj.org/article/6c02bf95d0304e498412e6f76ae2ac78
Autor:
Natalia A. Osna, Irina Tikhanovich, Martí Ortega-Ribera, Sebastian Mueller, Chaowen Zheng, Johannes Mueller, Siyuan Li, Sadatsugu Sakane, Raquel Carvalho Gontijo Weber, Hyun Young Kim, Wonseok Lee, Souradipta Ganguly, Yusuke Kimura, Xiao Liu, Debanjan Dhar, Karin Diggle, David A. Brenner, Tatiana Kisseleva, Neha Attal, Iain H. McKillop, Shilpa Chokshi, Ram Mahato, Karuna Rasineni, Gyongyi Szabo, Kusum K. Kharbanda
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 404 (2024)
Alcohol-associated liver disease (ALD) is a substantial cause of morbidity and mortality worldwide and represents a spectrum of liver injury beginning with hepatic steatosis (fatty liver) progressing to inflammation and culminating in cirrhosis. Mult
Externí odkaz:
https://doaj.org/article/142e2cdd280940af8c937a0c17615d54
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract In this paper, we propose that lithium may exert its therapeutic effect in bipolar disorder by acting on insulin signaling pathways. Specifically, we assess the importance of the phosphatidylinositol 3-kinase/Protein Kinase B (PI3K/Akt) insu
Externí odkaz:
https://doaj.org/article/108d454983f6480fb22b770d50229c9c
Autor:
Michael L. Ekaney, Juan Carlos Carrillo-Garcia, Gabrielle Gonzalez-Gray, Hadley H. Wilson, Mary M. Jordan, Iain H. McKillop, Susan L. Evans
Publikováno v:
Cells, Vol 12, Iss 1, p 166 (2022)
Donated platelets are critical components of hemostasis management. Extending platelet storage beyond the recommended guidelines (5 days, 22 °C) is of clinical significance. Platelet coagulation function can be prolonged with resveratrol (Res) or cy
Externí odkaz:
https://doaj.org/article/03d8651ae5254dcd85650b9e4ffddee1
Publikováno v:
Biology, Vol 11, Iss 11, p 1613 (2022)
Fatty acid binding protein-4 (FABP4) is not normally expressed in the liver but is induced in alcohol-dependent liver disease (ALD)). This study sought to identify mechanisms whereby ethanol (EtOH) metabolism alters triglyceride accumulation and FABP
Externí odkaz:
https://doaj.org/article/a7b40bb5175f4ac2b59faa900b5a4f88
Autor:
Iain H. Kalfas
Publikováno v:
Frontiers in Surgery, Vol 8 (2021)
The advancements in computing and digital localizer technologies has led to the evolving clinical application of image-guided technology for the surgical management of spinal disorders. Image-guided spinal navigation addresses the limitations of fluo
Externí odkaz:
https://doaj.org/article/5f743403d3684f8ab458f46562efbd4a
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100975- (2021)
Fatty liver disease (hepatosteatosis) is a common early pathology in alcohol-dependent and obese patients. Fatty acid binding protein-4 (FABP4) is normally expressed in adipocytes and macrophages and functions as a regulator of intracellular lipid mo
Externí odkaz:
https://doaj.org/article/232791548c8e403aa350844032b4ebc9