Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Iain G. Martin"'
Publikováno v:
Cancer Research. 69:2050-2056
The importance of loss of the cell-cell adhesion molecule E-cadherin (encoded by CDH1) to tumor progression is well established. However, CDH1 germ-line mutations predispose to the cancer susceptibility syndrome hereditary diffuse gastric cancer (HDG
Autor:
Iain G. Martin, Siraj G. Rajaratnam
Publikováno v:
Pancreas. 33:27-30
OBJECTIVES: Early identification of patients at high risk of complications from acute pancreatitis is important; as yet, no simple and accurate method has been identified. The aim was to evaluate admission serum glucose as a prognostic marker in gall
Autor:
Pauline Harawira, Maybelle McLeod, Parry Guilford, Vanessa Blair, Susan Parry, Amanda Charlton, A Framp, David E. Shaw, Iain G. Martin
Publikováno v:
Gut. 54:461-468
Background: Hereditary diffuse gastric cancer (HDGC) is defined by germline mutations in the E-cadherin gene, CDH-1. The first family in which CDH-1 mutations were identified was a large Maori kindred, where lifetime penetrance is 70%. Prophylactic g
Autor:
Iain G. Martin, Andrew J. Gill
Publikováno v:
ANZ Journal of Surgery. 72:643-646
Background: Upper gastrointestinal cancer is the third most common cause of cancer mortality in New Zealand. Prognosis of these and other cancers is possibly affected by the accessibility of hospitals. Several studies have revealed a reduction in sur
Autor:
Brian Jolly, Iain G. Martin
Publikováno v:
Medical Education. 36:418-425
Background Assessment plays a key role in the learning process. The validity of any given assessment tool should ideally be established. If an assessment is to act as a guide to future teaching and learning then its predictive validity must be establ
Autor:
Iain G. Martin, Luke H Stockwin, G. Eric Blair, Nikolaos T. Georgopoulos, Lindsay J Stanbridge, Maria E Blair-Zajdel, Samantha V. Jones, Torkjel Matzow
Publikováno v:
Journal of Immunological Methods. 259:205-215
Dendritic cells (DCs) are key antigen-presenting cells (APCs) that act as central modulators of cellular immune responses. Genetic modification of DCs has considerable therapeutic potential in the treatment of a wide spectrum of diseases, including c
Publikováno v:
Medical Education. 34:530-534
Objective To assess the relationship between clinical experience, learning style and performance in an objective structured clinical examination (OSCE) in medical students at the end of their first clinical year. Design Prospective study of undergrad
Autor:
D. Davides, Peter M. Sagar, Glenn Miller, Iain G. Martin, Michael Larvin, S. P. L. Dexter, Henry M Sue Ling, Michael J. McMahon
Publikováno v:
The American Journal of Surgery. 179:316-319
Background: Laparotomy remains the commonest intervention in patients with abdominal complications of laparoscopic surgery. Our own policy is to employ relaparoscopy to avoid diagnostic delay and unnecessary laparotomy. The results of using this poli
Publikováno v:
Immunology and Cell Biology
Immunological effector cells must be sensitive to the antigens or environmental signals that indicate that a pathogen is present. To this end, a group of cells known as the professional antigen‐presenting cells have the ability to educate T, B and
Publikováno v:
Journal of Clinical Pathology. 52:701-704
BACKGROUND: A murine monoclonal antibody against the 17-1A epithelial antigen has been shown to be a useful adjuvant therapy in colorectal cancer. Its clinical use could be extended to patients with upper gastrointestinal adenocarcinoma. AIM: To dete