Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Iain Coldham"'
Autor:
Zain Maqsood Cheema, Muhammad Nisar, Humaira Yasmeen Gondal, Sami A. Alhussain, Magdi E.A. Zaki, Iain Coldham
Publikováno v:
Journal of Saudi Chemical Society, Vol 27, Iss 6, Pp 101746- (2023)
A new series of benzotriazole-derived α-substituted hemiaminal ethers have been synthesized as human cholinesterase (hChE) inhibitors with enhanced activity. The synthesized compounds were extensively characterized by 1H NMR and 13C NMR spectroscopy
Externí odkaz:
https://doaj.org/article/a88f28f663274a1c8ec054854b52fca7
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 1480-1484 (2019)
Quinolinium salts, Q+-CH2-CO2Me Br− and Q+-CH2-CONMe2 Br− (where Q = quinoline), were prepared from quinolines. Deprotonation of these salts with triethylamine promoted the reaction of the resulting quinolinium ylides (formally azomethine ylides)
Externí odkaz:
https://doaj.org/article/e977542e4461418d84caf1335fa6b541
Autor:
Iain Coldham, Adam J. M. Burrell, Hélène D. S. Guerrand, Luke Watson, Nathaniel G. Martin, Niall Oram
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 8, Iss 1, Pp 107-111 (2012)
Heating aldehydes that contain a protected hydroxymethyl group, a tethered alkyl chloride and a tethered alkenyl group at the α-position of the aldehyde with an amine sets up a cascade (tandem) reaction sequence involving condensation to an intermed
Externí odkaz:
https://doaj.org/article/fa6422f44092403f858242aa080b7dd3
Publikováno v:
ARKIVOC, Vol 2011, Iss 5, Pp 57-66 (2010)
Externí odkaz:
https://doaj.org/article/f95432f44f6345d98d7ecadbf4eed7fd
Publikováno v:
Organic Letters. 25:987-991
Autor:
Song‐Hee Yeo, Anthony Choi, Sophie Greaves, Anthony J. H. M. Meijer, Ilaria Proietti Silvestri, Iain Coldham
Publikováno v:
Chemistry – A European Journal.
Publikováno v:
The Journal of Organic Chemistry. 87:8819-8823
The base
Autor:
W. Carruthers, Iain Coldham
The fourth edition of this well-known textbook discusses the key methods used in organic synthesis, showing the value and scope of these methods and how they are used in the synthesis of complex molecules. All the text from the third edition has been
Autor:
Bärbel Edelmann-Stephan, Andreas Hochhaus, Sabine Brandt, Nicolas Schröder, Florian Perner, Gurumoorthy Krishnamoorthy, Iain Coldham, Amit U. Sinha, Claudia Waskow, Lars Bullinger, Stefanie Jilg, Philipp J. Jost, Martin Ungelenk, Francesca Palandri, Matthias Mann, Rebecca Austin, Frank Edlich, Tina M. Schnöder, Susann Rahmig, Carolin Herzog, Robert Zeiser, Steven W. Lane, Arno Meiler, Thomas Ernst, Christian A. Hübner, Juliane Mohr, Ashok Kumar Jayavelu, Peter R. Mertens, Nicolas Huber, Florian H. Heidel, Ann Mullally, Berend Isermann
Publikováno v:
Nature
Janus kinases (JAKs) mediate responses to cytokines, hormones and growth factors in haematopoietic cells1,2. The JAK gene JAK2 is frequently mutated in the ageing haematopoietic system3,4 and in haematopoietic cancers5. JAK2 mutations constitutively
Publikováno v:
Synthesis. 52:1273-1278
Simple ketone starting materials with a halide leaving group and an alkene were prepared in one step and heated with glycine or glycine esters to promote a tandem imine formation, cyclization, and dipolar cycloaddition cascade. The chemistry was also